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Received: 27 May 2020 Revised: 28 November 2020 Accepted: 26 March 2021

DOI: 10.1002/cpp.2591

COMPREHENSIVE REVIEW

Differential diagnosis of borderline personality disorder and


bipolar disorder: Self-concept, identity and self-esteem

Livia Wright1 | Lisa Lari1 | Stefania Iazzetta1 | Marco Saettoni1,2 |


Andrea Gragnani1,2,3

1
Scuola di Psicoterapia Cognitiva SRL,
Grosseto, Italy Abstract
2
Unità Funzionale Salute Mentale Adulti, ASL Symptoms of borderline personality disorder (BPD) and bipolar disorder (BD) often
Toscana Nord-Ovest Valle del Serchio, Pisa,
overlap. In some cases, it is difficult to conduct a differential diagnosis based only on
Italy
3
Scuola di Psicoterapia Cognitiva SRL, Rome, current diagnostic criteria Therefore, it is important to find clinical factors with high
Italy discriminatory specificity that, used together with structured or semi-structured

Correspondence interviews, could help improve diagnostic practice.


Livia Wright, Scuola di Psicoterapia Cognitiva We propose that a clinical analysis of identity, self-concept and self-esteem may help
(SPC), Via Giovanni Lanza 26, 58100 Grosseto,
Italy. distinguish the two disorders, when they are not co-morbid. Our review of the stud-
Email: liviawright@gmail.com; ies that analyse these constructs in BD and BPD, separately, points in the direction
studiogrosseto@scuola-spc.it
of qualitative differences between the two disorders. In BPD, there is a well-
documented identity diffusion, and the self-concept appears predominantly negative;
shifts in self-concept and self-esteem are often tied to interpersonal triggers. In BD,
patients struggle with their identity, but narrative identity might be less compromised
compared with BPD; the shifts in self-concept and self-esteem appear more linked to
internal (i.e. mood and motivational) factors. We end the paper by discussing the
implications for clinicians and ideas for future comparative research.

KEYWORDS
bipolar disorder, borderline personality disorder, differential diagnosis, identity, self-concept,
self-esteem

1 | I N T RO DU CT I O N There are epidemiological and aetiological differences between


BPD and BD (Paris & Black, 2015) that support this classification.
Current international classifications (Diagnostic and Statistical Manual Environmental factors, together with a temperamental predisposition,
for Mental Disorders Fifth Edition [DSM-5], American Psychiatric appear to be a core etiological feature of BPD (Linehan, 1993),
Association, 2013; International Statistical Classification of Diseases whereas BD has a strong familial pattern (Rowland &
and Related Health Problems 11th Revision [ICD-11], World Health Marwaha, 2018). The illness course also seems to differ: Many individ-
Organization, 2019) consider bipolar disorder (BD) and borderline per- uals with BPD no longer meet criteria in middle age (Zanarini
sonality disorder (BPD) two different disorders. In the DSM-5, BPD is et al., 2012), whereas BD does not seem to remit with age. On the
one of the Cluster B personality disorders, together with antisocial contrary, depressive symptoms appear to worsen over time (Coryell
personality disorder, histrionic personality disorder (HPD) and narcis- et al., 2009). In addition, antidepressants, anticonvulsant mood stabi-
sistic personality disorder (NPD). Bipolar disorders are a separate diag- lizers and atypical antipsychotics appear beneficial for BD, although
nostic entity that includes bipolar disorder I (BD I), bipolar disorder II patients with BPD have lower rates of response to pharmacological
(BD II) and cyclothymic disorder, among others. treatment (Ripoll et al., 2011). These differences are clear in the

Clin Psychol Psychother. 2021;1–36. wileyonlinelibrary.com/journal/cpp © 2021 John Wiley & Sons, Ltd. 1
2 WRIGHT ET AL.

scientific research, but their utility is limited in the psychiatric practice,


where at a first glance the symptoms of the two disorders seem to
Key Practitioner Message
overlap (Borda, 2016).
• Differences between borderline personality disorder and
The picture is further complicated by co-morbidity. Despite the
bipolar disorder are clear in the scientific research, but
differences described, co-morbidity of the two disorders is very com-
their utility is limited in the psychiatric practice, where at
mon (for a review, please see Bezerra-Filho et al., 2015 and
a first glance the symptoms of the two disorders seem to
McDermid et al., 2015), and the negative impact of BPD on BD is
overlap.
greater than vice versa (Frías et al., 2016).
• For diagnostic and treatment purposes, clinicians should
Although we acknowledge that co-morbidity is very common and
ideally conduct a thorough assessment to obtain a gen-
clinically relevant, our aim is to aid differential diagnosis; therefore, in
eral picture of each patient's intrapsychic and interper-
this review article, we will consider patients with one of the two diag-
sonal functioning, including their self-concept as it has a
noses. In this case, it is easier to differentiate BD I from BPD than BD
pivotal role in the clinical picture.
II from BPD because of the characteristic manic symptoms and com-
• In BPD, there is a well-documented identity diffusion,
mon psychotic symptoms in BD I (Goodwin et al., 2007). Hypomania,
and the self-concept appears predominantly negative;
however, has a milder presentation, cannot include psychotic symp-
shifts in self-concept and self-esteem are often tied to
toms (DSM-5, Criteria E ‘Hypomanic episode’) and therefore can
interpersonal triggers. In BD, patients struggle with their
often be confused with the emotional dysregulation in BPD, and vice
identity, but narrative identity might be less compromised
versa (Kernberg & Yeomans, 2013).
compared with BPD; the shifts in self-concept and self-
Ruggero et al. (2010) found that in a sample of 82 patients with a
esteem appear more linked to internal (i.e. mood and
previous misdiagnosis of bipolar disorder, who did not have it
motivational) factors.
according to the Structured Clinical Interview for DSM-IV Axis I
• There is some evidence that targeting these constructs in
(SCID-I), patients with BPD had a significantly greater risk of a mis-
therapy may be beneficial to the patient.
diagnosis, regardless of how they met the borderline criteria. A correct
diagnosis is important because pharmacological and psychotherapeu-
tic treatment of BD and BPD differs (Bayes et al., 2016; Paris &
Black, 2015) and for the implications of the diagnosis for the patient's
quality of life (QoL), stigma, relationships etc. (Bilderbeck et al., 2014). these constructs might have high discriminatory specificity, unlike
Diagnostic confusion also hinders research and knowledge develop- other clinical factors such as altered mood states and impulsivity that
ment of the two conditions. are considered transdiagnostic (Bayes & Parker, 2019; Ghaemi
Even though differential diagnosis of BD and BPD is challenging et al., 2014). We wish to analyse them in greater depth and connect
and has many implications for clinical care and research, few studies them to clinical findings to assist the design of studies that aim to
directly compare the two disorders (Paris & Black, 2015). Saunders advance the clinical distinction. In support of our hypothesis, as we
et al. (2015) conducted an original and methodologically sound study were writing this article, Bayes and Parker (2019) published a study
of clinical practice. They analysed clinician interviews and adminis- on a sample of 53 participants with BPD and 83 participants with
tered questionnaires to a sample of UK psychiatrists to investigate BD. Results of a 113-item self-report questionnaire, comprising cogni-
how they approached the differential diagnosis of the two disorders tive and behavioural constructs weighted to a borderline personality
and to test their knowledge of DSM-IV-TR criteria. The study showed style, showed that identity disturbance is intrinsic and specific to BPD
that most of the psychiatrists in the sample demonstrated a compre- and thus might help the differentiation with BD.
hensive understanding of the diagnostic criteria, but they were very We offer a brief description of identity, self-concept and self-
sceptical towards them and often relied on their clinical judgement. esteem, as found in the literature. Then, we review studies that ana-
Following this impressionistic approach, symptoms of mania and BPD lyse these constructs in BD and BPD, separately. Lastly, we discuss
were rarely sufficiently explored to establish the absence or presence the results of the review. We adhere to a cognitivist theory that
of each diagnosis. This approach can lead to diagnostic errors. believes that cognitions and goals, together with genetic and environ-
But if, indeed, current diagnostic criteria alone are not sufficient mental factors, can explain the origin and maintenance of psychologi-
for a differential diagnosis in some cases, it is important to find clinical cal suffering (Castelfranchi, 2012; Mancini, 2016). Therefore, we will
factors with high discriminatory specificity that, used together with attempt to organize the results following this cognitivist perspective.
structured or semi-structured interviews, could help improve diagnos-
tic practice.
In this regard, we propose that a clinical analysis of identity, self- 2 | METHODS
concept and self-esteem may help distinguish the two disorders. The
comparison of these constructs in BPD and BD has already been con- Preliminarily, we conducted a computerized search in the PubMed
ducted in the context of broader reviews (Bassett, 2012; Bayes database on 1/4/2019: ‘bipolar disorder AND borderline personality
et al., 2014) and one specific article (Borda, 2016). These suggest that disorder AND differential diagnosis’ that yielded 80 results. Of these,
WRIGHT ET AL. 3

