I. Blood a, Red Blood Corpuscles . Rouleaux formation is defined as an aggregation of which of the following? RBCS . Platelets Lymphocytes . Neutrophils Megakaryocytes . Rouleaux formation occurs as a result of which of the followings? Genetic defect in haemoglobin. Slow circulation. Increase neutrophils/ lymphocytes. |. Hypoproteinemia. . Reduction in the number of platelets. . When the majority of RBCs measures less than 6um in diameter the condition is termed: Anisocytosis. . Macrocytosis Microcytosis |. Poikilocytosis, . Spherocytosis. . Macrocytes define the RBC when its diameter is: . “4yim 2 6pm 7um 8um 10pm. . What is the terminology diameter of RBCs? a. Anisocytosis, . Macrocytosis - Microcytosis that describes the great variation in the * Poikilocytosis, ~ Spherocytosis6. What is the terminology that describes the abnormal shape of RBCs? a. Anisocytosis. b. Macrocytosis c. Microcytosis d. Spherocytosis e. Hypochromasia Which of the following stains is suitable for staining of blood a. Toluidine blue. b. PAS. c. Leishman. d. Van Gieson. e. Mallory. . All of the followings characterizes the structure of the RBCs EXCEPT: a, They are surrounded by'lipoprotein cell membrane. b. Their inner surfacevof eell membrane is associated with cytoskeleton proteins. c. Their outer surface contains genetically determined antigens. d. They lack nucleus: e. They contaimorganelles. . The genetically determined antigen related to the blood groups in the RBCs is associated with which of the following structures? a. (Cytoplasm. b.. Nucleus. cm Glycocalyx. ‘d> Transmembrane protein. ‘e. Cytoskeleton proteins. . Biconcave shape of the RBCs is maintained due to the presence of which of the followings? a. Absence of nucleus. Absence of the organelles. Presence of glycolytic enzymes. Molecular structure of the cell membrane. Presence of hexose monophosphatse shunt. pases 5 scanned with Gamscanner11. Which of the following proteins is responsible for maintaining the characteristic shape of RBCs? a. Spectrin b. Myosin. c. Desmin d. Keratin. Vi in. = 12.4 ae oat female patient suffered ion easy fatigability, ‘ion reveals. pale appearance and slow growth. lab examinat - tic anemia. She was diagnosed as. haying hypochromic microcy' it eee Which of the following structures of.the RBEs is defective? ‘a. Lipoprotein membrane. b. Cytoskeleton proteins. c, Hemoglobin. d. Glycocalyx e. Spectrin and ankyrin. 13. 10-year-old boy suffered from easy fatigability, pale appearance, yellowish discoloration ofthe skin and enlarged spleen. He was diagnosed as having hereditary spherocytosis. Which of the following structures Of the RBCs is the underlying cause? ‘a. Cholesterol component of cell membrane. b. Lipid bilayer of cell membrane. c. Hemoglobin. d. (Glydocalyx ©. Spettrin and ankyrin. 14. High'selectivity of the cell membrane of RBCs allow them to perform which of the following functions? a. Prevents escape of Hb outside the cell. b. Changes the shape of the cell. c. Resists their damage. d. Provides flexibility to squeeze. e. Gives more space for Hb, 15. aa pea : hee i of the cell membrane of RBCs of the following functions? a. Prevents escape of Hb outside the cell. scanned with Camscannerb. Gaseous exchange. c, Increase surface area. d, Provides flexibility to squeeze. e. Gives more space for Hb, 16, Absence of the nucleus and organelles of RBCs allow them to perform which of the following functions? a. Prevents escape of Hb outside the cell, b. Changes the shape of the cell. c. Resists their damage. d. Provides flexibility to squeeze. e. Gives more space for Hb, 17. Biconcave shape of RBCs ada functions? a. pts which of the following Prevents escape of Hb outside thé cell. . Changes the shape of the cell, Resists their damage. |. Provides flexibility to ‘Squeeze. Increases surface area for gas exchange. epee b: leukocytes 18. Leukocytes differ from erythrocytes in all of the following EXCEPT: a. Theyarevtrue cells having nuclei and organelles. b. TheyrarSiatger, c, Theyrare more numerous, d) They have shorter life span. ©.) They have a role in immunity, 19. Which leukocytic cells have multilobed deeply stained nucleus? a. Neutrophils. b. Eosinophils, ¢. Basophils. d. Monocytes. ©. Lymphocytes. 