Professional Documents
Culture Documents
Troubleshooting Guide
for the multiFiltrate
Contents Balancing error on scales
NO
YES
This Guide has been produced by Fresenius Medical Care to help you get the best Is the filtrate outflow Unclamp it and press start/reset key
out of the multiFiltrate machine. This Guide is intended as a support tool and will line clamped? to recommence treatment.
not replace the operating manual or the judgement and experience of the nurse and NO
the attending physician. Enter bag change menu. Is the YES Was a bag with fluid on the scale during
effluent scale value negative after self test? If yes, the TARE weight has
a bag change? been set to include the volume
Please read this Guide and familiarise yourself with the content. This Guide contains
contained in the bag during set-up. This
information on how to resolve some of the most common machine alarms. This Are scales I and
cannot be corrected. End treatment and
ll affected?
Guide is intended to be kept with the multiFiltrate machine so it is always to hand. NO re-start with new circuit.
Decisions concerning specific treatments for patients are within the sole
responsibility of the attending physician and nurse. YES Examine the scale pans, are they seated NO Access bag change menu, manually
correctly on the scale plates (are the remove and replace scale pans to
plates recessed and flat or are they tilted)? have them seated correctly on the
YES scale plates. Press start/reset key to
There might be a technical fault with recommence treatment.
the machine. Please contact the
Technical Services Department.
1
Arterial pressure too low Arterial pressure too high
YES YES
Is the patient catheter kinked Unkink catheter, press start/reset to
at the patient end? recommence treatment. Consider the patient's condition. Are there
patient factors that are creating a positive Take necessary action.
NO pressure at the access site?
NO Manipulate catheter. Press start/reset key until
Is the access catheter in the correct
flow is re-established. Consider swapping NO
position to allow adequate flow?
over lines if difficult to re-establish flows. YES Stop infusions, or YES
YES reduce infusion rate.
Are there any infusions being
NO Press start/reset
Internal failure of arterial pressure sensor. administered before the blood pump Continue treatment.
Press start/reset key. Clamp and disconnect key. Observe effect
Stop treatment. Washback patient blood. (To the two additive ports)?
arterial transducer line. Does arterial pressure on arterial pressure.
Remove machine from service and contact the Has it reduced?
drop to zero?
Technical Services Department.
NO NO
YES YES Clamp transducer line and cap off.
YES Replace transducer line with appropriate spare. Observe arterial transducer line (red). Attach replacement line to one of the two pre-
Check the arterial transducer line (red). Has (Clamp off existing line, disconnect, attach new Are there clots in the line or at the line junction filter ports. Attach to arterial transducer and
fluid advanced all the way to the hydrophyllic line to transducer port, and connect to additive with the blood circuit? unclamp line. Arterial pressure should now be
filter? port near to arterial transducer site). Press monitoring normally.
start/reset key to recommence treatment. NO
NO YES Replace transducer line with appropriate spare.
YES Clamp arterial transducer line (red). Remove (Clamp off existing line, disconnect, attach new
Is there a clot at the base of the arterial
Replace line as detailed above. transducer line from transducer port. Does line to transducer port, and connect to additive
transducer line (red)?
arterial pressure drop to zero? port near to arterial transducer site). Press
NO start/reset key to recommence treatment.
YES Remove clots manually, following unit policy. NO
Establish if there are clots in the catheter.
Flush catheter once clots removed,
Are there clots in the access catheter? Internal failure of arterial transducer system.
recommence treatment with start/reset key.
NO Stop treatment. Return blood to patient.
YES Remove machine from operation and contact
Reconnect arterial transducer line (red). Blood Consider patient’s hydration – have they the Technical Services Department.
pump rate may be too high for patient’s become underfilled? Consult medical staff for
condition. Reduce blood pump speed. fluid assessment. Consider reducing goal for
Does this reduce the negative pressure? fluid removal.
NO
YES
Consider general circuit clotting. It may be
Has the circuit been up for a significant period,
time to change the circuit before failure due to
do they have a high platelet count?
clotting.