32 studied the differential diagnosis of the two disorders. Based on research articles that in any way concerned identity, self-concept and
those articles, we hypothesized that the construct ‘identity’ could be self-esteem in BPD or BD patients. To obtain as comprehensive a
a suitable candidate to aid differential diagnosis. Therefore, we con- review as possible, we included articles that did not appear in the
ducted four separate computerized searches in the PubMed database: searches but were cited by the original articles, as others previously
(1) ‘bipolar disorder AND identity’, (2) ‘bipolar disorder AND self- did (e.g. Bech et al., 2015). We did not include studies on student
concept OR self-esteem’, (3) ‘borderline personality disorder AND populations, studies on samples with BPD or BD features or case
identity’ and (4) ‘borderline personality disorder AND self-concept reports. We did not include other constructs, such as dissociation,
OR self-esteem’. The search was restricted to articles in English publi- splitting, early maladaptive schemas, metacognitive processes, insight
shed between 1/1/2000 and 1/1/2020. Using the Rayyan review and autobiographical memory (in general, not identity related), trauma,
software (Ouzzani et al., 2016), we collapsed the results of the first even though they are intimately related to the analysed constructs, as
two and last two searches to identify unique results. We read all the the studies resulting from the search were limited compared with the
titles and abstracts and established if they were relevant. We included whole production on the subject. The process can be seen in Figure 1.

FIGURE 1 Flow chart of the search strategy


4 WRIGHT ET AL.

3 | A GL OS SA R Y F O R T H E R E A D ER according to diagnostic approaches (American Psychiatric


Association, 2013; World Health Organization, 2019) and several the-
Many different definitions of self, self-concept and identity exist. These ories (Bender & Skodol, 2007; Jørgensen, 2010; Kernberg, 1967;
concepts are often used interchangeably (Kerr et al., 2015). This is also Linehan, 1993; Luyten et al., 2019; Meares et al., 2011). The DSM-5
true in the reviewed studies, and part of the confusion concerning describes BPD as ‘a pervasive pattern of instability of interpersonal
these concepts in the two disorders can be traced back to this misuse. relationships, self-image and affect, and marked impulsivity, beginning
This description is by no means an exhaustive analysis of these by early adulthood and present in a variety of contexts, as indicated
complex constructs (for a more detailed analysis, see Kerr et al., 2015; by five (or more) of the following [9 criteria]’, Criterion 3 being ‘Iden-
Leary & Tangney, 2012). It serves two purposes: (1) to establish a tity disturbance: markedly and persistently unstable self-image or
common starting point with the reader and (2) to inform the reader sense of self’. The shifts in self-image refer to sudden and dramatic
of the importance of a correct definition when designing future shifts in goals, aspirations and values. In the diagnostic features, the
studies. DSM-5 goes on: ‘Although they usually have a self-image that is
Self-concept: It is a product of the reflexive activity of the self. It based on being bad or evil, individuals with this disorder may at times
involves mental concepts of ‘who one is, was and will become’ have feelings that they do not exist at all’. The authors of the DSM-5
(Oyserman et al., 2012). Gecas (1982) conceptualizes it as ‘an organi- do not offer a clear and precise definition of self and identity.
zation (structure) of various identities and attributes, and their evalua- Turning to the literature, both the knowledge component and the
tions, developed out of the individual's reflexive, social, and symbolic evaluative component of the self-concept appear to be compromised
activities. As such, the self-concept is an experiential, mostly cognitive in this disorder. Individuals with BPD seem to have great difficulties in
phenomenon accessible to scientific inquiry’ (p. 4). the process of creating the feeling of self-continuity and self-
Identity: The knowledge component of the self (‘Who am I?’; coherence, especially in the presence of interpersonal stressors
‘Who was I?’; ‘Who am I going to become?’; ‘Who am I in every con- (Luyten et al., 2019; Semerari et al., 2005). They have what can be
text?’). Identities are the traits and characteristics, social relations, called an ‘identity diffusion’, that is, ‘a fragmentation rather than inte-
roles and social group memberships that define who one is. Together, gration of the representations of the self and others’ (Yeomans
identities make up a part of one's self-concept. et al., 2002, p. 8). This is confirmed by several empirical studies
Narrative identity: ‘the capacity of the individual to integrate (e.g. Jørgensen, 2009). Identity disturbance seems to be present in
contradictory aspects and tendencies into a coherent, overarching patients with and without a history of abuse (Wilkinson-Ryan &
sense and view of his or her self’ (Fuchs, 2007, p. 380). Thus, feelings Westen, 2000), but the degree may vary. There is also evidence that
of self-coherence and self-continuity are an illusion, a product of this higher levels of identity diffusion in BPD are associated with greater
capacity, that can be disrupted, as we will see further on. symptom severity (Sollberger et al., 2012) and worse functional prog-
Self-esteem: An evaluative component of the self-concept. It nosis (Esguevillas et al., 2018).
answers the question: ‘How do I feel about my various identities?’ Patients with BPD report a trait-like predisposition towards nega-
(Campbell & Lavallee, 1993). Self-esteem can be broken down in tive affect (Dukalski et al., 2019) and high levels of current negative
implicit self-esteem (ISE) and explicit self-esteem (ESE). Measures of affect (Walter et al., 2009). They have trouble describing themselves
ESE explicitly ask individuals about their assessment of themselves. (Dammann et al., 2011) and their self-concept is mostly negative
Measures of ISE assess ‘the degree to which the self is cognitively (Baumann et al., 2020; Beeney et al., 2016; van den Heuvel
associated with positive versus negative thoughts’ (Spalding & et al., 2012; Vater et al., 2015) and unstable (Beeney et al., 2016;
Hardin, 1999). Kanske et al., 2016) as is the content of their narrative identity
Both components of the self, self-knowledge or identity and self- (Jørgensen et al., 2012). At a neural level, individuals with BPD may
esteem, can be treated as traits or states (for a discussion, see Winter utilize less organized and more complex strategies for representing
et al., 2017). self and others (Beeney et al., 2016).
Self-stigma: Intimately related to self-esteem, it consists of agree- Nonetheless, they generally aspire to a future positive self-con-
ing with and applying to oneself the public negative stereotypes and cept, which is described as desired, probable and important (Janis
prejudices associated with the diagnosis (Rüsch et al., 2006). et al., 2006), but are generally unable to pursue it. Negative self-views
With these definitions in mind, we can now turn to the descrip- might be maintained by a bias for negative self-relevant information
tion of self-concept, identity and self-esteem in BPD and BD. (Auerbach et al., 2016; Korn et al., 2016; Winter, Herbert, et al., 2015;
Winter, Koplin, & Lis, 2015) and an excessive focus on negative social
feedback (van Schie et al., 2019). The negative self-concept is greater
4 | RESULTS in explicit measures (Sarkheil et al., 2019; Winter et al., 2018) com-
pared with implicit measures (Donges et al., 2016), meaning that it is
4.1 | Identity, self-concept and self-esteem in BPD enhanced by cognitive processing.
Further insight concerning the content of the identity disturbance
The nature of BPD is controversial (Shedler et al., 2010), but impair- and its' longitudinal course over 20 years is given to us by Gad
ments of self and identity are a central factor of the disorder et al. (2019). The authors measured four maladaptive inner states that
WRIGHT ET AL. 5