20. In blood film under normal condition band neutrophils Constitute: a. 20% 7 scanned with Camscannerwab) Cc d. 5% — e. 2% 21. The nuclei of b: a. Multilobed. b. Bilobed. c, Rounded ind d. Horse-shoe e. Flattened. vt 22. All of the followings are tru a. They are present in some b. They are seen in human female. c. They appear as drum stick d. They are inactive X chro mK e. They appear as fine cytop! ic\granules. 23. Leukocytes differ from e1 ich of the following? ° Bad z SS sosomes. ~~ Proteasomes. 25»Neutrophilic granules differ than azurophilic granules in: a. Constitute 80% of the granules. b. They represent lysosomes. c. They contain proteolytic enzymes. d. They are considered tertiary granules. ics They are present in all granular Jeukocytes. 26. Which is TRUE about tertiary granules? a. Constitute 80% of the granules.tes? a. Eosinophils. b. Neutrophils. c. Basophils. d. Lymphocytes. e. Monocytes. 31. Alll of the following are characteristic for the internum of the membrane bounded granules of eosinophils EXCEPT: a. They electron dense. 9 scanned with Camscannerb. They are external in position. | cc, They contain major basic protein. d. They contain cationic protein. e. They contain neurotoxin. . 32. The Beats of the membrane bonded granules differs than the internum in which of the following? a. They are less electron dense. b. They are present in the core. c. They contain major basic protein. d. They contain cationic protein. » e. They contain neurotoxin. 33. During hypersensitive reaction which of the followingicells produces histaminases. a. Mast. b. Plasma. c. Eosinophils. 4. Basophils. e. Macrophages. 34. Which of the following cells are character! parasitic infections? a, Eosinophils. b. Neutrophils. c. Basophils) d. Bymphocytes) e. (Monocytes. 35. Whieh bf the following characterize the nuclei of eosinophils? am Multi-lobed deeply stained. b Bi-lobed faintly stained. c. S shaped faintly stained d. Rounded indented deeply stained. e. Rounded indented lightly stained. istically increased in 36. Which of the followin g leukocytes are metachromati i with toluidine blue stain? a a. Eosinophils. b. Neutrophils. c. Basophils. 10 scanned with Camscanner‘dl Lymphocytes. e. Monocytes. 37. Which of the following characterizes the basophilic specific granules? a. They are not surrounded by a membrane. b. They mask the nuclei. c. They are electron lucent. d. They have electron dense core. e. They contain hydrolytic enzymes. 38. Basophils are similar to which of the following connective tissue cells? a. Mast. b. Plasma. c. pericytes. d. Fibroblasts. e. Macrophages. 39, Basophils are resembling mastcells in which of the following? a. They contain heparin and histamine. b. They contain few azurophilic granules. c. They have week phagocytic activity. d. They are components of loose connective tissues. e. They containhydrolytic enzymes. 40. Which of the following leukocytes have receptors for Ig E? a. “Mymphoeytes. b. (Buympiocytes x Neutrophils. ds. Basophils. €* Monocytes. 41>Medium lymphocytes differ than small lymphocytes in which of the following? a 7 b, a d. They constitute 92% of circulating lymphocytes. Their size range from 6-8 hm. They have rounded indented nuclei. ‘They have abundant rER and well developed Golgi complex. o Ne They contain few mitochondria. ‘ural Killer cells are considered: > at scanned with GamscannerSmall lymphocytes. Medium lymphocytes. Large lymphocytes. T lymphocytes. e. B lymphocytes. 43. Which of ae is a characteristic for small lymphocytes? a. Presence of specific surface markers. b. Few free ribosomes. c. Many azurophilic granules. d. Absence of surface microvilli. e. Abundant rER and well developed Golgi complex. 