disease MCQ and SEQ Classification of arrhythmias Cardiac arrhythmias are defined as abnormalities of cardiac rhythm • Based on the heart rate • Tachyarrhythmia- Heart rate > 100/min • Bradyarrhythmia- Heart rate < 60/min • Based on the site of onset • Supraventricular • Supraventricular tachyarrhythmias arise from the cardiac tissue above the ventricles – Narrow QRS complexes • Ventricular • These arrhythmias arise from ventricular cardiac tissue – Broad QRS complexes Q1 - AF • T/F regarding atrial fibrillation • Occurs as a consequence of acute alcohol excess • The incidence increases with age • A ‘saw tooth’ P wave in the ECG is characteristic • Causes a completely irregular pulse which regularizes with exercise • Increases the risk of stroke and TIA AF Q2 - AF • T/F regarding atrial fibrillation • In stable patients with AF, immediate electrical cardioversion is the preferred treatment option • Digoxin the preferred agent for control of the ventricular rate • All patients with AF should be commenced on anticoagulation • Aspirin is an effective alternative for oral anticoagulation in patients with AF to reduce the risk of stroke and TIA • A long-term rhythm control strategy has a better outcome than rate control combined with anticoagulation Best response Q1. • A 65-year-old female presents with a history of fatigue and palpitations and shortness of breath for 4 hours duration. On examination she is vomiting, and is noted to have a slight tremor, some lid lag and has an irregularly irregular pulse of 140 per minute, with extensive bi basal crepitations. ECG confirms atrial fibrillation with a rate of approximately 130 per minute. Thyroid function tests show: Free T4 31.8 pmol/l (9-22) TSH 0.05 mu/l (0.5-4.5) • Which of the following is the most appropriate initial treatment for this patient? • Anticoagulation • DC cardioversion • IV amiodarone • IV digoxin • IV Metoprolol Choice of rate control Best response Q2. • An 80-year-old woman was admitted to the ward with dizziness. Cardiac monitoring initially revealed atrial fibrillation with rapid ventricular response. Her ventricular rate was controlled with beta blocker. An echocardiogram revealed an enlarged left atrium and an ejection fraction of 50%. No evidence of diastolic heart dysfunction was noted. She is now asymptomatic, with blood pressure 130/80 mmHg, heart rhythm irregularly irregular, and heart rate around 80 beats/min. Which of the following is the best management strategy of this patient's arrhythmia?
• Electrical cardioversion plus prolonged anticoagulation
• Electrical cardioversion without anticoagulation • Chemical cardioversion plus prolonged anticoagulation • Chemical cardioversion without anticoagulation • Continued rate control plus prolonged anticoagulation. Q3. SVT • T/F regarding paroxysmal supraventricular tachycardia • This is most often due to an accessory pathway connecting the atria and the ventricles • Causes a broad complex tachycardia • Vagal manoeuvres are contraindicated • Intravenous calcium channel blockers are first line therapy • Flecainide can be used for rate control in patients with structural heart disease Q4. VT vs. SVT • Which of the following suggest a VT than SVT? • Broad QRS complex • Presence of capture beats • Irregular rhythm • AV dissociation • Concordance of voltage complexes in the precordial leads Q5. – Heart blocks • T/F regarding complete heart block • Irregular cannon ‘a’ waves can be seen on the ECG • Presents with syncopal attacks • CHB with a narrow ventricular escape rhythm has a poor prognosis • Dissociation of P waves and QRS complexes on ECG • Varying intensity of the first heart sound AV blocks ECG CHB Escape rhythms • Better prognosis with narrower QRS Bradycardia management Q6. Pericardial disease • T/F regarding acute pericarditis • Can occur due to coxsackie viruses • Causes chest pain, relieved in the seated position • PR segment depression is seen on the ECG • Colchicine is used in the treatment • Hemorrhagic pericardial effusions are seen in patients with uremic pericarditis Q7. Pericardial disease • T/F regarding pericardial disease • Pulsus paradoxus is seen in large pericardial effusions • Electrical alternans on the ECG is seen in patients with cardiac tamponade • Tuberculosis is a recognized cause of constrictive pericarditis • Kussmaul’s sign is a feature seen in patients with constrictive pericarditis • Pericardiocentesis is the treatment of choice for patients with cardiac tamponade Kussmaul’s sign in CP • Increase in venous distension in the neck with inspiration • Rigid pericardium – negative IT pressure not transmitted to heart • No inspiratory increase in RV filling • Venous backpressure Video • https://www.youtube.com/watch?v=795GGACswTA • https://www.facebook.com/DrShankul/videos/429316941029297/ A 60-year-old male with a history of hypertension presented with recurrent episodes of palpitations and progressive shortness of breath over a period of 3 months. On examination he had an irregularly irregular pulse with a heart rate of 140/min, BP – 120/70, a pansystolic murmur in the mitral area which
SEQ radiated to the axilla, bilateral lower limb edema and a few bilateral basal inspiratory crackles on lung auscultation. The ECG recorded is given below.
1. What is the ECG diagnosis? (10 marks)
2. Give 2 reasons for your answer in (1). (10 marks) 3. Outline the initial management of this patient (20 marks) Management • Stabilization and cardiac monitor • Rate control • Diuretics • Anticoagulation • The patient subsequently underwent an echocardiogram and was diagnosed to have mixed mitral valve disease with severe MR and mild MS. He was started on warfarin and registered for valve replacement surgery. • Describe the mechanism of action of warfarin and the rationale to administer it in this patient (20 marks) • Outline the important advice you will give this patient regarding warfarin (20 marks) Warfarin - MOA Warfarin patient advice • Indication • How to take – same time every day • Adverse effects • Interactions • Food • Alcohol • Missed doses • Monitoring and INR