Professional Documents
Culture Documents
Entrance of
Muscles Cervical thoracic duet into
contracting lymph vein
node
Right
lymphatic Thymus
duet gland
Muscles
relaxed Spleen
Red
bone
marrow
FIGURE 20.2 Normal and abnormal valves in venous and lymphatic vessels and their relation to backflow.
that propels the blood in the veins from the periphery back Lymphedema
chyli
toward the heart. Muscle contraction is the primary force As explained previously, the hydrostatic pressure that pushes
Inguinal
propelling both lymphatic and venous flow. Valves within the fluid out of the veins normally exceeds the osmotic pressure
lymph
vessels prevent backflow of the fluid, ensuring that the fluid keeping fluid inside node them. This causes fluids and proteins to
moves proximally toward the heart rather than being pushed flow into the interstitial space, producing lymph. To prevent this
toward the distal extremities (Fig. 20.2). lymph from accumulating, the lymphatic system acts as an
Lack of physical activity, dysfunction of the venous valves accessory channel that returns this fluid to the blood circulation.
caused by degeneration, or mechanical obstruction of the veins The lymphatic system consists of a large network of vessels and
by a tumor or inflammation can result in venous insufficiency nodes through which the lymphatic fluid flows. Lymphatic
and accumulation vessels are found in almost every area where there are blood
FIGURE 20.3of fluid incirculation.
Lymphatic the periphery.
(From Thibodeau GA, Patton KT: Anatomy and physiology, ed 6, St Louis, 2006, Mosby.)
vessels. Lymph flows along these vessels, passing through
numerous lymph nodes, to empty into the subclavian veins (Fig.
© Clinical Pearl 20.3). Lymph
congenital disorder nodesof the arelymphatic
concentrated
vessels,in whereas
the axillary, throat,
secondary
Q Clinical Pearl
groin, and paraaortic
lymphedema is caused by areassomewhere
otherthey filterorthe
disease lymph, remov-
dysfunction. An
Lack of physical activity, venous or lymphatic valve ing bacteria and other foreign particles. Thedisease,
lymphatic
Low serum albumin, lymphatic obstruction, abnormal example of primary lymphedema is Milroy in vessels
which aof
dysfunction, or venous obstruction all can result in the right
lymphatic vessel distribution, and reduced activity all can person hasarm terminate aplastic,
hypoplastic, in the right lymphatic
or varicose andduet and empty
incompetent
peripheral edema. into the right subclavian vein. The lymphatic vessels from
cause lymphedema. lymphatic vessels. Patients with primary lymphedema oftenall
otherbackflow
have areas terminate in the thoracic
in the lymphatic duetand
vessels, andthe empty
rate into the left
of protein
subclavian vein.
reabsorption across Once the lymphatic
vessel wallsfluidisreenters
usuallytheslowed.
circulatory
In
system, it is processed
The most common cause of venous insufficiency is secondary lymphedema, lymphatic flow is impaired by blockage by the kidneys along with other fluids,
Decreased levels
inflammation of the ofveins,plasma
known proteins cause fluid
as phlebitis. to
Phlebitis orwaste products,ofand
insufficiency theelectrolytes
lymphatics.and then eliminated.
accumulate
thickens theinvessel
the extravascular
walls and damagesspace because
the valves.theThickening
osmotic Fluidmost
The flows common into the causelymphatic
of secondary system lymphedema
because the
pressure
and lossthat normally of
of elasticity keeps fluid inwalls
the vessel the lymphatic
elevates the vessels and
hydrostatic concentra-is tion
worldwide of proteins
filariasis, a diseaseinside the lymphatic
characterized vesselsofis
by infestation
the veins in
pressure is the
reduced.