are aspects of the self-concept, namely, ‘I feel like I am worthless’, ‘I et al., 2012), and identity diffusion correlates with mentalizing abilities
feel like I am a complete failure’, ‘I feel like I am a bad person’, and (De Meulemeester et al., 2017), supporting the impairment of the
‘I feel like I am evil’, in participants with BPD and a control group with mentalizing (i.e. of the human capacity to reflect on one's own and
other personality disorders. The items were administered at baseline others' internal intentional mental states such as feelings, wishes, atti-
and every 2 years for 20 years. The levels of these states were more tudes and goals) interpretation of BPD (Fonagy & Bateman, 2008;
than three times higher in the BPD participants compared with con- Semerari et al., 2005).
trols. For both groups, these states declined significantly over time, Self-concept clarity appears to have a protective effect against
and at the same rate for all states except ‘I feel like I am evil’, which self-injurious urges when negative affect is high (Scala et al., 2018). In
had a steeper decline in BPD participants. The negative perception of another study, low self-esteem was a common characteristic of
self-worth differs in both intensity and trajectory in recovered versus patients with and without self-injurious behaviours, but those who
non-recovered patients (for criteria, see article). Although the authors self-injured appeared to have an even more negative perception of
cannot determine whether the changes in these states precede, follow themselves (Almeida & Horta, 2018).
or are concurrent with recovery, they do affirm that a negative iden- Self-related emotions, such as guilt and shame, are evidently inti-
tity is associated with less effective functioning in school, work and mately related with the self-concept. For a comprehensive review of
interpersonal relationships. these in BPD, see Winter et al., 2017.
We hinted at the interplay of self-concept and self-esteem in the Concerning internalized stigma, using a self-report questionnaire,
glossary. ESE fluctuates more compared with patients with avoidant authors found it was greater in a group of patients with BPD com-
personality disorder (APD) (Lynum et al., 2008), is lower compared pared with social phobia (Rüsch et al., 2006) and also compared with
with healthy controls (HCs) (Winter et al., 2018), is highly correlated BD and attention deficit hyperactivity disorder (Quenneville
with affect instability and is related to general psychopathology et al., 2020). Rüsch et al. (2006) hypothesize that this greater sensitiv-
(Santangelo et al., 2017). ity could be linked to the shame proneness that several other studies
ESE measures might be influenced by the patients' volatile emo- describe (Unoka & Vizin, 2017) and that diminished self-esteem is a
tions (Hedrick & Berlin, 2012). Measures of ISE, however, might reveal consequence of self-stigma in their sample.
a non-reflective knowledge about the self (Winter et al., 2017). Dis-
crepancies between the two measures might indicate maladjustment
and inner tension and be positively correlated with BPD symptom 4.2 | Identity, self-concept and self-esteem in
severity, according to one study (Vater et al., 2010). bipolar disorder
A study by Hedrick and Berlin (2012) did not find any differences
in ISE, measured using an implicit association task, between subjects Contrary to BPD, studies on self-concept and identity in BD are
with BPD and HCs. But information regarding ISE lability was not col- scarce (for a detailed review, see Dyga, 2019). This is surprising
lected as the authors only measured ISE once, whereas Winter because alterations of these constructs are reported in both the clini-
et al. (2018) found lower ISE (initials preference task) compared cal practice and the few studies that investigate them.
with HCs. Most studies focus on the ‘constant synthesizing effort of the
Even though the terminology and the theories used by the studies contradictions between perceptions of oneself through different
are different, all studies agree that impaired identity and impaired affective episodes’ (Borda, 2016, p. 3).
processing of self-relevant information are present in BPD and have a For example, patients interviewed by Rusner et al. (2009) (10 peo-
relationship with BPD symptoms. In fact, the impairments in the self- ple with BD, six women, four men, aged 30–61, living at home and
structure so typical of BPD patients have been linked to other core not suffering from severe mania or depression at the time of the inter-
features of the disorder, such as interpersonal problems, impulsive view) report that the illness is ‘intertwined with one's whole being’
behaviours, chronic feelings of emptiness, emotional dysregulation and cannot be separated from one's identity. They also describe an
and self-harm. We cannot address all these relationships in detail, alternation of phases during which the identity is that of ‘bipolar and
because it would go beyond the scope of the article, but we will dis- ill’ and others during which they ‘have bipolar and are healthy’. The
cuss those that are directly mentioned and supported by the articles latter are the moments during which they feel they are ‘in contact
included in our literature search. with’ their self. But these moments are not free of pain, as they are
In the absence of a coherent self-concept, made of different iden- often ridden with guilt and shame for what they did when they had a
tities and moments in time, the individual is inevitably at the mercy of weak contact with their self and concern for their future actions. Simi-
the current moment and subsequently of impulses and emotions lar experiences were reported by patients in other studies (Jönsson
(Fuchs, 2007). The ‘chronic feelings of emptiness’ (Criterion 7, et al., 2008; Lim et al., 2004). High-functioning patients with BD inter-
DSM-5) might be the result of this: If experiences cannot be inte- viewed by Michalak et al. (2011) described having an ‘illness identity’
grated in a coherent narrative, ‘they leave only emptiness behind’ imposed on them; many described actively contrasting this socially
(Fuchs, 2007, p. 386). imposed identity with their chosen identity. Their findings show that
A correlation between high identity diffusion and interpersonal the construction of identity in BD is a transformative process, made
problems has been found (De Meulemeester et al., 2017; Sollberger of struggles and renegotiations. What is certain is that the diagnosis
6 WRIGHT ET AL.

