Abstracts
sequencing and resources like mGAP have dramatically changed the ability
to identify the underlying genetic causes of previously undiagnosed dis-
eases in NHPs and advance the discovery of potentially powerful animal
models of human disease.
Joint presentation
TOUCHING THE BASICS: ANIMAL STUDY DESIGN IN TOXICOLOGICAL
AND DISCOVERY PATHOLOGY
Anna Maria Giusti 1, Josep Monne Rodríguez 2, Kerstin Hahn 3. 1 Pathology,
pRED Pharmaceutical Sciences, Roche, Zurich, Switzerland; 2 Tissue
Biomarker and Digital Pathology, Oncology, Roche, Zurich, Switzerland;
3
Pathology, pRED Pharmaceutical Sciences, Roche, Basel, Switzerland
Basic knowledge on animal study design is a requirement for toxico-
logical and discovery pathologists employed in academia or the phar-
maceutical industry. Accordingly, considerations concerning (I)
prerequisites for a study, (II) species selection and translational relevance
as well as (III) methodologies to evaluate animal experiments are
essential for optimized study setups. These questions will be discussed in
an interactive workshop focusing on examples from the toxicological and
experimental pathology.
Joint presentation
QUPATH WORKSHOP e LEARN HOW TO USE OPEN SOURCE SOFTWARE
FOR QUANTITATIVE PATHOLOGY AND BIOIMAGE ANALYSIS
Zbigniew Mikulski 1, Robert Klopfleisch 2, Marc Aubreville 3. 1 Microscopy
and Histology Core Facility, La Jolla Institute, San Diego, California, USA;
2
Prof. Dr. Dipl. ACVP, Specialist in Veterinary Pathology, Institute of
Veterinary Pathology, Berlin, Germany; 3 Professor for Image Understanding
and Medical Application of Artificial Intelligence, Nuremberg, Germany
This workshop aims to give participants a better understanding of how to
use QuPath for image analysis. We will cover the most common analysis
tasks, and teach how to use convenient tools for manual counting and
measurements of the length and area of different structures. We will use
QuPath’s commands for automated cell counts in H&E and immunohis-
tochemistry (IHC) slides. With the help of machine learning, we will
42
Journal of Comparative Pathology 203 (2023) 41e42
teach the software how to perform object and pixel classification, which
is very useful in complex and difficult samples. We will also perform
measurements of IHC-stained areas. All of these analyses can be easily
adapted for immunofluorescence and multiplexed slides. We will present
an outlook for the future, share examples of implementation of deep-
learning workflows, and show how QuPath can help to improve the
reproducibility of image analysis. Attendees will go home with knowl-
edge and workflows that they can adapt to analyse their own tissues and
stains.
Invited lecture
WOMEN IN ACADEMIA AND RESEARCH: STILL A LONG WAY TOWARD
GENDER EQUALITY AND INCLUSION IN VETERINARY SCIENCE AND
VETERINARY PATHOLOGY?
Chiara Palmieri. Professor in Veterinary Pathology, University of Queensland,
School of Veterinary Science, Gatton Campus, Queensland, Australia
The experience of people working in academia and research who identify
as women is very different to that of men. Discrepancies between men and
women have been quite obvious for decades and the COVID-19 pandemic
has just “helped” to enlarge this gap. One key finding presented in the
Global Gender Gap Report of the World Economic Forum 2020 is that
gender parity will not be achieved in the next 100 years. This should not be
a setback (we are not going to be here in 100 years’ time, so why bother?),
but an incentive to re-group, plan and dismantle the pipeline. However,
identifying the root causes and how to solve them all boil down to one
thing: getting the right data, getting enough data and filling the gender
data gap.
This presentation will present data on gender representation at different
academic levels in the veterinary schools, gender and research produc-
tivity in the field of veterinary pathology during the pandemic, gender
inequality on editorial boards of veterinary science journals, gender rep-
resentation at scientific conferences and the influences of gender in aca-
demic veterinary pathology, asking you to look at the evidence and engage
with it. Engagement means scrutinizing your own environment, pulling
apart strong barriers that include gender stereotypes and assumptions of
what it means to be a good leader, academic or scientist and creating a
support network committed to reducing (or better removing) gender bias
in the workplace.