venousIf system,
the totalwhile leveldamage
of plasmato the generally higher than in the interstitial
valves the lymphatics and obstruction of the lymph vessels and
protein space. As with thenodes
veins,
decreases belowtotheflow
allows blood normal rangeproximal
in both of 6 to 8 and
g/dLdistal
or if the level
directions, byflow along
microscopic the lymphatic
filarial worms. vessels
Although in a
this proximal
disease is direction
common
ofrather
plasma
thanalbumin falls below
just proximally 3.3 g/dL,
through lymphedema
the veins, when the is muscles
likely independs
Asia, it on muscle
is rare in the activity,
Unitedsuch as walking
States, Australia,orand running,
Europe. which
In
tocontract
result. A(see
healthy
Fig. diet
20.2).andTheadequate proteinflow
retrograde reducesarethe the
absorption compresses
developedtheworld,vesselsinfection,
and their neoplasm,
valves and radiation
prevents backflow.
therapy,
required to keep
circulation plasma protein blood
of deoxygenated at an appropriate
out of thelevel. When
veins, Decreased
thus trauma, levelsarthritis,
surgery, of plasma proteins,
chronic venousparticularly
insufficiency, albumin;
and
lymphedema is caused
increasing pressure in thebyvenous
hypoproteinemia,
system if fluid this underlying
inflow mechanical obstruction of the lymphatics;
from the lipedema are the main causes of secondary lymphatic abnormal distribution
problem
arterial should
system be is addressed
unchanged.first Thetoelevated
prevent venous
further edema of lymphatic
pressure obstruction, 13 vessels or lymph nodes; and reduced activity all
with cancer treatment with lymph node removal or
formation and into
pushes fluid otherthe
adverse space, causing edema. If the radiation
consequences.
extravascular can resultbeing in most
reduced lymphatic
common. Otherflow
causes andof the formationinof
lymphedema
Lymphedema
limbs can be primary
are in a dependent position,or thesecondary,
edema willalthough it is
worsen further lymphedema.
the United States include mechanical obstruction of the vessels
usually
becausesecondary.
of increasedPrimary lymphedema
hydrostatic pressureis caused
caused byby gravity.
a by a tumor or inflammation, dysfunction of the valves
CHAPTER 20 • Compression 411
© Clinical Pearl
FIGURE 20.5 Venous stasis ulcer. Note the areas of darkened skin around FIGURE 20.6 Use of intermittent pneumatic compression to prevent deep vein
the ulcer caused by hemosiderin deposits. (From Cameron MH, Monroe LG: thrombosis (DVT) formation in a bedridden patient. (Courtesy DJO, Vista, CA.)
Physical rehabilitation: evidence-based examination, evalu- ation,
and intervention, St Louis, 2007, Saunders.)
reduced because slowly flowing blood can coagulate and form a Notably, although a 2010 systematic review based on four
thrombus. Therefore any intervention that increases the randomized controlled trials did not find that physical methods
circulatory rate may reduce this risk. Risk factors for DVT significantly reduced the frequency of DVT after acute stroke, 21
formation include older age, surgery, trauma, hospital or nursing the results of a later large, randomized controlled trial with
home confinement, cancer, central vein catheteriza- tion, almost 3000 patients published in 2013 found an absolute risk
transvenous pacemaker, prior superficial vein thrombosis, reduction of 3.6% for DVT and fewer deaths with IPC as
varicose veins, paralysis, use of oral contraceptives, pregnancy, compared to no IPC in patients who have had a stroke. 22
and hormone therapy.16 DVT formation is most common in Therefore some authors recommend IPC devices as an
immobilized patients, and more than 50% of all DVTs occur in alternative to anticoagulant medication for DVT prophylaxis
hospitalized patients and patients in nursing homes. Other when high bleeding risk prevents the use of anticoagulant
known risk factors account for 25% of DVTs, and 25% are of medication.23
unknown cause.17 Air flights lasting 8 hours or longer also increase the risk of
DVTs can cause a postthrombotic syndrome, characterized DVT formation in people with additional risk factors. 24 A 2006
by pain, swelling, and skin changes in the area of the thrombus, systematic review of 10 studies concluded that wearing
but a more significant health risk occurs if the thrombus compression stockings during flights lasting 7 hours or longer
becomes dislodged and blocks the blood supply to the lungs, substantially reduced the number of asymptomatic DVTs.10
causing a pulmonary embolus. Such blockage may cause Compression is thought primarily to reduce DVT formation
shortness of breath, respiratory failure, or death. Therefore by improving venous blood flow, thus reducing venous stasis