of BD often marks a disruption in the person's life that requires a and their increased instability, possibly suggesting an underlying nega-
renegotiation of identity, influenced by the sporadic and cyclical mood tive affect and self-concept during mania (Pavlickova, Varese, Smith,
changes (Fernandez et al., 2014), that is important for recovery (Etain et al., 2013; Pavlickova, Varese, Turnbull, et al., 2013). Although
et al., 2018; Fernandez et al., 2014; Inder et al., 2008, 2011; Mansell Pavlickova, Varese, Turnbull, et al. (2013) do not distinguish between
et al., 2010; Michalak et al., 2011; Rusner et al., 2009; Sajatovic the various subtypes of mania in their sample, to explain their finding,
et al., 2008; Tse et al., 2014). we can speculate that the patients were experiencing dysphoric mania
The earlier the onset of the disorder, the greater the general or mixed mood states.
impairment (Perlis et al., 2009). The disruption of the self-concept in For clinical purposes, it is important to understand which environ-
young patients (aged 15–35 years) seems to relate to the difficulty mental stimuli determine changes in self-esteem and affect. According
in establishing continuity in the sense of self and dealing with socially to Ironside et al. (2020), some studies suggest that in people with BD,
imposed identities, based on their illness (Inder et al., 2008). Earlier self-worth is contingent on the achievement of certain goals. A study
age of onset is associated with greater co-morbidity with BPD (Moor also showed that a sample of patients with BD set more ambitious
et al., 2012). This possibly indicates that, at an early age, the illness goals than HCs (Tharp et al., 2015), independent of manic symptoms.
interferes with the development of the self, thus increasing the over- The authors hypothesize that these two characteristics might deter-
lap with BPD symptoms in this area. Co-morbidity of the two disor- mine the instability of self-esteem reported in the disorder. These
ders significantly increases the risk of self-harm behaviours that, as studies are linked to the more general theory of Behavioural Approach
we have seen in Section 4.1, are linked to a confused (Scala System (BAS) dysregulation in BD (Uroševic et al., 2008), according to
et al., 2018) and negative (Almeida & Horta, 2018) self-concept. which individuals with this disorder are hyper-responsive to reward-
Patients with bipolar disorder who are currently depressed have relevant environmental cues and this hyper-responsivity might trigger
significantly lower levels of consistency between self-actual and self- manic or depressive episodes. Contingent self-worth, autonomy, mal-
ideal domains compared with HCs and to remitted or manic patients adaptive perfectionism (Fletcher et al., 2019), ambitious goal setting
(Bentall et al., 2005): The depressed self is feared and loathed by and emphasis on goal attainment all point to a specific BAS-related
patients. Instead, during mania, there is a high consistency between cognitive style (Alloy et al., 2009).
self-actual and self-ideal or self-ought representations, meaning that Pavlova et al. (2011) elicited experiences of success or failure
this state is preferred or that discrepancies are inaccessible due to loss using an anagram task and collected implicit and explicit measures of
of insight (Silva et al., 2015). Another study (Fletcher et al., 2013) has self-esteem before and after. The results show an increased reactiv-
similar results: Hypomania ascent is described by some patients with ity of affect and ESE to failure in remitted BD patients compared
BD II as a moment during which the ideal self is present. During the with HCs, and no significant differences in ISE. This result was
hypomania descent, instead, patients fear that others will not like predicted by a history of childhood trauma, meaning that early
them and they themselves have a more negative self-concept. adverse experiences are associated with a long-term tendency to
Patients in a qualitative study describe a great fluctuation marked affective reactivity, even in response to small stressors. This
between the two extremes of self-esteem (Rusner et al., 2009): marked reactivity could possibly mediate the adverse outcomes
intense self-worth and intense self-deprecation. Great trust in one's described in patients with BD and childhood trauma, such as early-
own ability, or life on ‘high mountains’, alternates with life ‘in the val- onset, frequent episodes, rapid cycling and suicide attempts (Garno
leys’. Intense feelings of self-deprecation are accompanied by experi- et al., 2005; Leverich et al., 2002). The symptom overlap with BPD
ences of intense sadness and the idea of being worthless. They could be greater for these patients (Sansone & Sansone, 2010). Like
describe a recurring rhythm that is ‘both general and individual, con- BPD, the relationship between self-related emotions and the self-
sisting both of bottom and top levels as well as different phases (like) concept is very complex, but its description goes beyond the scope
a roller coaster with a small roller coaster inside’ (pp. 163–164). of this review (for studies on internalized shame, see Fowke
A review showed that self-esteem is significantly lower in remit- et al., 2012 and Highfield et al., 2010).
ted BD patients compared with HCs and significantly higher than that Last, several studies focus on the experience of self-stigma in
of MDD patients (Nilsson et al., 2010). Implicit and explicit measures people diagnosed with BD. This construct is correlated with QoL (Pal
are often discordant (Jabben et al., 2014; Knowles et al., 2007; Park et al., 2017; Post et al., 2018) and interpersonal relations (Sarısoy
et al., 2014) This can be due either to self-esteem instability or to a et al., 2013), has strong psychosocial and psychiatric symptom associ-
discrepancy between high standards and negative reality, according to ations (Howland et al., 2016) and contributes to treatment delay
the authors (Jabben et al., 2014). Blairy et al. (2004) found that (Latalova et al., 2013 for a review), concealment of the diagnosis to
patients in remission for at least 3 months had lower self-esteem and others (Sajatovic et al., 2008) and poor functioning, even in remitted
were less socially adjusted than HCs. patients (Au et al., 2019; Cerit et al., 2012). It appears to be less
In a study on remitted, hypomanic and depressed patients with intense than self-stigma experienced by patients with schizophrenia
BD (Pavlickova, Varese, Turnbull, et al., 2013) who were asked to (Karidi et al., 2015; Pal et al., 2017; Ran et al., 2018; for an alternative
complete 10 diary entries a day for 6 days, depression was associated finding in Taiwanese patients: Chang et al., 2016) and more intense
with high negative self-esteem and low positive self-esteem. Contrary than that experienced by patients with an anxiety disorder (Pal
to expectations, mania was associated with low mood and self-esteem et al., 2017).
WRIGHT ET AL. 7

