Majalah Farmasetika, 6 (1) 2021, 10-22
idol org/10.24198/mfarmasetika.v6it.27420
‘Arikel Review
Stabilisasi Tablet Yang Mengandung Zat Aktif Bersifat Higroskopis
Fits Nujanah, Sriwidodo’, Bambang Nurhaci?
*Departemen Farmasetika dan Teknologi Farmasi, Fakultas Farmasi, Universitas Padjadjaran,
‘Jalinangor 453632
SDepartemen Teknolog! industri Pangan Fakultas Teknolog| Industri Pertanian, Universitas Padjajaran,
Jatinangor 45363,
e-mail firi16004@mail unpad.ac.id
(Submit 1615/2020, Revisi 2176/2020, Diterima 03/08/2020)
Rute pemberian obat oral merupakan rute yang paling banyak digunakan untuk obat
yang berefek secara sistemik, setidaknya 80% obat yang menghasilkan efek sistemik
diberikan secara oral (!|. Salah satu bentuk sediaan padat oral adalah tablet. Tablet
merupakan bentuk sediaan yang memiliki banyak keuntungan diantaranya lebih mudah
untuk dikonsumsi, biaya produksi yang lebih rendah, serta stabil dalam
penyimpanannyal, Tablet memberikan kenyamanan dan keamanan untuk pemberian
zat aktif farmasi (API) dengan stabilitas fisikokimia yang baik dan memberikan dosis
yang akurat dibandingkan dengan bentuk sediaan larutan
LiverTox
Clinical and Research information on Drug-induced Liver Injury
Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseas
2012,
‘Copynght and Permissions
EN Tar ¢
Codeine (koe” deen) is a natural alkaloid derived from resin extracts from the seeds of the opium poppy, Papaver
somniferum. Codeine has opiate-like analgesic effects, but is much less potent than morphine. Codeine, however. is
‘well absorbed orally and is Jess likely to cause serious respiratory depression than morphine. Codeine has been used
in clinical medicine for more than a century and is currently approved for use in the United States as an oral analgesic
for mild-to-moderate pain and, in low doses, as an antitussive for suppression of nonproductive cough. Codeine isBasil V. Peechakara; Jack G. Tharp; Mohit Gupta,
* Author Information and Affiliations.
Authors
ww
Basil V. Peechakara; Jack G. Tharp!; Mohit Gupta”
STATPEARLS
SouTenT TE ne Affiliations,
Univ of Mississippi Medical Center
2 Cleveland Clinic Foundation
February 13, 2023,
Codeine is a medication used in the management and treatment of chronic pain. It is in the opioid class of
medications. This activity outlines the indications, action, and contraindications for codeine as a valuable agent in
treating chronic pain and off-label use in cough, persistent diarthea, and restless leg syndrome. In addition, this
activity will highlight the mechanism of aetion, adverse event profile, off-label uses, dosing, pharmacodynamics.
pharmacokinetics, monitoring, toxicity, and relevant interactions pertinent for interprofessional team members in.
‘eating patients with clronie pein and related conditions.
DIPONEGORO MEDICAL JOURNAL
Goad ipnes)
Volume 9, Nomor 2, Maret 20
‘THE EFFECT OF PARACETAMOL AND CODEINE ANALGESIC COMBINATION
ON SERUM GLUTAMIC OXALOACETATE TRANSAMINASE LEVELS IN MALE
WISTAR RATS
Rona Ayu Hanifah ', Farah Hendara Ningrum ?, Erwin Kresnoadi , Satrio Adi Wicaksono ?