preventing the formation of DVTs in at-risk patients is and the opportunity for thrombus formation.25 Intermittent
imperative. compression may also inhibit tissue factor pathways that iniţiate
Various approaches including compression stockings, IPC, blood coagulation or may degrade thrombi by enhancing
calf muscle electrical stimulation, and anticoagulant medications fibrinolytic activity.26'29
reduce the risk of DVT formation. A 2014 Cochrane Collabora-
VENOUS STASIS ULCERS
tion systematic review and meta-analysis of 19 studies
A venous stasis ulcer is an area of tissue breakdown and
evaluating the efficacy of graded compression stockings for
necrosis that occurs in areas of impaired venous circulation (see
DVT preven- tion mostly in postoperative patients found that
Fig. 20.5). The exact mechanism by which poor venous
graded compression stockings used alone reduced the overall
circulation causes ulcers is still unknown, but it is thought that
risk of DVT formation from 21% in control groups to 9% in
increased venous pressure and deep venous reflux lead to
treated groups.1 Compression therapy is also probably effective
endovascular and inflammatory changes which provide a setting
for preventing postthrombotic syndrome.18 The length of the
for ulcer formation.30'32 Skin changes associated with
compression stocking is probably not important. A 2012
inflammation can then cause flbrosis, impaired wound healing,
systematic review comparing knee-length with thigh-length
and ulceration. It used to be thought that venous stasis ulcers
compression stockings for DVT prevention found insuficient
were caused by poor tissue oxygenation in areas of poor venous
evidence to recommend one over the other.19 IPC devices
circulation, but this is unlikely because it has been found that
applied to the foot and calf (Fig. 20.6) also reduce the incidence
tissue oxygen levels are generally in the normal range in areas of
of DVT formation in hospitalized patients. A 2005 meta-analysis
venous ulcers.29 Compression is the treatment of choice for
of 15 studies in 2270 surgical patients found that intermittent
treating and preventing the recurrence of venous stasis ulcers.
compression reduced the risk of DVT formation by 60%.20
414 PART VI • Mechanical Agents CHAPTER 20 • Compression 413
Compression can improve venous circulation. Improving CHF or cardiomyopathy, one must ensure that the increased
circulation may reduce adverse effects of poor venous flow, fluid load that could be placed on the heart by the shifting of
diminish the risk of vascular ulcer formation, and facilitate fluid from the periphery in response to treatment with
healing of previously formed ulcers.33,34 compression will not be detrimental to the patient. In such cases,
Compression increases the rate of healing of venous stasis the patient’s physician should always be consulted before
ulcers.33 Compression may facilitate healing by improving compression therapy is begun.
venous circulation, reducing venous pooling and reflux, All forms of compression are contraindicated in patients
improving tissue oxygenation, altering white cell adhesion, and with symptomatic heart failure (because of the risk of system
reducing edema. Multilayered compression (two or four layer) overload) and in patients with a thrombus (because of the risk of
is more effective for healing venous ulcers than single-layer dislodgment) and may not be appropriate if an arterial
compression, with systems including elastic components being revascularization has been performed on the involved limb. In
most effective. Consistently wearing compression stockings also addition, the clinician must evaluate for the presence and
reduces the likelihood of venous ulcer recurrence. 34 Wearing severity of arterial insufficiency before compressing a limb. This
compression stockings consistently is essential. Venous ulcers is most often determined by calculating the ankle-brachial
have been found to recur more often in patients who wear index (ABI). If the ABI is less than 0.6, all forms of static
compression stockings less often.35 IPC may be used to treat compression are contraindicated. If the ABI is greater than 0.8,
venous stasis ulcers that do not heal using other methods, and, at standard or full compression (30 to 40 mm Hg) may be used.
least in the short term, patient compliance may be higher with When the ABI is between 0.5 and 0.8, the compression pressure
this than with other methods of compression.36 should be reduced to between 23 mm Hg and 27 mm Hg. If the
patient also has neuropathy, careful monitor- ing is necessary
because they may fail to recognize symptoms of ischemia such
as pain, numbness, or tingling.