5 | DISCUSSION stimuli (Sarkheil et al., 2019; Winter, Herbert, et al., 2015; Winter
et al., 2017) and of social feedback (e.g. Korn et al., 2016) maintain
In this practice-friendly review, we analysed and discussed publica- and increase it. Studies on explicit and ISE conducted on patients with
tions on self-concept, identity and self-esteem in bipolar disorder and BPD that use repeated measures point in the direction of a rapid fluc-
BPD. The main results are summarized in Table 1. tuation between the two extremes, high and low, but more studies
The definitions and methods used by the studies are extremely are needed (e.g. to confirm there is indeed a fluctuation and under-
heterogeneous, and therefore, they could only be reported as a narra- stand what triggers it).
tive review. In BPD, there appears to be a dichotomy between the perception
The focus of the publications differs: In BD, a great number of of being at fault, flawed, bad and aggressive (Baumann et al., 2020)
studies are on self-esteem, self-stigma and identity following diagno- and a fleeting notion of being a good and adequate person, at least
sis; in BPD, there are more studies on general identity and self- partially. Stated otherwise, if patients with BPD believe they are
concept, as can be seen in Tables 2 and 3 (appendix). One of the most unlovable and bad, and therefore undeserving of a relationship in
informative conclusions that we can draw from the reviewed studies which the other is kind and respectful, they will automatically go
is that disturbances of self-concept, identity and self-esteem are in search of distancing, abandoning and maltreating partners. Unfortu-
core features of BPD and mood-dependent features of BD. nately, in this type of negative interpersonal cycle (Dimaggio
Researchers and clinicians that adhere to different approaches all et al., 2007; Liotti, 1999; Safran & Muran, 2000; Safran & Segal, 1990)
agree on the presence of an identity disturbance in BPD. The identity that originates from the defectiveness/shame schema, they believe to
disturbance consists of not knowing who one is, in the sense that be understood for what they really are: a person undeserving and
patients with BPD do not possess a unified self-concept made of dif- unworthy of healthy affective proximity to another (Swenson, 2016).
ferent identities in time. ‘They are forever on the edge of the abyss, But these patients are also capable of establishing shorter positive
so to speak’ (Linehan, 1993, p. 36). interpersonal cycles (Dimaggio et al., 2007). These cycles activate a
Patients with BD describe an effortful process of creating a sense fleeting and unstable positive self-concept (for an in-depth discussion
of continuity that is however present. The confusion is more related of self-related emotions, see Winter et al., 2017).
to which identity is the most ‘authentic’: euthymic, euphoric or Instead, in BD, the self-concept is dichotomous during mood epi-
depressed. But it would be incorrect to describe BD as a succession sodes and relatively stable during euthymia. On the one hand, we find
of identities, without considering the impact these have at a holistic the ‘failed self’, typical of depressive episodes. It is characterized by
level, the bigger ‘roller coaster’ in Rusner et al.'s (2009) description. A vulnerability, helplessness and a feeling of not being of any value,
common feature appears to be the avoidance of feelings of anergia which can lead to intense levels of self-deprecation, anergia and anhe-
and anhedonia, which could trigger manic episodes (Mansell & donia. On the other hand, we find the ‘successful self’, typical of the
Pedley, 2008). hypomanic and manic episodes. It is characterized by a feeling of
From a qualitative point of view, there is evidence that the shifts invulnerability and inflated personal value. The person believes to be
in self-concept are closely tied to interpersonal relations in BPD. On invincible and feels energetic and gratified, both at a physical and
the other hand, the mood state appears to be the central defining fac- mental level. Childhood trauma might interfere with the development
tor for people with BD. To put it differently, changes in self-concept of the self in patients with BD; this aspect could be partially responsi-
follow an intrapsychic path in BD (e.g. Pavlickova, Varese, Turnbull, ble for the high co-morbidity with BPD (McDermid et al., 2015;
et al., 2013) and an interpersonal path in BPD (e.g. Korn et al., 2016; Pavlova et al., 2011).
van Schie et al., 2019). In the laboratory setting, self-esteem appears to be unstable and
The pervasiveness of the negative self-concept appears to be lower than that of HCs, even in remitted patients. Concerning manic
much more pronounced in BPD than BD, and biases in autobiographi- episodes, it is not clear if self-esteem is really enhanced at this time or
cal memory (Jørgensen et al., 2012), in the processing of emotional if negative evaluations are inaccessible because of the loss of insight
(Silva et al., 2015).
TABLE 1 Main results The temporal dynamics of the shifts in self-concept and self-
esteem are also likely different (rapid in BPD, slower in BD, as in shifts
BPD BD
of affect), but comparative studies are needed to prove this.
Absence of a unified self- Presence of a unified self-concept,
What struck us the most was the almost complete absence of
concept, identity diffusion confusion is related to which
identity (euthymic, euphoric, studies (except Quenneville et al., 2020 and Rüsch et al., 2006) on
depressed) is the most authentic self-stigma in BPD, in contrast to the many studies in BD (see Tables 2
Interpersonal factors trigger Intrapsychic (mood) factors trigger and 3, appendix). We only found one extra article (Grambal
changes in the self- changes in the self-concept et al., 2016 that shows that self-stigma is greater in BPD patients than
concept
patients with anxiety disorders) using the keywords ‘self-stigma AND
Trait-like negative self- State-like negative self-concept borderline personality disorder’ in several search engines. This sur-
concept
prised us because people with a diagnosis of BPD, just like people
Rapid shifts in self-concept Slow shifts in self-concept
with a diagnosis of BD, suffer recurrent hospitalizations, suicide
8

TABLE 2 Salient characteristics of the studies on borderline personality disorder considered for the review

