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1 College of Medicine, Drexel University, Philadelphia, Pennsylvania Address for correspondence Sammy Othman, BA, Drexel University,
2 Department of Otolaryngology - Head and Neck Surgery, Philadelphia 2900 West Queen Lane Philadelphia, PA 19129
College of Osteopathic Medicine, Philadelphia, Pennsylvania (e-mail: sothman13@gmail.com).
3 Drexel University College of Medicine, Philadelphia, Pennsylvania
4 Facial Plastic Surgery, Main Line Center for Laser Surgery, Ardmore,
Pennsylvania
Facial Plast Surg
Human aging is marked by a progressive loss of volume one of which being aesthetic enhancement of the temporal
and tissue elasticity in the face.1,2 Fat and muscle compo- anatomy for concavity correction.6 Several approaches
nents are particularly important in the shaping of the exist, including the use of grafts, implants, fillers, and
upper face region, and as the aging process occurs, a loss flaps. The method employed is dependent upon the goal
of soft tissue in the temporal area can result in a hollowed, of the procedure as well as clinician preference.7–9 Despite
gaunt appearance.3,4 This can be perceived as unappealing the variety of methods available for aesthetic temporal
due to increased facial concavity and can lead patients to augmentation, there is no comprehensive literature
seek correction of this area and achieve a more youthful or review of these various techniques. The purpose of this
aesthetically pleasing appearance.3,5 Temporal augmenta- systematic review is to describe the existing surgical
tion is a versatile procedure used for a variety of purposes, methodology and technique-specific complications and
Issue Theme Applied Anatomy for Facial Copyright © by Thieme Medical DOI https://doi.org/
Plastic Surgery; Guest Editors: Yves Publishers, Inc., 333 Seventh Avenue, 10.1055/s-0039-1694029.
Saban, MD, PHM, Peter Palhazi. New York, NY 10001, USA. ISSN 0736-6825.
Tel: +1(212) 584-4662.
Temporal Augmentation Othman et al.
Fig. 1 Search strategy and results. Detailed processes of the search strategy, stratification, and results.
Abbreviations: FDA, U.S. Food and Drug Administration; SVF, stromal vascular fraction.
patients to be overall satisfied with the results (►Table 2) to the superficial temporal fascia followed by a more superfi-
without major complications (►Table 3).16 cial, subcutaneous layer injection in the surrounding areas.19
Patients reported high satisfaction rates (►Table 2). Postoper-
Targeted Fat Volume Restoration atively, 94.8% of patients reported no or mild hollowness on
Recently, there has been a surge in interest for targeted volume the Hollowness Severity Rating Scale (HSRS).19,20 Minor com-
restoration. Recent studies have demonstrated an increased plications were reported (►Table 3). Volume restoration was
natural appearance along with decreased complications.17,18 also measured with a three-dimensional (3D) topographic
Huang et al used harvested fat to inject fat compartments deep scan, which showed a 91.8% increase in augmentation.
Revision
One variation of pure fat grafting is SVF-assisted cell therapy.
12.2%
6.3%
NOS
14%
Previous literature showed that adipose stem cells increased
1
graft survival time through the promotion of vasculogenesis.21
-
Li et al demonstrated this method by fat harvesting with
Facial nerve
6.3%
2.4%
tional fat harvesting injected into various facial sites including
0
-
-
-
the temporal region. Volumes were measured using computed
tomography (CT) scans. The mean graft survival was 64.8 for
pain
Jaw
5%
5%
the SVF group and 46.4% for the control group at 6 months
-
-
-
-
-
-
postinjection. There were no reported complications
Tenderness/
2.4%
70%
Fillers
-
-
-
-
The advent of fillers allows for contouring and volumization of
asymmetrical or aged areas for a more aesthetic perception.23
0%
0%
0
-
-
-
-
-
5.2%
rash
10%
55%
Hyaluronic Acid
0%
0%
-
-
-
-
-
-
2.4%
3.1%
40%
30%
50%
0%
30%
65%
-
-
-
-
None
Pain
55%
80%
-
-
-
-
Hirohi et al (2018)
Moradi et al 2011
Byrd et al (1993)
Lee et al (2017)
Li et al (2013)
HA.29 Juvéderm was not used, as it was it cited to have a tion and extrusion.35,36 Traditional complications are also
higher degree of injection difficulty due to its viscosity. The possible, including seroma, hematoma, and infection.36 In
hypothesis behind this method is a greater volume of solu- our review, we identified studies using methyl methacrylate
tion allowing for greater distribution of filler for a more (MMA) and polytetrafluoroethylene (PTFE) implants for
uniform, smooth look, extending from the lateral orbit/ aesthetic temporal augmentation.