© Clinical Pearl
Particular care should be taken when applying and removing
Compression therapy is the cornerstone of treatment for compression bandages and garments to avoid trauma to healing
FIGURE 20.7 Compression for residual limb shaping. (Courtesy Silipos,
FIGURE 20.8stasis
venous Hypertrophic
ulcers. scarring. (From Cameron
Multilayered MH, Monroe
compression LG:
is more tissue or fragile skin. Details of contraindications and
Niagara Falls, NY.)
Physical rehabilitation: evidence-based examination,
effective than single-layer compression. evaluation, and precautions for the use of compression pumps are provided next.
intervention, St Louis, 2007, Saunders.)
CONTRAINDICATIONS FOR INTERMITTENT OR
CONTROL OFCOMPRESSION
SEQUENTIAL HYPERTROPHIC SCARRING
PUMPS
reducing the hyperproliferation
Compression that underlies
is generally contraindicated excessiveof
in the presence Hypertrophic scarring is a common complication of deep
arterial 45insufficiency because compression of the arterial vessels
scarring. ^burns and other extensive skin and soft tissue injuries. Normal
CONTRAINDICATIONS
mayWhen
further compression is applied
impair arterial flow,toaggravating
control hypertrophic
the condi- scar
tion. skin is pliable, is esthetically pleasing, and has clearly identifi-
formation,
However, treatment
surprisinglyis generally initiatedhasoncebeen
compression the new
foundepi-to for
ableIntermittent
layers, whereas or hypertrophic
Sequential scars are not pliable, have a
thelium
sometimeshas facilitate
formed and the ishealing
continued for 12insufficiency
of arterial months or longerulcers. Compression
raised and ridged Pumps appearance, and do not have clearly
until the scar hasfound
A meta-analysis reached
thatmaturity and isdemonstrated
some studies no longer growing.
improved • identifiable skin
Heart failure or layers
pulmonary (Fig.edema
20.8). Hypertrophic scars result in
Compression
wound healing canwith
be applied
IPC in with elastic
patients withbandages, self-adherent
severe peripheral artery • poor cosmesis
Recent or acuteandDVT, thethrombophlebitis,
development oforcontractures that may
pulmonary embolism
wraps,
diseasetubular
who were elastic cotton supports,
not candidates or custom-fit
for surgery. 37
elastic
It is possible that restrict ROM and function.
• Obstructed lymphatic or venous returnThe risk of hypertrophic scarring is
garments.
compression With any these
helped of these, the by
patients compression pressure
reducing chronic is
edema increased with delayed healing,
• Severe peripheral arterial disease a deep wound, repeated trauma,
maintained
that places at approximately
pressure 20 tovessels.
on the arterial 30 mmHowever,
Hg. It isbecause
recom-of • infection, or the
Acute local skinpresence
infection of a foreign
(e.g., cellulitis)body and in individuals
mended
the riskthat the compression
of further impairmentdevice be worn
of arterial flow23withto compression,
24 h/day to • with a genetic
Significant predisposition.
hypoproteinemia Hypertrophic
(protein scarring is most
levels <2 g/dL)
achieve maximum
compression not be 41used
shouldbenefit. Common
on most complications of this
patients with peripheral • common aroundorthe
Acute trauma sternum, upper back, and shoulders.
fracture
treatment include skin irritation, constriction of circulation, and
artery disease. Although
• Arterial many approaches, including surgery, pharma-
revascularization
restricted joint motion. ceuticals, passive stretch with positioning, massage, and silicone
RESIDUAL LIMB SHAPING AFTER AMPUTATION gel, are used to control the formation of hypertrophic scars,
Residual limb reduction and shaping are required to prepare for compression is the standard, first-line approach. Based on a
©funcţional
Clinical Pearlweight bearing on a prosthetic device. The residual systematic review of 28 articles, compression for at least 23 h/
limb must be shaped so that the prosthesis maintains its position Heart Failure
day with 20 toor30Pulmonary
mm Hg of Edema pressure is recommended to
To alignment
and control hypertrophic
and promotes scar formation,
weight bearing compression
on appropriate
producing Excessive
20 to 30 mm Hg ofonforce should be worn for 23 Although
decrease scar height dependent
edema of the and erythema. parts41ofMany
the body is a common
mechanisms have
structures. pressure unprotected bony prominences consequence
been proposed of CHF, to compression
explain the pumps effectsshould not be used toon
of compression
to 24 h/day for 12 months or longer.