Undergraduate Student, Faculty of Medicine, Diponcgoro Univesity
‘Departement of Radiology, Faulty of Medicine, Diponegoro University
"Department of Anesthesiology and Intensive Cae, Faculty of Medi, Diponegoro Universiy
*Comesponding email = sttriowicalsono(@fkandip.acidChemical Disinfection of Hard Surfaces —
Household, Industrial and Institutional Settings
Edward Fu,... Diane Boesenberg, in
Pee ey
Science
Handbook for Cleaning/Decontamination of Surfaces, 2007
5.6 Alcohols
Ethyl alcohol, iso-propyl alcohol and n-propyl alcohol possess very good
disinfectant properties in the range of 60-90% solutions with water. They
are considered intermediate-level disinfectants, effective against vegetative
bacteria, enveloped viruses, and some fungi and mycobacteria, including M.
tuberculosis. Alcohols are believed to function by denaturing proteins, which
is dependent on the relative amounts of alcohol and water [22].
Zoe Clarke, in xPharm: The Comprehensive Pharmacology Reference, 2007
Saeed
ala memebers § Ethanol, or ethyl alcohol, is a central nervous system depressant. Although it
has no unique medicinal value, it is regularly consumed for recreational
purposes, Ethanol intake is often referred to in terms of units, with 1 unit
being equal to 8 grams of ethanol, the amount contained in 1/2 pint of
normal strength beer, 1 standard glass of wine, or 1 measure of spirits.
. Toxic Encephalopathies I: Cortical and Mixed
——
Encephalopathies
CLINIGAL |v): Eicher, in clinical Neurotoxicology, 2009
NEUROTOXICOLOGY
Ethanol
Ethyl alcohol or ethanol (EtOH) is the most common organic solvent to
which Americans are exposed. Its acute effects are well recognized and
obviously occur most often in the setting of recreational ingestion of beer,
's, EtOH is also present in many household products,
pharmaceuticals, and industrial solvents. The acute encephalopathy of EtOHPyrolysis of Alcohols and Phenols
Serban C, Moldoveanu, in Pyrolysis of Organic Molecules (Second Edition), 2019
ef
Organic Molecules ENeouh)
Glycerin (glycerol or propane-1,2,3-triol) is a compound widespread in
nature either in free form or, more frequently, as an ester (glycerides).
Glycerin can be considered a sugar alcohol formed by hydrogenation from
~ glycerin aldehyde (a Cy monosaccharide). Large quantities of glycerin are
synthesized from epichlorhydrin and are generated as a byproduct in soap
making and biodiesel production, Glycerin is used as a humectant in the
ss food, beverage, and tobacco industries as well as a solvent, a sweetener, and
a thickening agent.
PASSN 2746-5241
JAM: Jurmal Abdi Masyarakat Vol, 4, No.1, Mei
2023, Hal (92-95)
ai gpindha Webby wdhacid
FACTS OR HOAXES OF ALL DANGEROUS SYR
Sayyidah*, Humaira Fadhilah, Wafa, Neneng Sri Purwaningsih,
Melizsa, Beny Maulana Satria, Suny Koswara Rahajeng, Mé
‘Oktavia, Dimas Wijanarko
‘Ske Wi Ema Hass Tings, Ko Tangs Sa, 37, nos
Syrup is an oral solution containing sucrose or other sugars of high grade (simplex
syrup is a syrup that is almost saturated with sucrose). The sucrose content in
syrup is 64-66%, unless otherwise stated. In general, syrups are divided into 2
types, namely Non Medicate Syrup / Flavored Vehicle Syrup (Such as piperazina
citrate syrup, isoniazid syrup). Non Medicate Syrup is a syrup preparation that
does not contain medicinal ingredients, but only contains sugar, flavorings,
preservatives and dves while Medicinal Svrun contains medicinal ingredients /Artikel Penelitian
FORMULASI DAN UJI STABILITAS SEDIAAN SIRUP ANTI ALERGI
DENGAN BAHAN AKTIF CHLORPHENIRAMIN MALEAT (CTM)
Djelang Zainuddin Fickri, S. Farm., M. Farm.Klin., Apt.
Abstrak: Scdiaan Sirup merupakan sediaan cair yang berupa larutan yang ditandai
dengan rasa manis dengan kandungan sakrosa tidak kurang dari 64% dan tidak lebih dari
66,0. Pada penelitian formulasi ini digunakan bahan aktif Chlorpheniramin (CTM) yang