eyebrow throughout the temporal area. The author reports
a high degree of satisfaction (►Table 2) with small, correct- Methyl Methacrylate
able adverse effects (►Table 3). Methyl methacrylate is a resin used for craniofacial and
temporal augmentation.37,38 This material successfully
Calcium Hydroxyapatite addresses full-thickness defects of the skull while being mal-
Calcium hydroxyapatite is a mineral found endogenously leable, biocompatible, and nonabsorbable. In addition, it is low
within human teeth and bone. It is a well-studied material, in cost and produces a predictable result.39,40 Unlike other
and its efficacy as a filler stems from its versatility and ability to implants, MMA is placed in a submuscular pocket rather than a
act as scaffolding material and stimulate growth of surround- supramuscular pocket, which significantly reduces damage to
ing tissue, more specifically collagenous dermal material.30 the frontal branch of facial nerve.39 Gordon and Yaremchuk
Moreira-Gonzalez et al studied porous hydroxyapatite gran- briefly discussed their experiences and results with MMA for
ules as filler material. Of note, the study combined aesthetic, aesthetic temporal augmentation.39 Satisfaction and appear-
complications can allow providers to opt for the best individ- biocompatibility, minimal foreign body reaction, low extru-
ualized option for their patients. sion rate, and lack of excessive capsule formation.37,55 Porous
One goal of a cosmetic procedure is to achieve a high level of polyethylene implants are mainly used for bone due to its
patient satisfaction. Understanding which techniques are most stiffness.37 In addition, these implants have micropores, which
effective in terms of patient satisfaction is difficult to accom- allow surrounding tissue to grow through lattice networks as
plish within a systematic review. The articles we examined opposed to encapsulation. The vascularized soft tissue
were largely retrospective reviews, whereas the prospective network throughout the implant reduces the likelihood of
studies were not randomized trials. Qualifying patient satis- infection and movement over time.37,39,55 In contrast, materi-
faction can be accomplished by standardizing age, gender, als with larger pore sizes can experience material breakdown
and degree of temporal volume deficits. Some studies used a and foreign body reactions when used improperly, such as
previously validated and standardized scale (HSRS), with woven Teflon and organic fibers (i.e., Proplast; Vitek Inc.).56,57
blinded reviewers and follow-up times in an attempt to The Eppley temporal shell implant, produced by Implantech, is
standardize results. Unfortunately, most of the other studies another option used by the senior author (J. B.) with good
relied on self-reported patient satisfaction scores. The majority results. Composed of solid silicone, it is believed to be advan-
of patients were satisfied with their procedures, with varying tageous due to its soft composition when compared against
categorization (►Table 2). The different measurement scales other silicone implants. This allows for greater contour adap-
were not standardized, which can skew results. Future tation to the natural shape of the skull.58 No studies have
calcification and tissue necrosis.64 The long-standing issue augmentation has not been well described previously. We
with fat grafting, however, is the lower rate of survival owing were able to examine the existing methods used for aesthetic
to the lack of vascularization.65 temporal augmentation, which should encourage further
Bone grafting is another alternative used for temporal research on this topic.
augmentation. Temporal hollowing, for example, is a rela-
tively known common complication of craniotomies. Several Conflicts of Interest
studies cite autologous bone graft, often calvarial, as an Dr. Bloom reports personal fees from Allergan, Galderma,
effective method following craniotomy to combat loss of Merz, ThermiAesthetics, InMode, Prollenium, Revance
volume in the temporal area.66 Given the invasive nature of Therapeutics, Endo Pharmaceuticals, and Evolus outside
these procedures, they are unlikely to be used in aesthetic the submitted work. The other authors have no conflict of
temporal augmentation when compared with time-saving interest to disclose.
and cost-intensive options mentioned in this review.
