NAME: Presbitero, Nielmae SUBJECT: NCM112 Care of Clients with Problems in Oxygenation, Fluid & Electrolytes, and Infectious,

luid & Electrolytes, and Infectious, Inflammatory & Immunologic Response, Cellular Aberrations (Acute & Chronic)
COURSE: BSN 3B DATE: September 24, 2022

Pharmacological Nursing Study (Drug Study)

Generic/Brand Dose Strength & Indication/ Mechanism of Adverse/Side Effects & Nursing Responsibilities Rationale Client Teaching Evaluation
Name & Drug Formulation Drug Action Drug Interaction
Classification

GENERIC NAME: DOSAGE: INDICATION: ADVERSE EFFECTS:

Diphenhydramine Adult: 25-50 mg PO Symptomatic relief of  Drowsiness  Administer drug on  To increase the  Antihistamines are  Monitor patient
q4-6 h or 10-50 mg perennial and seasonal  Sedation an empty stomach 1 absorption of the commonly used to response to the
BRAND NAME: IM or IV rhinitis,  Dizziness hour before or 2 hours drug treat the signs and drug (relief of
Benadryl
Pediatric: 12.5-25 mg vasomotor rhinitis, allergic  Epigastric Distress after meals; symptoms of the symptoms
PO t.i.d to q.i.d or 5 conjunctivitis, urticaria, and  Thickening of  Note that the patient  To find the one various allergic of
mg/kg/d IM or IV angioedema; Bronchial may have poor that is most reactions. Because allergic rhinitis)
DRUG
CLASSIFICATION:
Geriatric: Use caution also used for treating motion Secretions response to one of effective these drugs work  Monitor for
sickness and parkinsonism  Urinary Retention these agents but an throughout the adverse effects
and as a  Rash effective response to body, many systemic (skin dryness,
Antihistamines nighttime sleep aid and to  Bradycardia another; the prescriber effects can occur with GI upset,
suppress cough may need to try their use sedation and
several different  Take this drug only as drowsiness,
agents prescribed. Do not urinary
 Because of the drying  To relieve some increase the dose if retention,
FORMULATION: MECHANISM OF ACTION: DRUG INTERACTION: nature of of this symptoms are not thickened
antihistamines, Discomfort relieved. Instead, secretions,
Competitively blocks the
Each 5 mL of Drug–drug interactions patients often consult your glaucoma)
effects of histamine at
Benadryl Original histamine- vary among the experience dry mouth, healthcare provider  Monitor the
contains 12.5 mg of 1 receptor sites; has atropine- antihistamines; for which may lead to  Avoid the use of effectiveness of
diphenhydramine like antipruritic and sedative example, nausea and anorexia; alcoholic beverages comfort and
hydrochloride and 125 effects anticholinergic effects suggest sugarless while you are taking safety measures
mg of ammonium may be prolonged if candies or lozenges this drug. Serious and
chloride as the active diphenhydramine is taken  Provide safety  To prevent drowsiness or compliance
ingredients. This with an measures as patient injury sedation can occur if with the
medicine contains MAO inhibitor, and the appropriate if CNS these are combined regimen
135.2mg/40mL interaction of fexofenadine effects occur  Avoid the use of any
(maximum daily dose) with ketoconazole or  Increase humidity and  To decrease the OTC medication
of sodium erythromycin may raise push fluids problem of without first checking
fexofenadine thickened with
concentrations to toxic secretions and your healthcare
levels. For more dry nasal mucosa provider. Several of
information, consult a these medications
nursing drug handbook or contain drugs
package insert for  To decrease that can interfere with
individual  Have patient void urinary retention the effectiveness of
details before each dose if this is a this drug, or they can
problem contain similar drugs
 To prevent skin and you could
 Provide skin care as breakdown experience toxic
needed if skin dryness effects
and lesions become a  Tell any doctor, nurse,
problem  Which are found or other healthcare
 Caution the patient to in many OTC provider involved in
avoid excessive dose preparations and your care that you are
and to check OTC could cause taking this drug
drugs for the presence toxicity  Take this drug only as
of antihistamines  Because prescribed.
serious sedation
 Caution the patient to can occur
avoid alcohol while  To help the
taking these drugs patient cope with
the
 Offer support and disease and the
encouragement drug regimen
GENERIC NAME: DOSAGE: INDICATION: ADVERSE EFFECTS:

Atropine Sulfate  For pre-op:  Contraindicated in  CNS: Drowsiness,  Check patient’s  Increases  Atropine may cause  For bradycardia:
IM, IV, patients with Blurred Vision medication hx for anticholinergic drowsiness. Don’t Increased HR.
BRAND NAME: Subcutaneous glaucoma, pyloric  CV: Tachycardia, drug-drug effects when operate heavy  Others:
 For S/E of stenosis (children), Palpitations, interactions, PMHx, used with other machinery or drive until Decreased
AtroPen they know how the GI/respiratory
cholinergic: IV Obstructions in the GI Arrhythmias and allergies. anticholinergic
medication affects them. secretions, N/V,
DRUG  For muscarinic tract, tachycardia,  GI: Impaired GI  Assess and monitor medications
CLASSIFICATION:  For dry mouth: mouth diarrhea
poisoning: IM, CHF, hx of heart Motility, Dry patient’s vital signs (antihistamines, rinsing, oral hygiene, (muscarinic
Anticholinergics IV disease and HTN Mouth, and ECG. Report TCAs, quinidine, chew sugarless gum. effects)
 For  Use cautiously in the Constipation chest pain or any dysopyramide)  Take caution in hot
Bradycardia: elderly, hx of chronic  GU: Urinary changes to HR/BP to  May decrease GI environments. Atropine
- IV (adults) - 0.5- lung disease, paralytic Retention, provider immediately. tract mobility = impairs heat regulation
1mg ever 3-5mins; ileus, prostatic Impotency  Monitor I&Os alters absorption and could cause a heat
do not exceed total hypertrophy. Safety is  Respiratory: (urinary retention) of other PO meds stroke.
of 2mg unknown for OB Tachypnea,  Assess patient’s BM  Decreased
- IV/Endotracheal patients but IV Pulmonary Edema and BS (constipation) absorption when
(children) administration may  Others: Flushing, Increase fluids. used with
 Bronchospasm: cause fetal Decreased  Antidote for OD: antacids
Inhalation tachycardia Sweating Physostigmine  May cause
- Adults 0.025mg- altered response
0.05mg/kg/dose q4h when used with
PRN beta-blockers
- Max is 2.5mg/dose
FORMULATION: MECHANISM OF ACTION: DRUG INTERACTION:

Each mL contains Blocks the action of  Eluxadoline

Atropine Sulfate 0.4 acetylcholine on the CNS,  Glucagon
mg; Sodium Chloride smooth muscles,  Glucagon
9 mg; Benzyl Alcohol Cardiac muscles, and Intranasal
9 mg; Water for secretory glands. It has  Glycopyrronium
Injection qs; pH may anticholinergic effects. It can Tosylate Topical
be adjusted with increase HR, decrease  Macimorelin
Sulfuric Acid if GI/respiratory secretions,  Pramlintide
necessary. pH 3.0-6.5 and reverse muscarinic  Revefenacin
effects from CV, respiratory,  Secretin
and GI systems (bradycardia,  Umeclidinium
hypotension, rhinorrhea,
Bromide/Vilanterol
N/V, diarrhea)
Inhaled