HUBAIBL SDERWATOLOGIST TRSTE BLP.285 ABD--- DECEMB JANUARY 20 ‘\. Which of the following cytokines characteristically promotes the proliferation of lvmphokine-activated kill s? fA. Interferon-gamma IB. Interleulsin 1 £@) interle 10 FE. ‘Tumor necrosis factor-alpha kin 2 1D, Interleukin ~old man is taking oral methotrexate for psoriasis and has severe 2 aarye the most appropriate nausea with each dose. Which of the followin treatment for this symptom? Vitamin D3 £. Riboflavi 3 Mutations of the human homologue of the fruit fly patched gene are associated with FO basal cell nevus syndrome. CB. Darier's disease. MC. familial psoriasis, !D, Grover's disease. !”. pachyonychia congenita 4 Glomus cells contain abundant A. keratin filaments. TB. lysosomal enzymes. FC. myelinated fibers. 1D) myofilaments, IE, Weibel-Pelade bodies } Which pattern of ANA immunofluorescence are patients with mat-like telangiectasia, esophageal dysmotility, scterodactyly, and Raynaud's phenomenon likely to exhibit? A, Homogeneous 1B. Nucleolar C. Particulate ™D. Peripheral MQ) Spechled WY Which test can most effectively confirm the diagnosis in ad Chediak-Higashi syndron Blood smear 1B, Intradermal skin test to recall antigens UC. Nitroblue tetrazolium test © D. Serum immunoglobulin levels #E. Skin biopsy# Spirochetes are best demonstrated with which stain? BD. Warthin-Starry CB. Ziebl-Neelson °C Brown-Brenn E. Alizarin red to induce elastosis perfor ns 8 Which of the following drugs has been repo! serpiginosa? fA. Busulfan CB. Cyclosporine C. Gold Sb. Methotrexate MB) D- penicillamine 7 Triangular lunulae are pathognomomte tor nz isease associaied with TA. DOPA TB. Fontana-Masson TC, Acid orcein FD. Verhoeff-von Gieson *€B) von Kossa led with KX) H epidermolysis bullosa simptex of the t mutation of the genes coding for TA. filagerin. OB. fibrillin. C. keratins 1 and 10. ™D. keratin 9. RQ) keratins 5 and 14, 72 Which ot the following drugs has been associated with linea dermatosis? 1A. Furosemide @) Vancomycin [C. Naproxen (D. Rifampin ZE, D- penicillamine Qe (3 ‘Yhe final concentration of epinephrine in the standard Klein tumescent SS anesthesia is FA. 1:1,000. TB. 1:10,000. CC, 1:100,000. FD. 1:500,000. 1:1,000,000, fisherman develops a tender violaceous plaque on his hand. He most likely is infected with which of the following organisms?16 : hit Blood pressure should be monitored in patients with psoriasis treated with A, Bacillus anthracis TB. Pseudomonas mallei CC. Francisella tularensis (QD Erysipetothrix rhusiopathiae © An &-month old infant has diarrhea and a grusi eruption on the hands. feet, and perianal area five weeks aller being weaned ‘from breast-feeding. On examination, the infant is irritable and has diffuse hair loss. Which of the following nutrients is most likely deficient? A, bron (@) Zine MC. Copper MD. Selenium ME, Vitamin A tinate, 1D. methotrexate, ¥ 1A. calcipotriene. (B)cyclospori 5B. PUVA. Lerminally differentiated keratinc skin express C@involucrin, UD. (A. bullous pemphigoid anti keratin 14. E. faminin 5. \ -&) AQ The action spectrum for most photoailergens lies within which wavelength? ® “a 8 © QW wjury to the temporal branch of the A woman suffering from recurrent C1. The most appropriate course of « TA, teat avule episodes wilh subcutaneous epinepluine, MB. ucat prophylactically with epsilon aminoe: with danazol, D. treat prophylactically with prednisone. ™ internal malignancy. troviral drug inhibits protea ry Which ani IA, ddC (dideoxycytidine, zalcitabine, Hivid) B. ddl (dideoxyinosine, danosine, Videx) ! © Indinavir (Crixivan)! D. Lamivudine (3'FC) iE. Stavudine (d41, Zerit) ial nerve will result in iorelicad. eyebrow ptosis. C. tear formation. FE. inability to close the A, anesthesia of the side of the f eyebrow elevation. , increased eye. D A woman with breast carcinoma and cobblestone-like changes of the oral mucosa most likely has which of the following benign tumors? TA, Trichoepithelioma. MB. FibrofolliculonkeQ) Tri Cylindroma PE. Syringoma eee . 73 Botulism A exotoxin acts by 1A, preventing the binding of acetylcholine to pos neuromuscular junction. B. inhibiting synthesis of the neurotransmitter in post- ganglionic neurons. 1 C. down-regulating pos: motor nerves. SQ) inhibiting the rele: at the neuromuscular fiinctinn, neuromuscular junction. Gy the principal cause of morbidity and momtatity in patients with CRES Syndrome is CA, sepsis. "B. myocardial infarction. "©)pulmonary hypertension. FD. acute renal failure. ME. chronic renal failure, 25 A patient develops fever, a generalized pruritic, exfoliative erythroderma, epatosplenomegaly, and a generalized non-tender Iymphadenopathy. Two months earlier, she was started on carbamazepine (Tegretol) therapy for a seizure disorder. ‘he best alternative therapy would be TA. phenobarbital. (B. doxepin. 1 C. phenytoin. MD. benzodiazepine. XE) valproic acid. IB which histologic subtype of basal cell carcinoma has the highest risk of positive tumor margins afier simple excision? 1A. Morpheaform [B. Nodular fC. Superticial [D, Adenoid ¥E. Pigmented oF Potentially fatal administartion of terfenadine and vardiac arrhythmia can result from concomitantaspirin? > TA. Binding by aspirin to *@Meryhromycin. #'B. acetaminophen. 1 C. dapsone. | D. prednisone. ¥ E. insulin, , Sebum is secreted fA. only in response (o neutral sti hydration of the skin. ! ©)continuously onto response to dietary intake of lipids. FE. o1 ambient temperatures. The sign of Leser-'I relat is most commonly associated with 1@) seborrheic keratosis. !-B, trichilemmoma. 1-C. se TD. sclerotic fibroma. CE. angiofibroma. Roseola infantum is caused by (A. human herpes virus 8 (HHV-8). !() human herpes virus 6 (HHV-6). MC. parvovirus B19. MD. Coxsackie virus A16. PE. Epstein-Barr virus, ients who have Which of the following accounts for bleeding in igh-molecular-weight kininogen MB. Activation of prostacycline synthetase *(Q) Inactivation of phospholi Binding of aspirin to platelet membrane collagen receptors PE. Inhibition of fibrin cross-linking Which of the following equires an ption? milieu fi TA. Griseofulvin B, Fluconazole "Gitraconazole CD. Terbinafine FE. Erythromycin % 3 Anti-type IV collagen antibodies are expected to map to the roof of the ister in. fA, junctional epidermolysis bullosa letalis, 1713. localized epidermal builosa simplex. !C. generalized epidermolysis bullosa simplex. # dominant dystrophic epidermolysis bullosa. 7 E, epidermolysis bullosa herpetiformis.‘ely to be an adverse reaction to TA. gold. aquenil. D. predné PE. azathioprine GH Which of the ftle wing is true about unilateral laterothoracie exanth em? hovirus infection. ™B. Topical corticosteroids lead Adolescents are most often affected. >Q) The weeks, #E. The right side of the trink is