NO
2 3
Venous pressure too low Venous pressure too high
YES YES
Check the patient’s access catheter. Unkink catheter, press start/reset key
Consider the patient's Is it kinked at the access site? to recommence treatment.
condition. Have they become
hypovolaemic etc? Check for Take necessary action. NO
a systemic factor leading to YES Manipulate catheter. Press start/reset key until
the low return pressure. Is the venous (return) access line kinked or
flow is re-established. Consider swapping
occluded before reaching the patient?
over lines if difficult to re-establish flows.
NO NO
YES Run circuit at reduced pump speed. If pump
Check return connection to Is the blood pump rate too high? Reduce
speed needs to be less than 150 - 180 mls per
the access catheter. blood pump rate by 20%. Press start/reset
minute, consider the circuit to be clotting.
key. Observe effect on venous pressure.
Consider circuit washback and recommence
Does this solve venous pressure issue?
YES treatment.
Is the catheter connection
Tighten connection to eliminate leak. NO
loose or leaking?
YES
Clamp and cap existing transducer line.
NO
NO
Attach replacement line to one of the two
Examine venous transducer line (blue).
Is the catheter still correctly Emergency halt of treatment. Summon assistance for ports on the venous chamber and to the
Is it wet or contaminated with blood?
placed? maintenance of haemostasis and patient's condition. venous transducer port. Unclamp line. Venous
pressure monitoring should be re-established.
YES
Press start/reset key. Clamp NO NO
venous transducer line (blue). Internal transducer monitoring failure. Stop treatment. Return NO
Remove from connection blood to patient. Remove machine from operation and contact Potential internal monitoring failure. Washback
Clamp venous transducer line (blue).
port. Does venous pressure the Technical Services Department. circuit, remove machine from operation and
Disconnect from transducer port.
return to zero? contact the Technical Services Department.
Does pressure drop to zero?
YES
Replace venous transducer line YES YES YES
(blue). Attach replacement Examine venous bubble chamber for clots YES
transducer line to one of the Is the pressure now within (observe visually for dark patches externally Consider clotting as the potential cause of
Continue treatment.
outlet ports on the venous the normal limits? first, shining a light through the chamber may venous pressure increase. Consider circuit
chamber. Unclamp line. Does this make these more visible. Consider dropping the washback if venous pressure is excessive.
alter the monitored pressure? level of blood in the chamber temporarily to Reducing pump speed will reduce venous
NO NO check for clots below the surface). pressure in the short term.
NO Increase blood pump rate by YES Aim to achieve a target Are clots present?
Is the blood flow rate 20% (if patient’s condition blood flow appropriate to the NO
adequate to generate a allows). Does this produce therapy you are utilising
There might be a technical fault with
'normal' venous pressure? an increase in the venous (normally a minimum of
the machine. Please contact the Technical
pressure? 150mls/min).
Services Department.
YES NO
Consider blood clot in the
filter. Return blood to the
patient if possible.
4 5
TMP pressure too low TMP pressure too high
YES YES
Increase the replacement fluid Ensure replacement rate is kept Is there evidence that the filter
rate by 20%. Press start/reset at a suitable level for the Consider that the circuit has reached its lifespan. Wash back blood to
is clotting? (Associated rise in
key. Does this increase the TMP patient’s body mass and the the patient and recommence treatment. If circuit lifespan has been
the pre-filter pressure, visibly
pressure? size of the filter being used. low, consider the dose of anticoagulant, exchange rate, blood pump
clotted areas at the top surface
rate etc.
of the filter etc).
NO
YES NO
Is the blood pump rate high Aim for a blood pump speed
Is the effluent outlet line YES
enough? Increase the blood that is adequate for the therapy Unclamp line and press start/reset key to recommence treatment.
pump rate by 20% (if tolerated chosen, the replacement fluid clamped?
by the patient). Does this volume selected and the filter NO
increase the TMP pressure? size used. Discontinue treatment, YES YES
recommence when able. If the Check the blood pump rate, is it Reduce blood pump rate to
NO leak may be due to a too high for the filter size? within acceptable operating
YES Can the connections be NO manufacturing error, retain kit for (Check reference ranges of limits. Press start/reset key. Has Continue treatment.