should be avoided to promote comfort and function and to limit treat edema ofscarring.
hypertrophic this origin because the
Compression may shift of fluid
directly shapefromthe the
scar
the risk of tissue breakdown (Fig. 20.7).38 peripheral
tissue by to the central
acting as a mold circulation may increase
for the growth of newstress
tissue.onIt the
also
Both static and intermittent compression are used for limb failing organformation
decreases system. CHF resultsedema
of local from a and decrease in the collagen
improves ability
Contraindications and Precautions
shaping, although intermittent for the residual
compression can reduce ororientation.
efficiency Compression
of cardiac muscle may also contraction
improve and the subsequent
extracellular
limb in approximately
Externai Compression half the time required by other techniques, 39 decreased cardiac output.
matrix organization This increases
in hypertrophic venous
scars and pressure and
may increase
and acontraindications
Few temporary prosthesis may to
apply achieve ideal stump shaping
all compression even
devices; sodium and water
collagenase retention,
activity which
as a result of cause
increasededema.
skinTreating
temperature CHFor
more quickly
however, than with compression
when compression bandaging
is used to treat edema or or impaired
pneumatic requires
increaseddecreasing
releasetheofloadprostaglandin
on the heart, whereas
E2.8'42 compression
Alternatively,
40
compression.
circulation, When intermittent
the underlying cause ofcompression is used
these problems for be
should limb increases the cardiac
compression load by
may control scarincreasing
formationthe by amount
inducingoflocalfluid in
tissue
shaping, it is applied in conjunc- tion with an elastic
addressed before compression therapy is initiated. Compression bandage. the veins.43Thus
hypoxia or by compression
altering the tends to aggravate
release the underlying
and activity of matrix
Compression
therapy will be reduces residual
ineffective limb size because
and contraindicated in casesit where
Controls condition, resulting inthought
metalloproteinases worseningto beedema and potentially
involved causing 44
in wound healing.
postsurgical
edema is causededemaby and prevents
blockage stretching
of the of theorsoft
circulation, tissuesisby
if there other more serious side effects such as pulmonary
Compression has been shown to induce apoptosis (cell death) edema as
accumulated
active infection fluids.
or malignancy in the affected extremity. When CHF progresses. Peripheral edema caused by
and to regulate cytokine release in hypertrophic scars, thus CHF is usually
peripheral edema is caused by cardiovascular disease such as bilateral and symmetrical.
CHAPTER 20 • Compression 415
Pulmonary edema occurs with prolonged or severe CHF. It such cases cannot reduce the edema until the obstruction has
is the result of elevated lung capillary pressure, causing fluid to been removed. Lymphatic or venous return maybe obstructed by
leave the circulation and accumulate in alveolar air spaces in the a thrombus, radiation damage to the lymph nodes, an inguinal or
lungs. Compression is contraindicated when pulmonary edema abdominal tumor, or other masses. With parţial obstruction of
is present because compression increases the fluid load of the the vessels or complete occlusion of only a few of the vessels,
vascular system and pressure in the lung capillaries, potentially treatment with compression may enhance the functioning of
aggravating this serious medical condition. intact collateral vessels.
increase the moisture and temperature of the area encourage the ■ Ask the Patient A
■ of
growth Ask the Patient If a chronic skin infection is present,
microorganisms.
J
• “When did
Adverse your injury
Effects happen?” Compression^
of Externai
• “Do you
single-use have that
sleeves high blood
avoid pressure? If so, is it wellfrom one
cross-contamination ^The
«“Do you knowadverse
if a boneeffects
was broken?”
potentially of compression generally reiate
patientcontrolled
to anotherwith medication?”
or reinfection of the same patient may be used
■ Assess to aggravating a condition that is causing edema or is impairing
to apply intermittent compression.
