PMID- 38466132

OWN - NLM
STAT- MEDLINE
DCOM- 20240312
LR - 20240312
IS - 1364-6893 (Electronic)
IS - 0144-3615 (Linking)
VI - 44
IP - 1
DP - 2024 Dec
TI - Effects of vaginal dilation therapy on vaginal length, vaginal stenosis,
vaginal
elasticity and sexual function of cervical cancer survivors.
PG - 2317387
LID - 10.1080/01443615.2024.2317387 [doi]
AB - BACKGROUND: Cervical cancer survivors can experience vaginal length
shortening,
vaginal stenosis, vaginal elasticity deterioration, sexual frequency
reduction
and sexual dysfunction. This prospective, uncontrolled, monocentric clinical
interventional study aimed to evaluate the effect of vaginal dilation therapy
on
vaginal condition and sexual function of cervical cancer survivors who had
not
received timely vaginal dilation. METHODS: A total of 139 patients completed
the
study. They received 6 months of vaginal dilation therapy. We evaluated their
vaginal elasticity, vaginal diameter, vaginal length and sexual function
before
and after vaginal dilation therapy. Their vaginal conditions were evaluated
by
customised vaginal moulds, and the sexual function was assessed by female
sexual
function index. The SPSS 25 software was used to analyse all the data.
RESULTS:
Age, vaginal diameter and sexual intercourse frequency before diagnosis were
significantly associated with female sexual dysfunction of the patients after
cancer treatment. Vaginal dilation therapy improved vaginal stenosis, vaginal
length and sexual function in all the patients; however, the vaginal
elasticity
and incidence of sexual dysfunction did not improve significantly. Sexual
intercourse frequency before diagnosis, vaginal elasticity, time interval
from
last treatment and treatment modalities were significantly associated with
the
change in female sexual function index score before and after vaginal
dilation
therapy. Patients with a time interval from the last treatment less than
24 months or those who had moderate or good vaginal elasticity, benefitted
more
from vaginal dilatation therapy. CONCLUSIONS: Cervical cancer survivors who
had
not received timely vaginal dilation still benefitted from vaginal dilation
therapy, irrespective of the treatment methods they received. Moreover,
vaginal
dilation therapy should be performed as early as possible after cervical
cancer
treatment.
FAU - Lin, Yu-Xuan
AU - Lin YX
AD - Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Beijing
Maternal and Child Health Care Hospital, Capital Medical University, Beijing,
China.
FAU - Zhao, Fei-Fei
AU - Zhao FF
AD - Department of Gynecology and Obstetrics, Beijing Fuxing Hospital, Capital
Medical
University, Beijing, China.
FAU - Kong, Wei-Min
AU - Kong WM
AUID- ORCID: 0000-0002-4429-3242
AD - Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Beijing
Maternal and Child Health Care Hospital, Capital Medical University, Beijing,
China.
LA - eng
PT - Journal Article
DEP - 20240311
PL - England
TA - J Obstet Gynaecol
JT - Journal of obstetrics and gynaecology : the journal of the Institute of
Obstetrics and Gynaecology
JID - 8309140
SB - IM
MH - Humans
MH - Female
MH - *Uterine Cervical Neoplasms/therapy
MH - *Cancer Survivors
MH - Vagina
MH - Constriction, Pathologic/etiology/therapy
MH - Dilatation/adverse effects
MH - Prospective Studies
MH - Elasticity
OAB - Cervical cancer survivors can experience vaginal condition deterioration and
sexual dysfunction after treatment. Vaginal dilation can help improve vaginal
stenosis, vaginal length and sexual function of these patients. However, some
medical institutions in China do not provide timely vaginal dilation for this
population. This study aimed to explore whether vaginal dilation was still
effective for cervical cancer survivors who had not received timely vaginal
dilation. The results showed that these patients still benefitted from
vaginal
dilation, irrespective of the treatment methods they received. Patients with
a
time interval from the last treatment less than 24 months or those who had
moderate or good vaginal elasticity, benefitted more from vaginal dilation.
The
findings of the study is an indication to developing countries that more
attention should be given to sexual issue of cervical cancer survivors in
clinical practice, and vaginal dilation therapy should be performed promptly
after treatment.
OABL- eng
OTO - NOTNLM
OT - Cervical cancer
OT - female sexual dysfunction
OT - sexual function
OT - vaginal dilation therapy
EDAT- 2024/03/11 12:43
MHDA- 2024/03/12 06:43
CRDT- 2024/03/11 10:23
PHST- 2024/03/12 06:43 [medline]
PHST- 2024/03/11 12:43 [pubmed]
PHST- 2024/03/11 10:23 [entrez]
AID - 10.1080/01443615.2024.2317387 [doi]
PST - ppublish
SO - J Obstet Gynaecol. 2024 Dec;44(1):2317387. doi:
10.1080/01443615.2024.2317387.
Epub 2024 Mar 11.