Is there a leakage in the tubing maximum blood flow rates for this altered the monitored TMP
tightened to stop the fluid leak examination in a yellow plastic
system from the filter to the AV 600 and AV 1000 filters). pressure?
(and re-establish correct bag. Contact the Quality Helpline
waste bag? pressure)? to report incident and arrange
collection of kit in question. NO NO
NO YES
Observe for further failures of Press start/reset key. Check the YES Either reduce the rate of ultrafiltrate YES
Press start/reset key and
same batch in short term. removal, or increase the blood
recommence treatment. blood pump rate to ultrafiltration
pump rate to compensate. Press Continue treatment.
rate ratio (BPR/UFR). Is this too
start/reset key. Has this altered the
YES Reduce infusion rate, or change YES high (above 20%)? monitored TMP pressure?
Is there a pre-filter infusion infusion site. A change in blood Press start/reset key and NO NO
running? viscosity can artificially reduce the TMP. recommence treatment. YES
Has this altered the TMP pressure? The TMP pressure transducer cannot be replaced. Accurate TMP
Check the yellow pressure pressure monitoring will no longer be possible. It is advised that the
NO NO
transducer. Is it wet? patient’s blood be washed back and treatment be recommenced with
YES The TMP pressure transducer cannot be a new circuit.
replaced. Accurate TMP pressure
Check the yellow pressure monitoring will no longer be possible. It NO
transducer. Is it wet? is advised that the patient’s blood be YES Clamp line and remove from the YES
washed back and treatment be white pressure transducer port.
recommenced with a new circuit. Attach replacement transducer
Check the white pre-filter line to the port on the top of the Press start/reset key to
NO transducer. Is it wet? arterial chamber, and then to the recommence treatment.
YES Clamp line and remove from the white YES pressure monitoring port.
pressure transducer port. Attach Unclamp the line. Has this altered
replacement transducer line to the port the monitored TMP pressure?
Check the white pre-filter Press start/reset key and
on the top of the arterial chamber, and
transducer line. Is it wet? recommence treatment. NO NO
then to the pressure monitoring port.
Unclamp the line. Has this altered the Is the venous return line kinked YES Unkink or clear return line to re-establish unimpeded flow.
monitored TMP pressure? or occluded? Press start/reset key to recommence treatment.
NO NO NO
Consider undiagnosed issue with YES Return machine to patient use. Consider undiagnosed issue with the YES Return machine to patient use.
the fluid lines or machine. Retain used kit for examination, fluid lines or machine. Discontinue Retain used kit for examination,
Discontinue treatment. Wash blood place in yellow bag. Contact the treatment. Wash blood back to place in yellow bag. Contact Quality
back to patient. Once circuit is Quality Helpline to report incident patient. Once circuit is unloaded, Helpline to report incident and
unloaded, switch machine off and and arrange collection of kit in switch machine off and then switch arrange collection of the kit in
then switch on. Perform pre- question. Observe for further failures on. Perform pre-treatment self test. Is question. Observe for further
treatment self test. Is test passed? of same batch in short term. test passed? failures of same batch in short term.
NO NO
There might be a technical fault with the machine. There might be a technical fault with the machine.
Please contact the Technical Services Department. Please contact the Technical Services Department.
6 7
Blood leak detected Air/microbubbles detected in venous
return chamber
YES NO NO
Consider filter production Has the treatment begun – is Lower venous chamber using down arrow until chamber is clear of air.
issues. Retain filter in yellow blood in the venous chamber? Raise using up arrow. Press start/reset key to recommence treatment.
bag for collection by
Visible blood suggests a
Fresenius staff. Take filter
Check filtrate line for the significant membrane failure. YES
reference number if possible.
presence of 'frank' (visible) Were TMP pressures high NO Use up arrow to raise the level
Contact Quality Helpline to Is the level of blood above the
blood. Can you see blood in before blood leak detected, of the venous chamber to within
report incident and arrange air detector (within 2 cm of the
the line? or has it failed very early in 2cm of the top.
collection of filter in top of the venous chamber)?
treatment? Press start/reset key.