^ « Resting blood pressure____________________________^ circulation if excessive pressure is used. When edema is the
result of heart,
Arterial kidney, or liver failure or circulatory obstruction,
Revascularization
■ Ask the Patient compression compression
Intermittent may aggravateisthecontraindicated
underlying condition. Also, if
after arterial
• "Do too much pressure is used, the compression device may cause
The you have any skin infections in the area to be treated?”
clinician should check with the patient’s physician for revascularization surgery because of the risk of occluding
soft tissue injury or act as a tourniquet, impairing arteriH
■ Assess
guidelines on blood pressure limits. arterial vessels and preventing blood from reaching the extremi-
• Inspect the skin for rashes, redness, or skin breakdown circulation
ties, leading and causing ischemia
to ischemia. If the patientand has
edemahad or compressing
recent arterial
Cancer indicating the possible presence of infection peripheral nerves.46,50
revascularization, If ischemia
elevation of theisextremity
prolonged, andimpaired
exercisehealing
may
Compression can increase circulation, which may disturb or be or used
tissue death canedema.
to decrease occur. When compression is effective in
dislodge metastatic tissue promoting metastasis or may improve reducing edema in an extremity, it is recommended that if this
tissue nutrition promoting tumor growth. Although no reports fluid accumulates at the proximal end of the extremity or where
' Ask the Patient
metastasis or accelerated tumor growth caused by the extremity attaches to the trunk, it should be mobilized using
have describedHypoproteinemia
Significant • “Have To
massage. youminimize
had surgery theonprobability
your arteries?”of adverse circulatory
the use of
Although compression,
peripheral edema itis is generallysymptom
a common recommended of severethat
■Assess
effects from treatment with compression, it is recommended that
compression not be
hypoproteinemia, whenapplied where aprotein
the serum tumor level
is present
is lessor than
when2 it
the°patient
Look for always
scars be thatmonitored closely
would indicate for undesired
vascular surgery,changes
^ in
is thought
g/dL, that an
reSulting increase
edema should in not
circulation
be treatedmaywith cause a tumor to
compression blood pressure
especially on theorlegs edema, particularly with the first application of
move orreturning
because grow more fluid rapidly. However,
to the vessels willcompression
further loweris the fre-
the treatment or with changes in treatment parameters.
quentlyprotein
serum used concentration,
to control lymphedema that results
potentially causing severe from
adverse the
treatment of breast
consequences, cancercardiac
including with mastectomy or radiation.
and immunological dysfunc- Application Techniques
Experts PRECAUTIONS FOR INTERMITTENT OR_____
in this
tion. field hypoproteinemia
Severe vary in their opinions can occurregarding
because theofsafety of this SEQUENTIAL
inadequate Compression can be applied in several
COMPRESSION PUMPS ways, depending on the
47 49
treatment
food andincreased
intake, the precautions
nutrientto losses,
be applied. ' Although
or increased some patients clinical presentation and the treatment goals. Static
nutrient
experts do notresulting
requirements considerfromthe anpresence or history
underlying disease.of malignancy to *compression
PRECAUTIONS can be applied with bandages or garments, whereas
contraindicate the use of compression, others recommend intermittent compression can be applied with electrical
ravoiding the use of compression in areas close to A
for Intermittent
the pneumatic pumps. or Sequential
Static compression can be used to help
■ Ask the
malignancy, and Patient
still others recommend not applying this type of control Compressionedema caused Pumps by venous or lymphatic dysfunction or
• “Have you
intervention untilrecently lost weight?”
the patient has been cancer-free for 5 years. In inflammation. • Impaired sensation Lymphedemaor mentationmanagement has focused on
• “Have you changed
general, most experts agree your diet?”
that the use of compression need not complete • Uncontrolled hypertension
decongestive therapy, which consists of manual
be • restricted
“Do you have any other
during the disease?”
time that patients are receiving lymphatic • Cancer drainage (MLD), compression, skin care, and light
Assess
chemotherapy, hormone therapy, or biological response exercise. • Superficial However,peripheral
basednerves
on current evidence, some recom-
• Checkfor
modifiers thetreatment
laboratory ofvalues section of the patient’s
their cancer. mendations suggest putting less emphasis on MLD and more on
chart for the serum protein level early diagnosis, weight control, exercise, and compression. The
v J optimal therapy
Impaired Sensation and or optimal
Mentation type of compression for
The
Ask use
the
of
Patient should be delayed until the patient’s Compression
compression lymphedemashould require be further
applied research
with and tocontinue
caution patients to
withbe
9
If edema results from the treatment of breast cancer: controversial. 52-56
impaired sensation or mentation because such patients may be
serum protein level is greater than 2 g/dL.
