V.

DRUG STUDY
DRUG NAME ACTUAL MECHANISM OF INDICATION ADVERSE NURSING RESPONSIBILITIES
DOSAGE, ACTION REACTION
ROUTE,
FREQUENCY
GENERIC NAME: 25 mg once daily Activates several To treat major depressive  Anxiety BEFORE:
Agomelatine at bedtime physiological signal episodes
transduction  Dizziness  Ask about the history of allergies, particularly to
BRAND NAME: pathways via the  Fatigue this medication
Valdoxan release of melatonin  Nausea  Apply the 5 rights before giving the medication
from the pineal  Check the expiration date in the box of the drug
 Abdominal
CLASSIFICATION: gland  Establish rapport about the possible adverse effect,
Agonist at Melatonin pain and the use of the drug
receptors (MT1 and  Hallucinations
MT2) and as an  Agitation DURING:
antagonist at
serotonin (5-HT)  Blurred vision
 Make sure the patient take this drug after meal
(2C) receptors  Constipation to avoid stomach upset
CONTRAINDICATION  Make sure to give the medication in tablet
form, and instruct the patient not to chew or
Agomelatine is suck the tablet
contraindicated in
patients with hepatic AFTER:
impairment
 Document the drug, dose, route, time given and
time discontinued if applicable and document any
ADR
 Remember to give the next medication on time.
 DRUG NAME ACTUAL MECHANISM OF INDICATION SIDE EFFECT NURSING RESPONSIBILITIES
DOSAGE, ACTION REACTION
ROUTE,
FREQUENCY
GENERIC NAME: 3-6 mg PO within Increasing the Treatment of depression  Blurred vision BEFORE:
Doxepin 30 minutes before concentration of the and/or anxiety
bedtime neurotransmitter's  Decreased urine  Ask about the history of allergies, particularly
BRAND NAME: serotonin (5-HT) output to this medication
Prudoxin and norepinephrine  Constipation  Apply the 5 rights before giving the
(NE) in the brain medication
 Dizziness
CLASSIFICATION:  Check the expiration date in the box of the
Tricyclic  Drowsiness drug
Antidepressants  Xerostomia  Establish rapport about the possible adverse
(TCA)  Nausea effect, and the use of the drug
 Heartburn
DURING:
 Rash
 Make sure the patient take this drug after
CONTRAINDICATION
meal to avoid stomach upset
 Make sure to give the medication in tablet
Doxepin is
form, and instruct the patient not to chew
contraindicated in
or suck the tablet
individuals who have
shown hypersensitivity to
AFTER:
TCAs (tricyclic
antidepressants), doxepin,
 Document the drug, dose, route, time given
or any of the inactive
and time discontinued if applicable and
ingredients
document any ADR
 Remember to give the next medication on
time.
 DRUG NAME ACTUAL MECHANISM OF INDICATION SIDE EFFECT NURSING RESPONSIBILITIES
DOSAGE, ACTION REACTION
ROUTE,
FREQUENCY
GENERIC NAME: 300 mg daily in 2 Moclobemide To treat social anxiety  Psychomotor BEFORE:
Moclobemide divided doses involves the disorder
selective, reversible agitation  Ask about the history of allergies, particularly to
BRAND NAME: inhibition of MAO-  Trouble this medication
Manerix A sleeping  Apply the 5 rights before giving the medication
 Aggressive  Check the expiration date in the box of the drug
CLASSIFICATION:  Establish rapport about the possible adverse effect,
Monoamine Oxidase behavior and the use of the drug
(MAO) inhibitors  Anxiety
 Headache DURING:
CONTRAINDICATION
 Abdominal
 Make sure the patient take this drug after meal
Avoided by patients on an pain to avoid stomach upset
MAOI include  Diarrhea  Make sure to give the medication in tablet
phenylpiperidine opioids, form, and instruct the patient not to chew or
meperidine (pethidine,  Dizziness
suck the tablet
Demerol), tramadol,  Xerostomia
methadone, and AFTER:
dextromethorphan
 Document the drug, dose, route, time given and
time discontinued if applicable and document any
ADR
 Remember to give the next medication on time.