question. Observe for further
failures of same batch in YES
short term. YES Raise the level of the bubble
Press start/reset key. Has the chamber above the inflow port of
replacement fluid flow become the replacement line. Check for any
NO YES
turbulent following a bag change remaining air in the replacement
(small amounts of air entering via line. Continue treatment, observing
Microscopic blood leak. the replacement line)? for any drop in the level of blood in
Consider unit policy on the chamber.
microscopic blood leak NO
(washback or continue as Discontinue treatment. YES YES
Check connections on fluid
advised by local policy). Washback circuit blood and replacement bags. Tighten if
Clotting will occur within filter recommence treatment. Is a large amount of air entering Does the source appear to be
necessary. Check connection of
once the membrane has the bubble chamber? the replacement fluid line?
line to the venous bubble
ruptured, circuit lifespan is chamber. Tighten if required.
likely to be greatly reduced.
NO NO
YES Check outlet connection to the
filter. Tighten if necessary. Check
Does the source appear to be
the 2 pre-filter fluid additive
the filter outlet line (blue)?
ports are clamped. Check that
access line is not kinked.
NO
Are the two additive ports on NO
the top of the venous chamber Clamp port lines.
firmly clamped?
YES
If a large amount of air is entering the circuit from an unidentified source,
attempt to wash the blood back. It may not be possible to achieve safely.
Disconnect patient. Consider circuit flaw. Retain circuit for examination in
yellow bag. Contact Quality Helpline to report incident and arrange collection
of circuit in question. Observe for further failures of same batch in short term.
8 9
Pressure before filter too low Pressure before filter too high
Press start/reset key. Is there YES Is there evidence that the YES Consider that the circuit has reached its lifespan. Press
any visible leakage in the filter is clotting? (Associated start/reset key. Wash back blood to the patient and
Tighten loose connections, ensure pre-filter additive ports are
tubing system? (Consider rise in the pre-filter pressure, recommence treatment. If circuit lifespan has been low,
clamped.
from the patient access to the visibly clotted areas at the consider the dose of anticoagulant, exchange rate, blood
filter blood circuit connector). top surface of the filter etc). pump rate etc.
NO NO
NO Check the blood pump rate. YES YES
Tighten transducer into connector port. If accidently cross Reduce blood pump rate to
Is the pre-filter pressure Is it too high for the filter
threaded and a tight fit is no longer possible replace pre-filter within acceptable operating
transducer (white) connected size? (Check reference
pressure transducer with a replacement line attached to the top limits. Press start/reset key. Continue treatment.
firmly and correctly? ranges of maximum blood
of the arterial bubble chamber. Has this altered the pre-filter
flow rates for AV 600 and AV
pressure?
YES 1000 filters).
YES Clamp line and remove from YES NO NO
the white pressure YES Clamp line and remove from YES
transducer port. Attach the white pressure
replacement transducer line transducer port. Attach
Check the white pre-filter to the port on the top of the Press start/reset key to replacement transducer line
transducer line. Is it wet? arterial chamber, and then to recommence treatment. Check the white pre-filter to the port on the top of the Press start/reset key to
the pressure monitoring port. transducer line. Is it wet? arterial chamber, and then to recommence treatment.
Unclamp the line. Has this the pressure monitoring port.
altered the monitored TMP Unclamp the line. Has this
pressure? altered the monitored pre-
filter pressure?
NO NO
NO NO NO
Check blood pump segment. Stop blood pump temporarily. Open blood pump door. YES
Is it correctly positioned Manipulate pump segment until blood tubing lies correctly in its Unkink or clear return line to
within its housing? housing. Close door and restart blood pump. Is the venous return line re-establish unimpeded flow.
kinked or occluded? Press start/reset key to
recommence treatment.
YES
YES NO
Consider undiagnosed issue Return machine to patient
YES
with the fluid lines or use. Retain used kit for Consider undiagnosed issue Return machine to patient
machine. Discontinue examination, place in yellow with the fluid lines or use. Retain used kit for
treatment. Wash blood back bag. Contact Quality Helpline machine. Discontinue examination, place in yellow
to patient. Once circuit is to report incident and treatment. Wash blood back bag. Contact Quality Helpline
unloaded, switch machine off arrange collection of the kit to patient. Once circuit is to report incident and
and then switch on. Perform in question. Observe for unloaded, switch machine off arrange collection of the kit
pre-treatment self test. Is further failures of same batch and then switch on. Perform in question. Observe for
test passed? in short term. pre-treatment self test. Is further failures of same batch
test passed? in short term.
