CHEMICAL ENGINEERING DEPARTMENT

V.V.P ENGINEERING COLLEGE, RAJKOT.

:
SUB A SUMMER INTERNSHIP REPORT ON ADEN PHARMACEUTICALS .

SUBMITTED BY: PATEL DEEP JAYESH

GUIDED BY: AJINKYA PATWARDHAN

 CERTIFICATE

This is to certify that Mr. Patel Deep Jayesh (180470105039) student of B.E. (Chemical Engineering),
6th semester, studying in V.V.P Engineering College, Rajkot, has satisfactorily completed the summer
internship at ADEN PHARMACEUTICALS PVT LTD as a partial fulfilment towards the degree of B.E. in
Chemical Engineering.

Date: 16/05/2021

Ajinkya Patwardhan Dr. Piyush Vanjara

(PROFESSOR ) (HEAD OF DEPARTMENT)
 ACKNOWLEDGEMENT

It gives me immense pleasure to express my deep sense of gratitude to my guide Ajinkya

Patwardhan Assistant Professor Chemical Engineering Department, V.V.P. Engineering
College, Rajkot for his invaluable guidance, motivation, constant inspiration and above all for
his ever co-operating attitude that enabled me in bringing up this report in the present form.

I am also extremely thankful to Dr. Piyush Vanzara, Head of Department, Chemical

Engineering Department, V.V.P. Engineering College, Rajkot and all faculty members of
Chemical Engineering Department, V.V.P. Engineering College, Rajkot .

I am greatly thankful to all my well-wishers, classmates and friends for their inspiration and
help.
 ABSTRACT

This report describes the internship I completed in Aden pharmaceutical in Vadodara. The report gives
the information about different products that the company manufacture and also gives advantages and
uses of intermediate products produced. My major goal was to learn the industrial view in pharmaceutical
field from my internship. During my internship I learned to operate different agitated vessels and different
cooling towers. And also I actively participated in all the work given by manager and directors and overall
I am very satisfied with the results of my internship. I hope to use my knowledge and apply it in a real
organization.
 CONTENT

1)Introduction
2)Structure
3)Raw Materials
4)Products
5)Safety measures
6)Overview
 Introduction

From the year 2006, when the commencement of Aden Pharmaceuticals Private
Limited was placed, the firm is running its manufacturing Mercaptan Benzimidazole,
API Intermediate and Omeprazole Intermediates. Our esteemed consumers recognize
the quality in our chemicals, simultaneously with its pure composition, and possibly
our ethical business skills. We take contentment in promoting the extension and
prosperity of our brand, which furnishes us to make our company’s perception a
substance of pioneering the chemical industry.

We intend to swell our footstep by proceeding to formulate products with a progressive

strategy and effective growth policy. We own roomy and extremely prolific
manufacturing systems implemented with advanced machinery to decrease the
operational costs. Due to our quality support laboratories, we can concentrate on the
local business needs of quality and come up with a precisely formulated product that
elevates the bar of our expertise. Our responsibility to serve our respected clients across
the nation supported us to increase the mark the recognition and to sustain a vigorous
future.

Mr. Dilip Dholakia, our mentor is one of the several minds that we have accomplished
technical perfection. He is an ambitious manufacturer with the rich expertise of
chemical engineering and sound experience of the marketplace. His dedication in
bringing benefit to the company is displayed in the productivity and effectiveness of
every team member.
 STRUCTURE
There were 5 Sections in the Company.
1)Raw material storage section
All the Raw materials are stored in this section.

2)Production Section
There were 5 Stainless steel Reactor.
There was a Receiver, receiving material from Condenser.
There were many Centrifuges for removal of water from intermediate.

There were also Filter Press.

There was a Newly Purchase Agitated Filter Dryer.

To cool the product there were Cooling towers.

There was also a Steam boiler for heat Generation.

There were many Compressors attached to the reactors.

There was a air compressor available.

3)Analytical Lab
All the required properties for the product are checked in the analy tical lab.
In Analytical Lab, we were taught how to use the Gas chromatographer, High
pressure liquid chromatographer using the desired graphs in the LC solution
Software.
To check Gaseous moisture, we used Moisture Content.
To check liquid moisture, we used Karl Fischer apparatus .
4)R and D section
Various Improvement ideas were implemented in R and D section.
We were not taught anything due to Privacy policy.
5)Treatment Section
There was a ME section and a ETP section.

In ME section, Wet scrubbing was the process for removal of certain target particles
from used solution.
Harmful particles (pollutants) are removed.
In the ETP , the PH of the used Solvent or the liquid discarded are measured and made
perfect up to certain PH required according to Government Norms, so it can be
discarded.
In ETP the required colour for discharge is also met.
 Raw Materials

As soon as we enter in the company, we see the raw materials storage

section. The raw materials available are:
1) R 22 Gas

R 22 Gas is stored in tanks.

2)Caustic Soda:
The raw material is Caustic flakes, and the Caustic Lye storage tanks were also seen at the
site.
 3)SCN -IPA
It is stored in blue container.

4)Acids
The acid used are HNO3 and HCL.They are stored in Stainless steel storage tank because of
their Acidity.

.
 PRODUCT DETAILS.
1) Mercapto Benzimidazole
Offering you a complete choice of products which include 2 Mercapto Benzimidazole,
Methoxy 2 Mercapto Benzimidazole, 5-(Difluoromethoxy)-2-Mercapto-1H-
Benzimidazole and 2 Mercapto Benzimidazole Powder.
a) Mercapto Benzimidazole

Grade Standard Technical Grade

Physical State Powder
Packaging Size 25 KG
Packaging Type Bag
Molecular Weight 150.199 g/mol
Molecular Formula C7H6N2S
Melting Point 253 Degree Celsius
Density 1.42 g/cm3
Brand Aden
b) Methoxy 2 Mercapto Benzimidazole

Brand Aden
Packaging Size 25 kg
Packaging Type Bag
Molecular Formula C8H8N2OS
Molecular Weight 180.23 g/mol
Cas No 37052781
Intermediate for Manufacture of the Anti-ulcer
Applications
Drug Omeprazole.
Einecs No 2533262
c) Methoxy 2 Mercapto Benzimidazole

Brand Aden
Packaging Size 25 kg
Packaging Type Bag
Molecular Formula C8H8N2OS
Molecular Weight 180.23 g/mol
Cas No 37052781
Intermediate for Manufacture of the Anti-ulcer
Applications
Drug Omeprazole.
2533262
Einecs No
d) 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole

Brand Aden
Packaging Size 25 kg
Packaging Type Bag
Moleclular Weight 216.21 g/mol
Linear Formula C8H6F2N2OS
UNSPSC Code 12352100
PubChem Substance ID 24878590
MDL Number MFCD00467504
2) 5 Difluoromethoxy 2 Mercapto Benzimidazole

Packaging Size 25 kg
Packaging Type Bag
Boiling Point 127 Degree Celsius
Molecular Formula C18H21N3O3S
Brand Aden
Molar Mass 359.444 g/mol
Safety Measures
 Conclusion

Overall it was a nice experience to understand the industrial view and use of many equipment
we study as a theory portion.
The staff was very nice at the site.
We were provided by guide by our mentor Ashokbhai.
Our guide were Vivekbhai, Pratikbhai and Rahulbhai.
I would also like to thank my College Mentor Ajinkya Sir for providing support for my 2 weeks
Internship.