Name: Silbert, Sara May L.

Date: December 11, 2023

Section: CN 252 NCM 106 Pharmacology

DRUG STUDY
(Lower respiratory system drug)
ADVERSE
DRUG MECHANISM INDICATIONS CONTRAINDICATIONS REACTIONS/ NURSING
OF ACTION EFFECTS CONSIDERATIONS
Generic name: Arformoterol is in
a class of Arformoterol is Before using arformoterol, Check with your This medicine may
Arformoterol medications used for the long- tell your doctor or doctor right affect blood sugar
called long- term pharmacist of all the drugs away if you have levels. If you are
Brand name: acting beta maintenance you take and if you have more than one of diabetic and notice a
Brovana agonists treatment of air any of the following the following change in the results of
(LABAs). It flow blockage in conditions: certain heart symptoms: your blood or urine
works by patients with problems (heart failure, decreased urine, sugar tests, check with
Classification: relaxing and chronic slow heartbeat, QT dry mouth, your doctor. This
Arformoterol is in a opening air obstructive prolongation in the EKG), increased thirst, medicine may cause
class of passages in the pulmonary family history of certain loss of appetite, serious allergic
medications lungs, making it disease (COPD), heart problems (QT mood changes, reactions, including
called long- easier to including chronic prolongation in the EKG, muscle pain or anaphylaxis and
acting beta breathe. bronchitis and sudden cardiac death). cramps, nausea angioedema, which can
agonists (LABAs). It emphysema. or vomiting, be life-threatening and
works by relaxing COPD is a long- numbness or require immediate
and opening air term lung tingling in the medical attention.
passages in the disease that hands, feet, or
lungs, making it causes lips, seizures,
easier to breathe. bronchospasm uneven
(wheezing or heartbeat, or
Dosage: difficulty with unusual
For oral inhalation breathing). tiredness or
dosage form weakness.
(solution):
-For maintenance
treatment of COPD:
  Adults—15
micrograms
(mcg) 2
times a day
(morning
and
evening) by
nebulization.
The total
dose should
not be more
than 30 mcg
per day.
 Children—
Use and
dose must
be
determined
by your
doctor.
Route:
Arformoterol
belongs to the
family of medicines
known as
bronchodilators.
Bronchodilators are
medicines that are
breathed in through
the mouth to open
up the bronchial
tubes (air
passages) in the
lungs.
Name: Silbert, Sara May L. Date: December 11, 2023
Section: CN 252 NCM 106 Pharmacology

DRUG STUDY
(upper respiratory system drug)
ADVERSE
DRUG MECHANISM INDICATIONS CONTRAINDICATIONS REACTIONS/ NURSING
OF ACTION EFFECTS CONSIDERATIONS
Generic name: Azithromycin is a Azithromycin is These common Instruct patient not to
Azithromycin Azithromycin broad-spectrum contraindicated in patients side effects of take azithromycin with
mechanism of macrolide with a history of severe azithromycin food or antacids. May
action including antibiotic with a hypersensitivity (e.g., happen in more cause drowsiness and
Brand name: the inhibition of long half-life and anaphylaxis or SJS) to than 1 in 100 dizziness. Caution
Azasite, Zithromax, bacterial protein a high degree of azithromycin or another people. There are patient to avoid driving
Zmax synthesis, tissue macrolide antimicrobial. In things you can do or other activities
inhibition of penetration 3. It addition, clinicians should to help cope with requiring alertness until
Classification: proinflammatory was initially be cautious regarding the them: response to medication
Azithromycin cytokine approved by the concomitant use of  Feeling is known. Advise
belongs to the class production, FDA in 1991 4. It azithromycin and other sick patient to use
of drugs known as inhibition of is primarily used medications that prolong (nausea) sunscreen and
macrolide neutrophil for the treatment the QTc interval (e.g.,  Diarrhoea protective clothing to
antibiotics. It works infestation, and of respiratory, antipsychotics).  Being sick prevent
by killing bacteria or macrophage enteric and Azithromycin is (vomiting) photosensitivity
preventing their polarization genitourinary contraindicated for patients  Losing reactions.
growth. However, alteration, gives infections and taking the first-generation your
this medicine will it the ability to may be used antipsychotic pimozide. appetit
not work for colds, act against a instead of other Macrolide antimicrobials  Headaches
flu, or other virus wide range of macrolides for inhibit CYP3A4, the same Feeling
infections. microorganisms. some sexually cytochrome that dizzy or
Dosage: transmitted and metabolizes pimozide; tired
- Injection, enteric concomitant use of  Changes
lyophilized infections. It is azithromycin with pimozide to your
powder for structurally can cause dangerous sense of
reconstitution plasma concentrations of taste
500mg/vial
 - tablet related to pimozide, leading to QTc
250mg erythromycin 2. prolongation and,
500mg potentially, lethal
- oral arrhythmias. While
suspension azithromycin is a poor
100mg/5mL inhibitor of CYP3A4 relative
200mg/5mL to other macrolides,
Route: avoidance of this
Azithromycin is interaction is still
available for both advisable.[39][40]
oral and parenteral Additionally, azithromycin is
(intravenous) an inhibitor of p-
administration. The glycoprotein/ABCB1, a cell
extended-release membrane glycoprotein
formulation of transporter. Drugs that are
azithromycin has substrates of P-
been discontinued. glycoprotein, particularly
The usual dose is those that are also
250 mg or 500 mg, substrates of CYP3A4, may
given once daily for represent a relative
3 to 5 days, and in contraindication to
severe infections, a azithromycin. Examples
higher dose is include colchicine and
used. small-molecule calcitonin
gene-related peptide
(CGRP) antagonists.