NO
NO
There might be a technical fault with the machine.
Please contact the Technical Services Department. There might be a technical fault with the machine.
Please contact the Technical Services Department.
10 11
Non-opaque/opaque fluid detector Balancing error – UF rate or substituation rate
too high
NO YES
Override alarm. Press start/reset key. Allow If alarm persists,
Override alarm,
priming with blood to continue. Consider override alarm. If
Is the venous chamber filled with blood ? increase blood
starting treatment with blood pump speed If alarm persists blood pump rate
pump rate to target
increased by 20%. after target rate is cannot be increased
Has the message as tolerated by the
achieved, examine due to the patient’s
appeared during the patient (ideally over
YES BPR/UFR, if this condition, then
transition into the next 3 minutes).
YES Stop infusion. Press start/reset key. Allow figure is above 20%, reduce the rate of
'treatment' mode? If identical alarm
circuit to re-establish flow. Restart infusion at increase BPR replacement fluid
Is there an infusion of clear fluids in progress occurs during this
a reduced rate. Rate can be incrementally further. until BPR/UFR is
via the venous chamber? time, override until
increased if blood return appears less than 20%. Does
target rate achieved.
sufficiently opaque. alarm persist?
NO NO YES
NO YES Please note: NO
Is there an unimpeded flow from the access? Unkink line, or re-establish unimpeded flow To accommodate If maximum
(If not the replacement flow may over-dilute from access. Press start/reset key to very high fluid tolerated blood
the blood within the venous chamber) recommence treatment. removal rate or pump rate has been
Has there been a
replacment fluid achieved or the
change in blood
rates, there must be blood pump is set
YES pump rate, Press start/reset key
adequate blood at the maximum for
YES replacement fluid to recommence
flow. Check the the filter, it will be
Press start/reset key. Is the blood flow lower Consider a reduction in post-dilution rate or the quantity treatment.
current BPR/UFR necessary to reduce
than anticipated (less than 150mls/min) with replacement until blood pump rate can be of ultrafiltrate that is
figure. If it is above either the
normal to high post-dilution replacement? increased. being removed from
20%, increase blood replacement fluid
the patient?
pump speed rate, or the volume
NO incrementally until it of patient fluid being
NO is 20% or below. removed as
Open the door to the detector, re-insert line so ultrafiltrate.
Is the return line correctly routed through the NO
that it lies correctly within the return clamp
opaque/non-opaque detector?
and the detector. Consider YES
Return machine to
undiagnosed issue
patient use. Retain
YES with the fluid lines or
used kit for
YES machine.
Consider undiagnosed issue with the fluid examination, place
Return machine to patient use. Retain used kit Discontinue
lines or machine. Discontinue treatment. Wash in yellow bag.
for examination, place in yellow bag. Contact treatment. Wash
blood back to patient. Once circuit is Contact Quality
Quality Helpline to report incident and arrange blood back to
unloaded, switch machine off and then switch Helpline to report
collection of the kit in question. Observe for patient. Once circuit
on. Perform pre-treatment self test. Is test incident and
further failures of same batch in short term. is unloaded, switch
passed? arrange collection of
machine off and
the kit in question.
then switch on.
NO Observe for further
Perform pre-
There might be a technical fault with the failures of same
treatment self test.
machine. Please contact the Technical batch in short term.
Is test passed?
Services Department.
NO
There might be a technical fault with the
machine. Please contact the Technical
Services Department.
12 13
Heater unable to achieve set temperature Heater over temperature
YES
Initially allow alarm to occur,
reset 2-3 times, particularly if
replacement flows are
Override alarm, allow further very low.
Are the replacement fluids
fluids to warm to room
colder than standard room
temperature before they are
temperature? NO
used.
Press start/reset key to
Does the alarm persist?
recommence treatment.
