Anileridine

Clinical data

AHFS/Drugs.com Monograph

Routes of Tablets, injection

administration

ATC code  N01AH05 (WHO)

Legal status

Legal status  AU: S8 (Controlled)

 CA: ℞-only

 US: Schedule II

Pharmacokinetic data

Protein binding > 95%

Metabolism Hepatic

Identifiers

IUPAC name

CAS Number  144-14-9

PubChem CID  8944

DrugBank  DB00913

ChemSpider  8600

UNII  71Q1A3O279

KEGG  D02941

ChEBI  CHEBI:61203

ChEMBL  ChEMBL1201347

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Chemical and physical data

Formula C22H28N2O2

Molar mass 352.47 g/mol

3D model  Interactive image

(JSmol)

Melting point 83 °C (181.4 °F)

SMILES

InChI

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Articles on Anileridine in N Eng J Med, Lancet,

BMJ

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Guidelines / Policies / Govt

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Anileridine

NICE Guidance on Anileridine

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International

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview
Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of
the piperidine class of analgesic agents developed by Merck & Co. in the 1950s. It differs
from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-
aminophenethyl group, which increases its analgesic activity.
Anileridine is no longer manufactured in the US or Canada.[1]

Administration
As tablets or injection.[2]

Pharmacokinetics
Anileridine usually takes effect within 15 minutes of either oral or intravenous
administration, and lasts 2–3 hours.[3] It is mostly metabolized by the liver.