Name: DUNGOG, DANIEL MARK A.

Year level & Section: BSN 3 - NO2

NAME OF DRUG DOSAGE/FRE CLASSIFICATION MECHANISM OF INDICATIONS/ CONTRAINDICATION SIDE EFFECTS NURSING
Q/ ACTION RESPONSIBILITIES
ROUTE/SUPP
LIED
GENERIC NAME Hypertension Labetalol is in a Labetalol Labetalol injections Asthma, overt heart - Fatigue BEFORE:
Labetalol 100 mg PO class of non-selectively are indicated to failure, greater than - Nausea - Assess the
q12hr initially; medications called antagonizes control blood first-degree heart block, - Dizziness patient's baseline
BRAND NAME increased by beta blockers. It beta-adrenergic pressure in severe vital signs,
cardiogenic shock, - Diarrhea
Trandate 100 mg q12hr works by relaxing receptors, and hypertension. medication history,
blood vessels and selectively Labetalol tablets are severe bradycardia, or - Shortness and any drug
every 2-3 days
Usual dosage slowing heart rate antagonizes indicated alone or in other conditions that of breath allergies.
range: 200-400 to improve blood alpha-1-adrenergi combination with can cause severe, - Assess the patient
mg PO q12hr; flow and decrease c receptors. antihypertensives like prolonged hypotension, for specific
not to exceed blood pressure. Following oral thiazides and loop and hypersensitivity to contraindications
2400 mg/day administration, diuretics to manage labetalol are to receiving
labetalol has 3 hypertension. labetalol and
contraindications to its
times the advise the
beta-blocking administration. practitioner
ability than accordingly.
alpha-blocking
ability. This DURING:
increases to 6.9 - Monitor BP and
times following pulse during
intravenous dosage adjustment
administration. period. Use
Antagonism of standing BP as
alpha-1-adrenergi indicator for
c receptors leads making dosage
to vasodilation adjustments for
and decreased oral drugs and
vascular assessing patient's
resistance. This tolerance of
leads to a dosage increases.
decrease in blood
pressure that is AFTER:
most pronounced
while standing. - Note: Postural
Antagonism of hypotension is
beta-1-adrenergic most likely to occur
receptors leads to during peak
a slight decrease plasma levels (i.e.,
in heart rate. 2–4 h after drug
Antagonism of administration).
beta-2-adrenergic - Do not let the
receptors leads to patient drive or
some of the side engage in other
effects of labetalol potentially
such as hazardous
bronchospasms, activities until
however this may response to the
be slightly drug is known.
attenuated by
alpha-1-adrenergi
c antagonism.
Labetalol leads to
sustained
vasodilation over
the long term
without a
significant
decrease in
cardiac output or
stroke volume,
and a minimal
decrease in heart
rate.

Reference:
https://go.drugban
k.com/drugs/DB00
598