MESSENGER RNA

STRUCTURE OF MESSENGER RNA

STRUCTURE OF MESSENGER RNA

mRNA

Complementary
bases bind with
each other on both
strands.

DNA

Thymine is Uracil U binds with

not present
Adenine A
in mRNA
TRANSCRIPTION
CODING AND NON CODING STRANDS

Transcription

mRNA is indirect
communication of the
Nucleus with the
outside environment.
 CODING AND NON CODING STRANDS

This set codes

for different
proteins

This set
codes for A Gene is an order of sequence for the nucleotides or the
different order of the sequence of polynucleotides making protein
proteins
 CODING AND NON CODING STRANDS

Non - transcribed

Gene should be read in this direction

3’ 5’

5’ 3’

Gene should be read in this direction

 CODING AND NON CODING STRANDS

Transcribed

Non - Transcribed
or
Coding strand

Transcribed strand
or
Template strand
 CODING AND NON CODING STRANDS

Transcribed
Non – transcribed strand
Non – Transcribed
Strand
Or A C C G T A G
Coding strand
Transcribed strand
T G G C A T C or
Template strand
DNA HELICASE IN
TRANSCRIPTION
 DNA HELICASE IN TRANSCRIPTION

Hydrogen bonds between

the bases are broken

Intact double helix

 DNA HELICASE IN TRANSCRIPTION

Helicase recognises the start codon and

proceeds with the unzip of the double helix. A T G

Helicase

UNZIP

This exposes both the non transcribed or coding strand and the transcribed or template
strand.
RNA POLYMERASE IN
TRANSCRIPTION
 RNA POLYMERASE IN TRANSCRIPTION

transcribed

Non transcribed or Coding strand

Free RNA
nucleotides

Template Or Transcribed strand

 RNA POLYMERASE IN TRANSCRIPTION

The RNA nucleotides then joined to adjacent nucleotides

by phosphodiester bonds to form mRNA strand.

Gene is read from 5’ to 3’

mRNA is read from 3’ to 5’ in RNA Polymerase
opposite direction.
RNA POLYMERASE IN TRANSCRIPTION

Double helix
DNA

mRNA
SPLICING
SPLICING

Transcription

DNA mRNA

DNA

Primary transcription

Pre-mRNA

Modified

mRNA
 SPLICING

I E I E I
 SPLICING

E I E I E

EXONS = USEFUL
SPLICING

Mature mRNA