Experimental design and other


Authors Type Sample Excl BD diagnosis Main diagnostic and clinical measures measures
Self-concept
Auerbach Quantitative 26 BPD female 33 HC female ages 13– Yes MINI-KID; SCID-II; ZAN- BPD; BDI II Self-referential encoding task
et al., 2016 22
Baumann Quantitative 29 BPD female 21 HC female Excl mania and/or SCID-II self report questionnaire Aggressiveness implicit association test;
et al., 2020 psychotic symptoms Questionnaire for Factors of
Aggressiveness (FAF)
Beeney et al., 2016 Quantitative 17 BPD female 21 HC female Yes SCID; IPDE; LEAD standard Self-aspects card sort task;
Differentiation of Self Inventory (DSI)
Dammann Qualitative 12 BPD 12 MD (79% female overall Yes SCID-I and II STIPO interview
et al., 2011 sample)
Donges et al., 2016 Quantitative 33 BPD female 33 HC female Yes SCID I e II; BDI II; BLS -95; MWT-B Speed of classification of positive and
negative adjectives
Janis et al., 2006 Quantitative 15 BPD female 28 HC female No SCID-I and II PSQ
Kanske et al., 2016 Quantitative 27 BPD 25 HC Yes MINI; SCID-II; PAI-BOR Mind-wandering paradigm that probes
self-generated thoughts during a
choice reaction time task
Korn et al., 2016 Quantitative 24 BPD female 81 HC female Yes SCID-II; MINI; BDI Character trait task in a real-life social
interaction: self and other rating,
before and after social feedback; SCL-
90-R; BSL-95; RSES; MDMQ
Meares et al., 2011 Treatment 29 BPD conversational model (CM) 31 Not specified WSS; ZDQ Constellation of BPD diagnostic
quantitative BPD TAU features; changes in constellations
(WSS) and depressive symptoms
(ZDQ) following CM
Roepke et al., 2011 Treatment 20 BPD dbt program 20 BPD waiting list Yes SCID-II; MINI; BDI; SCL-90 MSES; BSE; ESE; SCC
quantitative all female
Sarkheil et al., 2019 Quantitative 40 BPD female 20 HC female Not specified BSL-95; BLS- 23; ERQ; BDI II Self-relevance and valence rating of 90
sentences (30 negative, 30 positive,
30 neutral)
Scala et al., 2018 Quantitative 36 BPD 18 AD (total 87% female) Yes ADIS-IV-PSU; SCID-I; IPDE; ALS; MSI- Electronic survey with items assessing
BPD; SCC negative affect, self-concept clarity,
self-harm (if affirmative rating of
intensity of urge) on touchpoint
continuums
van den Heuvel Quantitative 18 BPD 34 MD 35 both 50 HC No SCID-I and II ATSS; OGT
et al., 2012
van Schie Quantitative 26 BPD 22 low self-esteem (LSE) 32 HC Only for LSE and HC RSES; MINI; IPDE-IV; SCID-II; SAPAS-SR Social feedback task: participant
et al., 2019 all female received feedback from another
female participant (confederate) based
WRIGHT ET AL.
TABLE 2 (Continued)

Experimental design and other


Authors Type Sample Excl BD diagnosis Main diagnostic and clinical measures measures
WRIGHT ET AL.

on responses to nine personal


questions and three moral dilemmas;
same feedback for all participants (15
negative, 15 intermediate, 15 positive
words) was received in MRI scanner
Vater et al., 2015 Quantitative 28 BPD 28 MD 49 HC all female Not specified MINI; SCID-II Self-descriptive card sort task yielded
three measures of self-concept:
compartmentalization, content,
relative importance of neg and pos
self-aspects
Winter, Herbert, Quantitative 30 BPD female30 HC female Yes SCID-I; IPDE; BSL-23; DBI; ASF-E Valence judgement task: positive and
et al., 2015 negative valent as well as emotionally
neutral nouns were presented with
three different referential contexts.
Subjects had to rate the valence on a
9-point scale
Winter, Koplin, & Quantitative 30 BPD female 30 HC female Yes IPDE; SCID-I; BSL-23 Participants were asked to sit for final
Lis, 2015 diagnostic questions at the end of
Winter, Herbert, et al., 2015 study.
One chair faced a mirror; another
faced the room. They could choose to
sit on whichever one. The choice was
recorded and experimenter asked if it
was intentional
Identity
De Meulemeester Quantitative 176 BPD No SCID-II; PDSQ IPO; RFQ; IIP
et al., 2017
Esguevillas Quantitative 43 BPD (81% female) Yes CGI-BPD; clinical assessment GAF; STIPO
et al., 2018 questionnaire (self-injury, suicidal
attempts, substance use, ADHD); CTQ
Gad et al., 2019 Quantitative 290 BPD (for second aim divided in 152 Yes BIS; SCID-I; DIB-R; DIP-R; BIF-R Four items from the DAS; at the 10
recovered, 138 never recovered) 70 follow-ups (each 24 months apart)
PD controls clinical and recovery status were
reassessed
Jørgensen, 2009 Quantitative 66 BPD female 65 HC female Not specified SCID-II Identity Style Inventory (ISI)
Jørgensen Quantitative 17 BPD 14 OCD 23 HC Not specified SCID-II; BDI-II; ISI Authors examined emotional valence,
et al., 2012 specificity, life script correspondence
and narrative organization of
autobiographical memories, elicited
using a life story event task + life
script task
9

(Continues)
(Continued)
10

TABLE 2

Experimental design and other


Authors Type Sample Excl BD diagnosis Main diagnostic and clinical measures measures
Lind et al., 2018 Treatment mixed 33 BPD at baseline, 23 participated in No SCID-II; BDI-II Semi-structured interviews and
methods follow-up at 12 months (91.3% questionnaires: participants were
female) 30 HC, 23 for follow-up asked to identify and describe up to
10 of their own life chapters and up to
10 of their parent's life chapters. Then
rate the emotional valence and the
causal connections of the chapter, and
for the parent's rate quality of
relationship and how sure they felt
about knowledge about the chapter.
Interviews were coded using five
codes: complexity, agency,
communion, communion fulfilment,
self and other confusion. At baseline
and follow-up
Lind et al., 2019 Mixed methods 30 BPD No SCID-II As described above + SCIM; TAS-20;
EQ; MSCEIT
Sollberger Quantitative 52 BPD No SCID-I; SCID-II SCL-90-R; BDI; STAI; IPO; association of IPO with clinical
et al., 2012 STAXI measures
Sollberger Treatment 32 BPD psychodynamic transference Yes SCID-I/P; SCID-II; BDI, STAI; STAXI IPO and clinical measures at baseline and
et al., 2014 quantitative focused psychotherapy + modules of after 12-week treatment
DBT skills training 12 BPD TAU
(79.5% female overall sample)
Walter et al., 2009 Quantitative 12 BPD 12 MDD no PD (80% female Yes SCID I; SCID II; STAI; BDI STIPO IPO
overall sample)
Wilkinson-Ryan & Quantitative 34 BPD 20 another PD 41 no PD as No Diagnosis by treating clinician; GAF Identity disturbance questionnaire
Westen, 2000 described by experienced clinicians designed for this study + GAF
(psychiatrists, psychologists, social + questions about patient's
workers) developmental history (particularly
sexual abuse), employment history,
peer relationships, social support
Self-esteem
Almeida & Quantitative 23 BPD no history self-injury behaviour No SCID II, STAXI, BIS-11, SCl-90, Global Rosenberg Self Esteem Scale (RSES) and
Horta, 2018 18 BPD history self-injury behaviour Symptom Index clinical measures
(78% female overall sample)
Hedrick & Quantitative 18 BPD (12 female) 18 DPD 35 HC Yes SCID-I; SCID-II Implicit association task (measures
Berlin, 2012 association of self and other with
positive and negative attributes); BIS-
11; Frontal Behaviour Questionnaire
(FBQ); Subjective Emotion
Questionnaire (SEQ); TCI
WRIGHT ET AL.
TABLE 2 (Continued)

Experimental design and other


Authors Type Sample Excl BD diagnosis Main diagnostic and clinical measures measures
WRIGHT ET AL.

