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Parkinson’s is a neuro-degenerative

disease where the dopamine producing


cells deplete.

Dopamine is a hormone that maintains


chemical balance in neurological pathways.

When there isn’t enough of it, the


balance tilts- PD patients will most likely
struggle with motor tasks.
PD already has some treatments.

Levodopa, the most effective treatment

Leads to negative effects after 5 years of


use.

Surgical options available like lesioning


or DBS.

Must be repeated and persistent.


Stem cells have been considered as a
treatment for PD since the 60s

In the 80s, many trials were run. None


showed clear results.

In recent years, the clinical trial


outcomes have improved.

Specifically the one conducted by


Bluerock Therapeutics.

Their treatment- bemdaneprocel-


showed and continued to show positive
results even 18 months after treatment.

Advantages
 this procedure is predicted to have
positive effects on PD patients for even
longer than Levodopa
 This treatment will help 10 million
patients with PD,
 Revolutionise scientific perspectives on
regenerative medicine for other
diseases
Disadvantages:
 ESCs are the best type of stem cell for
these treatments
 Have a lot of controversy around the
ethical issues.
 Is it really worth destroying a human
embryo for research purposes?
 Experimental- costs a lot of money for
both the patients’ families and the
hospital whose resources go towards
intricate post operative care and
monitoring
In conclusion, stem cells may
eventually become a life changing way
for patients to recover from PD, after
the difficulties are overcome.

With the advancement of science,


people can regain control over their
bodies and return to their old ways.

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