We initially intended to include flap-based strategies for
cosmetic temporal augmentation. Flaps are vascularized References
1 Paskhover B, Durand D, Kamen E, Gordon NA. Patterns of change
tissue consisting of skin, fat, muscle, bone, or a combination
in facial skeletal aging. JAMA Facial Plast Surg 2017;19(05):
of these materials. No flap research met the inclusion criteria 413–417
in this review, as this has traditionally been a reconstructive 2 Wilson MV, Fabi SG, Greene R. Correction of age-related midface
17 Wang W, Xie Y, Huang RL, et al. Facial contouring by targeted 40 Hirohi T, Nagai K, Ng D, Harii K. integrated forehead and temporal
restoration of facial fat compartment volume: the midface. Plast augmentation using 3D printing-assisted methyl methacrylate
Reconstr Surg 2017;139(03):563–572 implants. Aesthet Surg J 2018;38(11):1157–1168
18 Zhou J, Xie Y, Wang WJ, et al. Hand rejuvenation by targeted 41 Fedok FG, van Kooten DW, Levin RJ. Temporal augmentation with
volume restoration of the dorsal fat compartments. Aesthet Surg J a layered expanded polytetrafluoroethylene implant. Otolaryngol
2017;38(01):92–100 Head Neck Surg 1999;120(06):929–933
19 Huang RL, Xie Y, Wang W, Tan P, Li Q. Long-term outcomes of 42 Saygun O, Topaloglu S, Avsar FM, et al. Reinforcement of the suture
temporal hollowing augmentation by targeted volume restora- line with an ePTFE graft attached with histoacryl glue in duodenal
tion of fat compartments in Chinese adults. JAMA Facial Plast Surg trauma. Can J Surg 2006;49(02):107–112
2018;20(05):387–393 43 McKeown ADj, Beattie RF, Murrell GA, Lam PH. Biomechanical
20 Moradi A, Shirazi A, Moradi J. A 12-month, prospective, evaluator- comparison of expanded polytetrafluoroethylene (ePTFE) and
blinded study of small gel particle hyaluronic acid filler in the PTFE interpositional patches and direct tendon-to-bone repair
correction of temporal fossa volume loss. J Drugs Dermatol 2013; for massive rotator cuff tears in an ovine model. Shoulder Elbow
12(04):470–475 2016;8(01):22–31
21 Rehman J, Traktuev D, Li J, et al. Secretion of angiogenic and 44 Batniji RK, Hutchison JL, Dahiya R, Lam SL, Williams EF III. Tissue
antiapoptotic factors by human adipose stromal cells. Circulation response to expanded polytetrafluoroethylene and silicone implants
2004;109(10):1292–1298 in a rabbit model. Arch Facial Plast Surg 2002;4(02):111–113
22 Li J, Gao J, Cha P, et al. Supplementing fat grafts with adipose 45 Lin J, Chen X, Zhang W, Xu L, Zheng X. Temporal augmentation
stromal cells for cosmetic facial contouring. Dermatol Surg 2013; using a polytetrafluoroethylene implant with the assistance of an
39(3 Pt 1):449–456 endoscope. Aesthetic Plast Surg 2010;34(06):701–704
generation polycaprolactone-based collagen stimulator (Ellansé®). 67 Güven E, Kuvat SV, Aydin HU, Yazar M, Emekli U. Facial
Clin Cosmet Investig Dermatol 2017;10:431–440 contour reconstruction with temporoparietal prelaminated
63 Moers-Carpi MM, Sherwood S. Polycaprolactone for the correc- dermal-adipose flaps. J Craniomaxillofac Surg 2010;38(05):
tion of nasolabial folds: a 24-month, prospective, randomized, 374–378
controlled clinical trial. Dermatol Surg 2013;39(3 Pt 1):457–463 68 Wolff KD, Kesting M, Löffelbein D, Hölzle F. Perforator-based
64 Yoshimura K, Coleman SR. Complications of fat grafting: how they anterolateral thigh adipofascial or dermal fat flaps for facial
occur and how to find, avoid, and treat them. Clin Plast Surg 2015; contour augmentation. J Reconstr Microsurg 2007;23(08):
42(03):383–388, ix 497–503
65 Pu LL. Mechanisms of fat graft survival. Ann Plast Surg 2016;77 69 Bullocks J, Naik B, Lee E, Hollier L Jr. Flow-through flaps: a review
(Suppl 1):S84–S86 of current knowledge and a novel classification system. Micro-
66 Kim JH, Lee R, Shin CH, Kim HK, Han YS. Temporal augmentation with surgery 2006;26(06):439–449
calvarial onlay graft during pterional craniotomy for prevention of 70 Woodard CR. Complications in facial flap surgery. Facial Plast Surg
temporal hollowing. Arch Craniofac Surg 2018;19(02):94–101 Clin North Am 2013;21(04):599–604