Jacob et al., 2010 Treatment 13 BPD group therapy self-esteem Yes SCID II; MINI; BDI RSES; SSES
quantitative module 18 BPD control group all
female
Lynum et al., 2008 Quantitative 34 BPD 28 APD 17 BPD + APD (82% Yes MINI; SCID-II; SCL-90; BDI-II; GAF; CIP Index of self-esteem
female overall sample)
Santangelo Quantitative 60 BPD 60 HC Yes BDI-II; SCL-90; BSL-23 Electronic diaries completed for 4
et al., 2017 consecutive days. Current self-esteem,
valence and tense arousal levels were
reported 12 times a day in
approximately 1-hr interval
Vater et al., 2010 Quantitative 41 BPD female Not specified SCID-II; MINI Initials preference task (IPT), Heatherton
and Polivy Scale (HP); BDI; BSL-95;
SCL-90-R
Winter et al., 2018 Quantitative 31 BPD 30 HC all female Yes SCID-I; BPD section of IPDE; BSL-23; RSES; IPT; self-positivity measured with
BDI-II a self-referential processing task
where valence and referential context
were manipulated
Self-stigma
Quenneville Quantitative 69 BD 39 BPD (90% female) 136 ADHD Yes SCID II; MINI; BSL-23 ISMI; QoLB
et al., 2020
Rüsch et al., 2006 Quantitative 60 BPD 30 SP all female Yes MINI; SCID-II LPSQ; SSMIS; TOSCA-3; RSES; GSE;
SBQoL; AAQ; CES-D; SCL-90-R
Grambal et al., 2016 Quantitative 35 BPD (80% female) 30 BD 33 MD 49 No Clinical diagnosis by experienced ISMI
SC 27 AD psychiatrists using ICD-10 criteria;
demographic questionnaire; CGI
Self-compassion
Donald et al., 2018 Quantitative 19 BPD (17 female) Not specified SCID-II RAS; SCS; FSCRS
Feliu-Soler Treatment 16 BPD loving kindness/compassion Yes DIB-R; BSL-23 SCS; FSCRS; PHLMS
et al., 2016 quantitative meditations 16 BPD mindfulness
continuation training (30 of 32 total
female) all with prior 10 weeks of
mindfulness training

Note: Measures, abbreviations and references in Table 4.


Abbreviations: AD, anxiety disorder; APD, avoidant personality disorder; DBT, dialectical behaviour therapy; DPD, depersonalization disorder; OCD, obsessive–compulsive disorder; PD, personality disorder; SC,
schizophrenia; SP, social phobia; TAU, treatment as usual.
11
Salient characteristics of the studies on bipolar disorder considered for the review
12

TABLE 3

Excl BPD
Authors Type Sample diagnosis Main diagnostic and clinical measures Experimental design and other measures
Self-concept
Bentall et al., 2005 Quantitative 65 BD 22 manic/hypomanic, 24 depressed, Not specified BDI; HRSD; M-DS; YMRS PQQ
19 remitted, 23 HC
Inder et al., 2008 Treatment 6 DB I phase 1: only assessment, 10 DB I No Diagnosis by treating psychiatrist 49 hr of therapy sessions was transcribed.
qualitative phase 2: 18 months therapy completed Questions prompted sense of self and a
coding sheet was used to code self-
identity in sessions
Jabben et al., 2014 Quantitative 99 BD (86 DB I) 1,236 MD 652 HC Not specified CIDI; IDS-SR IAT; explicit self-associations on a 5-point
scale
Lam et al., 2005 Treatment 51 DB I cognitive therapy 51 DB I control No SCID; BDI; MRS SHPSS; DAS: BD; MCQ; MRC-SPS
quantitative group
Lee et al., 2010 Quantitative 54 DB I No SCID; BDI; BRMRS ASRM; SHPSS; DAS:BD; scenarios rating
task
Pavlickova, Varese, Quantitative 48 DB (28 remission, 12 depressed, 8 No HAM-D; BRMRS Experience sampling method: diaries
Smith, et al., 2013 hypomanic) completed for 6 days, 10 times a day,
with scales assessing mood, self-esteem
and styles of coping with depressive
mood
Rusner et al., 2009 Qualitative 10 DB Not specified Diagnosis by treating psychiatrist Whole-parts-whole analysis of interview
transcripts
Stange et al., 2015 Quantitative 72 DB (58% DB II, 42% cyclothymia or DB No GBI; exp-SADS-L; BDI; RRS; DEQ; CSQ; exp-SADS-C
NOS)
Tse et al., 2014 Qualitative 14 DB Not specified Diagnosis by treating psychiatrist Narrative inquiry methodology and life
charts
Identity
Fernandez et al., 2014 Qualitative 10 DB (7 DB I, 2 DB II, 1 cyclot.) No ASRM; BDI-II; SUDS; PLMI Semi structured interview schedule derived
from the PLMI scale
Fletcher et al., 2013 Mixed methods 13 DB II No MINI, MDQ, ISS Interpretative phenomenological analysis
(IPA) of interview transcripts
Pedersen et al., 2018 Quantitative 15 DB female (ICD criteria) 15 HC female Yes SWLS; PANAS; MDI; ASRM Questionnaire 10 past and future life
chapters
Self-esteem
Blairy et al., 2004 Quantitative 144 BD Not specified SADS-LA or SCAN SAS-SR; RSES
Daskalopoulou Quantitative 28 BD 16 MD 50 HC Not specified SCAN SAS-SR; RSES
et al., 2002
Johnson et al., 2000 Quantitative 31 DB I (33.3% manic, 43.3% depressed, No SCID; MHRSD; BRMS ISEL; RSES
16.6% cycling, 3.3% mixed, 3.3% not full-
blown episode)
WRIGHT ET AL.
TABLE 3 (Continued)

Excl BPD
Authors Type Sample diagnosis Main diagnostic and clinical measures Experimental design and other measures
WRIGHT ET AL.