44. T lymphocytes differ from B lymphocytes in which of the followings? a. They constitute 15% of small lymphocytes: b. They develop in bone marrow. c. They live for about 3 months. d. They have surface markers for immunoglobulin receptors. e. They are located in’thymus dependent zones. 45. All of the followings are characteristic for antigen presenting cells EXCEPT? a. They are derived from the thymus. b. They haye.the capacity to partially digest antigens. c. They break the.Ag into small peptides. d. ‘They are nécessary for antigen processing. ec. (They.are necessary for activation of T lymphocytes. 46. Which of the followings is a function of T cytotoxic cells? a», Suppressing the activity of immuno-competent cells. b> Releasing cytokines. c. Facilitating secondary response to the same antigen. d. Destroying foreign cells by direct contact. e. Activating T and B lymphocytes. 47. Which of the followings is a function of T helper cells? a. Suppressing the activity of immuno-competent cells. . Releasing cytokines. palo ecaic b, c. Facilitating secondary response to the same antigen. d. Destroying foreign cells by direct contact. 12 scanned with Gamscannere. Digesting the antigen partially. 4g, Which of the followings is a function of T memory cells? a, Suppressing the activity of immuno-competent cells. b. Releasing cytokines. c. Facilitating secondary response to the same antigen. d. Destroying foreign cells by direct contact. e. Activating T and B lymphocytes. 49. All of the followings are characters of monocytes EXCEPT: a. They are the largest leukocytes. b. Their nuclei are large and kidney shaped. c. Their cytoplasm show frosted glass appearance. d. Their cell membranes show pseudopodia, . They contain few lysosomes. 50. Which of following cells migrate from the peripheral blood, change and activated in the connective tissue? a. Pericytes. b. Macrophages. c. Mast cells. d. Monocytes. e. Basophils. 51. Abnormal increase inthe leukocyte precursors in the bone marrow is described as: a. Thalassemia. . Sickle celManemia. Hemolytic anemia. Deukemia. Thrombocytopenic purpura. S30 5 c. Thrombocytes (blood platelets) 52. Severe reduction in the number of platelets in circulating blood causing bleeding is described as: a. Thalassemia. Sickle cell anemia. Hemolytic anemia. Leukemia. enos Thrombocytopenic purpura. 13 scanned with Camscanner53. Which of the followings is a content of Hyalomere of blood platelets? a. Actin and myosin filaments. b. Alpha granules. ¢. Dense bodies. d. Lambda granules. e. Mitochondria. 54. Which of the followings is a content of Granulomere of blood platelets? a. Actin and myosin filaments. b. Dense bodies. ¢. Microtubules. d. Surface opening tubular system. e. Dense tubular system. 55. Which of the following structures are involved in platelet adhesion? a. Actin and myosin filaments. b. Dense bodies. c. Microtubules. d. Two tubular'systems, e. Glycocalyx, 56. Blood platelets, resemble erythrocytes in which of the followings? a. They contain mitochondria b. Their outer surface is covered by glycocalyx. c. (They have granular cytoplasm. @.. They have two tubular systems. ex They contain lysosomes. d. Hemopoiesis 57. Red bone marrow differs from yellow marrow in which of the followings? a. High content of fat cells. b. An inactive type. ¢. Present in diaphysis of long bone. d. Can change to yellow bone marrow, e, They are responsible for production of blood cells. 14 scanned with Camscannerveloped Golgi apparatus. . They have well de divided into small areas su d. Their cytoplasm is cell membrane. e. They extend their processes in-between en 64. Which of the followings describe the co in hypertonic solution? a. Crenation. p. Shperocytosis. ¢. Poikilocytosis d. Macrocytosis. e. Microcytosis. 65. Which of the followings describe the condition 6f placing RBCs in hyotonic solution? a. Crenation. b. Shperocytosis. ¢. Poikilocytosis. d. Macrocytosis. e. Microcytosis 66. Presence of enzymes for glycolysis within the RBCs replaces which of the following structures? a, Nucleus. b. Mitochondria, c. Spectrin, 4. Ankyrin e. (Hemoglobin. rounded by a dothelial cells. ndition of placing RBCs