NO YES
NO NO
Please note: It may be Please note: It may be
necessary to clamp the fluid necessary to clamp the fluid
line to the venous bubble line to the venous bubble
Reposition heater bag until
Is the heater bag fully Enter bag change menu. catcher, disconnect the fluid catcher, disconnect the fluid
Is the door to the heater door closes fully. Press
housed within the heater Attempt to reseat bag to a replacement line (as asceptic replacement line (as asceptic
chamber fully closed? start/reset key to
chamber? position fully within housing. technique) and expel some technique) and expel some
recommence treatment.
of the fluid in the heater bag of the fluid in the heater bag
in order to manipulate it into in order to manipulate it into
the correct position. the correct position.
YES YES
NO NO
Please note: It may be Please note: It may be
necessary to clamp the fluid necessary to clamp the fluid
line to the venous bubble Change heater bag to the line to the venous bubble
Is the heater bag in the Is the heater bag in the
Change heater bag to the catcher, disconnect the fluid corresponding colour heater catcher, disconnect the fluid
correct heater chamber (ie correct heater chamber (ie
corresponding colour heater replacement line (as asceptic chamber. Press start/reset replacement line (as asceptic
green line in corresponding green line in corresponding
chamber. technique) and expel some key to recommence technique) and expel some
green heater etc)? green heater etc)?
of the fluid in the heater bag treatment. of the fluid in the heater bag
in order to manipulate it into in order to manipulate it into
the correct position. the correct position.
YES YES
YES
There might be a technical Check if the clamps in the replacement fluid bag are open. If
fault with the machine. Is there air in the not, open the clamps. Then enter bag change menu. Select
Please contact the Technical heater bag? deaeration of corresponding line. Carry out deaeration
Services Department. procedure. Continue treatment.
NO
14 15
Scales reverse alarm Drop Counter Rate Citrate/Calcium too low
YES NO
Manipulate until seated correctly in chamber
Is the drip chamber correctly seated in
holder. Press start/reset key to recommence
its holder?
Enter bag change menu. treatment.
Are the bags sat on the
Swap bags to the opposite
wrong scale for
scales. Press start/reset key YES
corresponding pump?
to recommence treatment. YES
Is the line from solution bag kinked or Free line / undo clamps. Press start/reset key
are the clamps on? to recommence treatment.
NO
YES
YES Kink line below the chamber outflow. Remove
chamber from holder. Move solution bag to
Is the drip chamber overfilled? below chamber and invert. Manually expel
excess fluid bag into the solution bag. Press
start/reset key to recommence treatment.
NO
NO
YES
16 17
Drop Counter Rate Citrate/Calcium too high Recommended filter size and blood flow rates
Has the machine been moved / knocked Press start/reset key. Observe for
6
immediately before the alarm? alarm recurrence.
5
NO
YES 4
Remove chamber from holder. Manually fill
QF [l/h]
Is the drip chamber too low (producing chamber slightly by squeezing. Return 3
double drops from splashing)? chamber to holder. Press start/reset key
to recommence. 2
NO
1
YES
Remove chamber from holder. Hold on side
Is there any droplet accumulation on the and rotate until all droplets are removed. 0
wall of the drip chamber? Return to holder. Press start/reset key to 0 100 200 300 400 500
recommence treatment. Blood flow QB [ml/min]
NO
18 19
Useful contact numbers
If you have followed all the advice in this guide, and you are still
experiencing problems, please refer to the table below to help you
decide how to proceed.
Technical Services
Day of week
* All calls are put through to a call centre in the UK. The call centre will bleep the
on-call person who in turn will respond to the customer within 15 minutes.
20 21
FMC UK 05/08 310 TC © Copyright 2008 Fresenius Medical Care (UK) Ltd
Fresenius Medical Care UK Limited · Nunn Brook Road · Huthwaite · Sutton in Ashfield · Notts · NG17 2HU · England ·
Phone: +44 (0) 1623 445100 · Fax: +44 (0) 1623 550807 Head office: Else-Kröner-Straße 1 · 61352 Bad Homburg v. d. H. · Germany
www.fmc-ag.com