“Are you receiving chemotherapy, hormone therapy, or unable Static compression
to recognize can be used
or communicate whentopressure
form the shape of
is excessive
Acute Trauma
biological or Fracture
response modifiers for treatment of your cancer?” oramputated painful. residual limbs in preparation for the use of a
* Assess
Intermittent compression is contraindicated immediately after prosthetic device or to control scar formation after burn injury.
acute*Determine
trauma because how recently
compressionthe cancer diagnosis
may cause was motion
excessive Static and intermittent compression, used alone or together, can
' Ask the Patient ^
at the made
site of trauma, increasing bleeding, aggravating the acute be applied to help prevent the development of DVT in bedridden
• “Do you have normal feeling in this area?”
inflammation, or destabilizing an acute fracture.46 Such effects patients (see Fig. 20.6). Standard compression therapy for
■ Assess
can further damage the site of injury and can impair healing. venous ulcers generally involves bandaging, sometimes with
If the cause of edema isshouldunknown • Sensation in the area
Intermittent compression be and
usedtheforpatient has signs
treating post-of ^ aIPC, to control edema and promote ulcer healing and
Alertness and orientation____________________________^
cancer such
traumatic edema as only
recentafter
unexplained
the iniţial changes in body weight
acute inflammatory phaseor compression stockings to maintain edema control and prevent
constant
has passed, pain that does
bleeding has not change,
stopped, andtreatment
the area with compression ulcer recurrence.
is mechanically
stable. Static compression, as provided by stockings can
should be deferred until a follow-up evaluation that rule out
or wraps, Compression garments or low levels of intermittent
malignancy has been performed by a physician. COMPRESSION
compression may be used BANDAGING
if the patient has impaired sensation or
may be used immediately after acute trauma to prevent edema
Compression bandaging
mentation; however, such patients is recommended by the monitored
must be carefully Agency for
and reduce bleeding.
Superficial Peripheral NervesDirectly after an injury, static compression
Healthcare
for adverse Research
effects suchandasQuality
skin guidelines
irritation or for the treatment
aggravated edemaof
is frequently applied in conjunction with rest, ice, and elevation 13
Peroneal nerve palsy has been documented after the application caused lymphedema.
by constriction Early of in the intreatment
garments tight areas. of lymphedema,
to optimize the control of pain, edema, and50,51 inflammation.
of intermittent sequential compression. Significant weight compression bandages generally provide more effective edema
loss resulting in loss of fat and muscle mass around the peroneal control than compression garments, although upper extremity
Qnerves
Clinical predispose these nerves to injury from compression Uncontrolled
mayPearl funcţional statusHypertension
is worse.37 Therefore bandages are usually used
devices. When compression is applied over an area where there Compression
early in should
treatment tobereduce
applied with whereas
edema, caution garments
to patientsarewith
used
Immediately after acute trauma, static compression, often uncontrolled
is a superficial nerve, particularly in a patient with significant later to maintain edema control. hypertension because compression can further
in conjunction elevate blood pressure by increasing the vascular
restingfluid load.
weight loss, thewith rest, ice,
clinician should andmonitor
elevation, can be
closely forapplied
symptoms Compression bandages work by applying or working
to prevent edema and reduce bleeding. Do not apply Blood pressure should be monitored frequently while treating
of nerve compression, including distal changes in or loss of pressure or a combination of the two. Resting pressure is
intermittent compression immediately after acute trauma these patients, and treatment should be stopped if their blood
sensation or strength.
because this can aggravate bleeding or destabilize the site. pressure increases above the safe level determined by their
physician.
