Table of Contents

Anatomy & Physiology 1 Tubular Secretion of Para-aminohippuric Acid

(PAH) 36
Acid-Base Physiology 6 Urea Recycling 38
Acid-Base Map & Compensatory Mechanisms Weak acids & Bases – Non Ionic Diffusion 38
6
Buffering & Henderson-Hesselbalch Equation 7 Water Regulation 39
Physiologic pH & Buffers 8 Osmoregulation 39
Plasma Anion Gap 9 Kidney Countercurrent multiplication 40
The role of the kidney in Acid-Base Balance 9 Antidiuretic Hormone 43
Metabolic Acidosis 10 Free Water Clearance 45
Metabolic Alkalosis 11
Respiratory Acidosis 12
Respiratory Alkalosis 13

Fluids in the Body 14

Body Fluid Compartments 14
Water Shifts between Body fluid Compartments
16
Renal Clearance 19

Renal Blood Flow Regulation 21

Renal Blood Flow Regulation 21
Measuring Renal Plasma Flow & Renal Blood
Flow 23

Renal Electrolyte Regulation 24

Glomelular Filtration 24
Proximal Convoluted Tubule 26
Loop of Henle 27
Distal Convoluted Tubule 28
TF/Px Ratio & TF/P Inulin 29
Calcium Homeostasis 30
Magnesium Homeostasis 30
Phosphate Homeostasis 31
Potassium Homeostasis 31
Sodium Homeostasis 32

Renal Reabsorption & Secretion 34

Tubular Reabsorption & Secretion 34
Tubular Reabsorption of Glucose 34