PRIMEASIA UNIVERSITY

A Mission With a Vision

ASSINGMENT ON
Good Pharmaceutical Practices On Compounding And Dispensing

Course Code: PHR 2202

Course Title : Pharmaceutics II

Submitted To Submitted By
Rabeya Jafrin Mou Tabassum Rajoana Tumpa
Lecturer
Department of Pharmacy ID: 201 052 032
Primeasia University
Department of Pharmacy

Primeasia University

Date of Submission:19-12-2021
 Good Pharmaceutical Practices On
Compounding And Dispensing

Compounding
Drug compounding is often regarded as the process of combining, mixing, or altering
ingredients to create a medication tailored to the needs of an individual patient. Compounding
includes the combining of two or more drugs. compounding pharmacy is an important ally in
providing access to discontinued or hard to find medications.

Dispensing
Dispensing is the provision of drugs or medicines as set out properly on a lawful prescription.
The dispensing of drugs should be carried out by trained pharmacists. Dispensing is the
provision of drugs or medicines as set out properly on a lawful prescription. Dispensing is one of
the vital elements of the rational use of medicines.

Good Pharmaceutical Practice means the standards that are generally accepted by the
pharmaceutical community as constituting appropriate and adequate care. GPP is the practice
of pharmacy that responds to the needs of the people who use the pharmacists' services to
provide optimal, evidence-based care. The purpose of this standard is to provide guidelines to
pharmacists and PSP when medicines are dispensed or re-dispensed as individual unit doses for
a particular patient, to facilitate administration with the aim of improving adherence to
therapy.

Good Compounding Practice (GCP)

Good Compounding Practices (GCP) means the minimum standards for methods used in, and
facilities or controls used for, compounding a drug to ensure that the drug has the identity and
strength and meets the quality and purity characteristics it is represented to possess. Many
patients need drug dosages or strengths that are not commercially available. So, pharmacists
can compound them for their physicians’ and patients’ use. So good compounding practice is an
important integral part of pharmacy practice and is essential to the provision of health care.

Practices Compounding
Preparatory

• Judging the suitability of the prescription in terms of its safety and intended use and the dose
for the patient.

• Performing the calculations to determine the quantities of the ingredients needed.

• Selecting the proper equipment and making sure it is clean.

• Donning the proper attire and washing hands.

• Cleaning the compounding area and the equipment, if necessary.

• Assembling all the necessary materials and ingredients to compound and package the
prescription.

Regulation

In contrast with the practice today, regulatory bodies exist for pharmacy practice and
compounding. One of their jobs is to produce regulation, uniform standards, and guidelines to
guarantee that only the highest quality products are prepared for the patients and to ensure
patient health and safety. Regulatory bodies are in charge of creating regulations and making
existing regulations striken so as to ensure the safety of patients.

Sign-Off
Signing and dating the prescription, affirming that all of the indicated procedures were carried
out to ensure uniformity, identity, strength, quantity, and purity.
Final Check

Checking, as indicated, the weight variation, adequacy of mixing, clarity, odor, color,
consistency, and pH.

Labelling

Labelling should be done according to state and federal regulations. labelling information
includes the:

 generic or chemical names of the active ingredients,

 strength or quantity,
 pharmacy lot number,
 beyond-use date,
 any special storage requirements.

Personalizing compounding

Compounding has further evolved into more innovative practices, such as customized dosages,
alternative drug delivery systems and production of allergen-free formulations.

Good Dispensing Practice (GDP)

It refers to the delivery of the correct medicine to the right patient, in the required dosage and
quantities, in the package that maintains acceptable potency and quality for the specified
period, clear medicine information counseling and appropriate follow up.

Preparing the Medicine

 Selecting the Medicines
 Extemporaneous Preparation/ Compounding
 All dispensed medicines should be labelled according to the requirement stated by law.
It is advisable for labels to be printed. If handwritten, it should be neat and legible with
clear instructions on use.
 Check the prescription and the filled medicines to ensure that the filled medicines
correlate with the prescription.
  Proper record keeping is an essential part of dispensing as it facilitates good
management and monitoring of services provided.

Screening of Prescription
• On receiving a prescription, it should be screened and validated to ensure that it is for

the correct patient and it complies with the requirements in the Poisons Act.

• Interpreting the Prescription Order

• Handling Prescriptions which Require Clarification

• Handling Prescriptions in A Stock-Out Situation

supply of medicine
When dispensing the medicines, ensure the 5Rs:

 Right Patient
 Right Medicine
 Right Dose
 Right Route
 Right Time

Maintaining Pharmaceutical Stocks

Supply of Medicines on Long-term Prescription

Delivery of Repeat Medicines by Post

A safe, clean and organised working environment provides the basis for good dispensing
practice. The dispensing environment includes-

 Qualified / trained staff

 Appropriate physical surroundings
 Adequate shelving and storage areas
 Proper work surfaces Suitable equipment
 Necessary packaging materials.
Conclusion
Pharmaceutical Compounding and Dispensing is a comprehensive guide to producing
extemporaneous formulations safely and effectively. This is a modern, detailed and practical
book on the theory and practice of extemporaneous compounding and dispensing. Ensuring
that the supply of medicines is within the law. Ensuring that the medicines prescribed to
patients are suitable. Advising patients about medicines, including how to take them, what
reactions may occur and answering patient’s questions.