418 PART VI * Mechanical Agents
would be obtained with a compression garment or bandage. In time between 10 and 15 seconds. Usually, pressure is applied in
general, because a compression pump is used for only a number approximately a 3:1 ratio of inflation to deflation time; it is then
of hours each day, the patient should use a static compression adjusted if necessary according to the patients tolerance and
device between treatments with the pump to maintain the response.
reversal of edema produced by the pump. In patients with
chronic venous insufficiency and resulting edema and leg ulcers, Inflation Pressure
adding intermittent compression to the use of compression Inflation pressure, which is the maximum pressure during
stockings may accelerate wound healing64,65 and has been inflation time, is measured in millimeters of mercury (mm Hg).
recommended if compression stockings have been used Most units can deliver between 30 and 120 mm Hg of inflation
unsuccessfully for 6 months.65 Intermittent compression pressure. When a single-chamber sleeve is used to provide
generally is not used to decrease the formation of scar tissue intermittent compression, the chamber inflates to the maximum
because compression is required at all times for this effect. pressure and then deflates. When a multichamber sleeve is used
Despite ongoing controversy in the literature regarding the to provide sequential compression, the distal segment inflates
use of compression pumps for treatment of lymphedema, IPC is first to the maximum pressure, and then, as it deflates, the more
widely used for this indication, generally as a component of a proximal segments inflate sequentially, generally to a slightly
lymphedema management program that may include manual lower pressure. Some recommend that inflation pressure should
lymphatic drainage and compression bandaging or garments. 56 A not exceed diastolic blood pressure in the belief that higher
2012 systematic review of IPC for lymphedema concluded that pressures may impair arterial circula- tion; however, because the
IPC may provide additional benefit beyond that from only tissues of the body protect arterial vessels from collapse, higher
wearing compression garments.67 More recent studies also pressures may be used if this is necessary to achieve the desired
suggest that IPC, particularly high-pressure IPC to 120 mm Hg, 68 clinical outcome and does not cause pain, although close patient
can promote reduction of lymphedema, possibly by enhancing supervision is recommended when higher pressures are used. For
formation of fluid channels in the tissue. 69 Further study is all indications, inflation pressure is generally between 30 and 80
needed on the treatment of lymphedema with pneumatic mm Hg and frequently is just below the patients diastolic blood
compression.70,71 pressure. Because venous pressure is usually lower in the upper
extremi- ties than in the lower extremities, the lower end of the
pressure range, 30 to 60 mm Hg, is generally used for the upper
PARAMETERS FOR INTERMITTENT extremities, and the higher end of the range, 40 to 80 mm Hg, is
PNEUMATIC COMPRESSION PUMPING generally used for the lower extremities. Lower pressures are
Inflation and Deflation Times generally recommended for residual limb reduction and shaping
Inflation time is the period during which the compression sleeve and to treat posttraumatic edema rather than the problems caused
is being inflated or is at the maximal inflation pressure; deflation by venous insufficiency.
time is the period during which the compression sleeve is being The ideal amount of pressure for the treatment of edema due
deflated or is fully deflated. For the treatment of edema or to venous or lymphatic insufficiency is controversial. Clinical
venous stasis ulcers or for DVT prevention, the inflation time is practice guidelines for treatment of lymphedema indicate that
generally between 80 and 100 seconds, and the deflation time is lower pressures, 30 to 60 mm Hg, are safer and may still be
generally between 25 and 50 seconds to allow for venous effective for this condition,66'73 but a recent study found that
refilling after compression. No difference in volume reduction adding IPC at 120 mm Hg to manual lymphatic drainage and
was found in patients with upper extremity lymphedema between multilayer bandaging was significantly more effective for
90-second inflation/90-second deflation compared with 45- controlling lower extremity edema than adding IPC at 60 mm Hg
second inflation/ 15-second deflation. 72 For residual limb or not adding IPC at all. 68 This may be in part because the
reduction, these periods are generally shorter, with inflation time pressure achieved in the tissue fluid is lower
between 40 and 60 seconds and deflation
424 PART VI • Mechanicai Agents CHAPTER 20 • Compression 425
Continued
430 PART VI • Mechanical Agents
CHAPTER 20 • Compression 431