1.

Management options for solar urticaria include all of the

following except:

a. antihistamines

b. phototherapy

c. sunscreen

d. polypodium leucotome extract*

e. psoralen plus UVA phototherapy

2. Which T-cell subset is commonly found in Sezary

syndrome?

a. CD4+/CD7+

b. CD8+/CD7-

C. CD4-/CD7+

d. CD4+/CD7- *

e. CD8+/CD7+

3. The main cytokine secreted by Th1 CD8+ effector T-cells is:

a. IL-1

b. IL-2

c.IFN-gamma

d.IL-4

e. IL-5
4. This skin disease has been shown to be associated with
reduced Beta 2 defensin. The diagnosis is:

a. Atopic dermatitis*

b. Psoriasis

c. Lepromatous leprosy

d. Tuberculoid leprosy

e. Subacute cutaneous lupus erythematosus

5. Langerhans cell adhesion to keratinocytes is mediated by

what adhesion molecule?

a. E-cadherin
b. N-cadherin
c. Desmoglein 3
d. P-cadherin
e.B7
6. Which of the following cytokines are secreted from
keratinocytes?
a. IL-2
b.IL-3
c.IL-17
d.IL-22
e.IL-23
7. The formation of granulation tissue depends on the
presence of:
a. Neutrophils
b.Fibronectin
C.Collagen type I
d.Platelets
e.Collagen type IV
8. Which of the following dermal cells always express CD11c
and CD6?
a. Mononuclear phagocytic cells
b. Fibroblasts
c. Mast cells
d. Erythrocytes
e. Glomus cells
e. Dermatomyositis
9. IgE is produced by
a- Helper T cells
b- Suppressor T cells
c- Mast cells
d- B cells
e- Esinophile cells
 10. Which of the following disorders is primarily associated
with a monoclonal gammopathy of the IgA type?
a. Scleromyxedema
b. Scleredema
c. Necrobiotic xanthogranuloma
d. Schnitzler's syndrome
e. Pyoderma gangrenosusm
11.which of the following is the most common physical
Urticaria:-
• a. Cholinergic
• b. Dermatographism
• c. Acquagenic
• d. Pressure
• e. Cold Urticaria

• 12. Proteins in the alternate complement pathway include:

• a. Factor B
• b.properdin
• c. C3
• d. Factor B and properdin
• e .Factor B, properdin and C3
13. Active immunizations is induced by the administration of
all of the following except

a- Bacterial products

b- toxoides

c- Vaccines

d- Antitoxins

e- Attenuated pathogens

14. The radioimmunosorbent test (RIST) ia a technique use to

measure

a- Cellular antigens

b- Both antigen and antibody activity

c- Allergins in food

d- Specific IgE levels

e- Total IgE concentration

15. Regarding cytokines all the following statements are true
except:-

a)IL-4 stimulates B-lymphocyte proliferation.

b)IFN-alpha produced by macrophage.

c)TGF-beta stimulates wound healing.

d)TNF-alpha induces prostaglandin synthesis.

e)TNF-beta is elevated in UV radiation.

 • 16.The immunologic effects of UVR include all of the
following except:
a Alteration of Langerhans cell morphology
b Decrease in IL-1, IL-6, TNF-alpha
c Suppression of delayed-type hypersensitivity
d Alteration of lymphocyte population
e Alteration of Langerhans cell function

17. In solar urticaria wheals may be brought on by:

a UVA
b UVB
c UVC
d Visible light
e UVA, UVB and Visible light
18. Which of the following cell types induce susceptibility
to tumor growth?
a Suppressor T-cells
b NK cells
c Helper T-cells
d Mast cells
e Langerhans cells

19. As a result of ultraviolet radiation:

a There is mast cell degranulation and release of histamine
b Prostaglandins are increased
c Epidermal thickening occurs
d All of these answers are correct
e None of these answers are correct

20. The following compound exerts immunosuppressive

effects in the skin following exposure to UV-radiation:
a Cis-urocanic acid
b 7-dehydrocholesterol
c IL-12
d Delta aminolevulinic acid
e Amino-levulinic acid