Knowles et al., 2007 Quantitative 18 DB remitted 16 MD remitted 19 HC Not specified SCID; HAM-D; BRMS; PANAS Daily diary kept for 1 week and completed
twice each day, measuring self-esteem
and positive and negative affect; PIT
Park et al., 2014 Quantitative 19 DB manic, 27 DB euthymic 27 HC Not specified MINI; YMRS; MADRS RSES; SES; IAT
Pavlova et al., 2011 Quantitative 24 BD remitted 24 HC No SCID; MADRS RSES; NLP; CTQ; PANAS; VAS
Serretti et al., 2005 Quantitative 199 BD remitted 132 MD remitted No SCID; HAM-D RSES
Self-stigma
Au et al., 2019 Quantitative 115 DB No YMRS; HAMD; C-SSMIS; FAST; SCOS C-MSPSS; FAST; SCOS
Cerit et al., 2012 Quantitative 8 DB No BDFQ; BDI;YMRS; ISMI; MSPSS; SAI
Chang et al., 2016 Quantitative 43 DB 161 SC 98 MD No Medical records ISMI
45 AD
Çuhadar & Çam, 2014 Treatment 47 DB remitted 24 intervention Yes Diagnosis by treating psychiatrist ISMI; BDFQ
quantitative psychoeducation booklet 23 control 7
session psychoeducation program
Howland et al., 2016 Mixed methods 15 DB No SCID; BPRS; MADRS; YMRS ISMI; GSE; TRQ; content analysis of
interview transcriptions
Karidi et al., 2015 Quantitative 60 DB 60 SC No HAM-D; PANAS; GAF; CGI-BP; GCI-SP; RSES; SIMI
YMRS
Michalak et al., 2011 Mixed methods 32 DB (25 DB I 7 DB II) Not specified MINI; MSIF; HAM-D, YMRS Q-LES-Q, SAS-SR thematic analysis of
individual interview or focus group
Pal et al., 2017 Quantitative 60 DB 33 SC 30 AD all remitted No HAM-D; YMRS; SAPS; SANS; HAM-A; ISMI; RSES; SS; PS; WHOQOL-BREF
MINI; SOFAS
Post et al., 2018 Quantitative 60 DB I 77 HC No MINI; MADRS; YMRS RS-25; BELP; ISMI
Quenneville et al., 2020 Quantitative 69 BD 39 BPD 136 ADHD Yes SCID-II; MINI ISMI; QoLB
Ran et al., 2018 Quantitative 39 BD 232 SC 182 MD Not specified ICD-10-Checklist-AM ISMI demographic characteristics
Sarısoy et al., 2013 Quantitative 119 BD 109 SC Not specified DSM-IV criteria diagnosis by treating ISMI; MRQ
psychiatrist
Self-compassion
Døssing et al., 2015 Quantitative 30 BD (ICD-10 criteria) 30 HC No SCAN; ASRM; MDI; SCS; WAS; SWLS; ISMI
Fletcher et al., 2019 Quantitative 302 DB Not specified MINI; QIDS-SR; MADRS; YMRS; DASS-21 SAPS; SCS; DERS
Yang et al., 2020 Quantitative 302 DB 372 HC No MINI; DASS-21; QIDS-SR; MADRS; YMRS SCS; NTS
Illness perception
Etain et al., 2018 Quantitative 103 DB Severe BPD Diagnosis by treating psychiatrist; MADRS; YMRS; STAI; CSEI; QFS; nr. of and
YMRS < 8 and MADRS < 15 or reasons for noncompletion; knowledge
intervention delayed by 3 months about BD questionnaire; IPQ
Lim et al., 2004 Qualitative 18 DB I Not specified MINI
13

(Continues)
14 WRIGHT ET AL.

attempts and involuntary admissions to hospital, all factors that corre-


late with an elevated self-stigma (e.g. Chang et al., 2016). Stigmatiza-

Significant statements, meaning units and


fundamental structure of interview and
Experimental design and other measures

Semi-structured interview based on an

Interview based on an interview guide


tion by healthcare professionals is also very common (e.g. Koekkoek

Subjective experience of medication


integrative cognitive model of BD
et al., 2006; Ociskova et al., 2017; Treloar, 2009). We have seen that
in BPD, others' opinions of the self are important and influence one's
focus group transcriptions
own self-concept. It would not be a great leap to assume that the

interview; CGI; ITAQ


diagnosis negatively influences the self-concept, because it deter-
mines beliefs of the sort: ‘having this diagnosis is proof that I am
crazy, ill, bad’, or because others use the diagnosis against them, for
example, during conflicts. The biologization of mental illness is
thought to mitigate stigma and legitimize psychiatric symptoms
(Buchman et al., 2013), even though sometimes patients are ambiva-
lent towards medication as it strengthens their illness identity.
Regardless of research being conclusive, in the patient's mind, the
Main diagnostic and clinical measures

environmental component of BPD is thought to be greater than in


DSM-IV criteria diagnosis by treating

other disorders (such as BD), and this might increase negative self-
related emotions (guilt and shame) and worsen the idea of defective-
ness. Conversely, improper or no communication of the diagnosis is
also quite common in BPD (Sulzer et al., 2016), and this potentially
maintains identity confusion. Therefore, it is important to carry out a
MINI; HAM-D
psychiatrist

thorough communication of the diagnosis.


SCID-I

6 | IMPLICATIONS FOR TREATMENT


D I S C U S S E D I N T H E R E V I E W E D S T U DI ES
Not specified
Excl BPD
diagnosis

The reviewed studies describe ways in which a more positive and


No

No

developed self-concept could be promoted. In both conditions, recent


studies have shown that self-compassion and self-acceptance (for
BPD: Donald et al., 2018, for BD: Døssing et al., 2015; Fletcher
et al., 2019; Inder et al., 2011; Yang et al., 2020) might have the
potential to therapeutically modulate core symptoms of the disorders
and lead to recovery. Instead, self-criticism is negatively associated to
recovery in patients with BPD (Donald et al., 2018) and might increase
18 DB (11 DB I; 7 DB II)

the risk for suicidal ideation in patients with BD (Stange et al., 2015),
in synergy with a negative cognitive style and rumination. Therefore,
self-compassion should be promoted during therapy (Feliu-Soler
et al., 2016; Krawitz, 2012a, 2012b).
13 DB I
Sample

19 DB

Note: Measures, abbreviations and references in Table 5.


Abbreviations: AD, anxiety disorder; SC, schizophrenia.

7 | BPD
Mixed methods
Qualitative

Qualitative

Types of psychotherapy that have found to be effective with these


patients include dialectical behaviour therapy (DBT), mentalization-
Type

based therapy (MBT), transference-focused psychotherapy (TFP) and


schema therapy (ST) (Stoffers et al., 2012).
(Continued)

DBT can help the patient enhance self-concept clarity, as shown


Sajatovic et al., 2008

by Roepke et al. (2011) with techniques such as ‘validation (that) can


Jönsson et al., 2008
Mansell et al., 2010

be considered to be steady, self-verifying feedback from the therapist,


thus leading to a perception of coherence’ (p. 155). In a group of inpa-
TABLE 3

Authors

tients treated for 12 weeks with psychodynamic TFP with modules of


dialectical behaviour skills training, identity diffusion decreased signifi-
cantly (Sollberger et al., 2014).
WRIGHT ET AL. 15

TABLE 4 Studies on borderline personality disorder: measure names and references

Acronym Full name Authors


AAQ Acceptance and Action Questionnaire Hayes et al., 2004b Hayes, S., Strosahl, K., Wilson, K.G., Bissett,
R.T., Pistorello, J., Toarmino, D., Polusny,
M.A., Dykstra, T.A., Batten, S.V., Bergan, J.,
Stewart, S.H., Zvolensky, M.J., Eifert, G.H.,
Bond, F.W., Forsyth, J.P., Karekla, M., &
McCurry, S.M. (2004b). Measuring
experiential avoidance: A preliminary test of
a working model. Psychol Rec., 54:553–578.
DOI: 10.1007/BF03395492
ADIS-IV- Anxiety Disorders Interview Schedule for Brown et al., 1994 Brown, T. A., Di Nardo, P. A., & Barlow, D. H.
PSU DSM-IV-PSU Version (1994). Anxiety disorders interview schedule
for DSM-IV (ADIS-IV). Diagnostic
assessment instrument. New York, NY:
Oxford University Press.
ALS Affective Lability Scale Harvey et al., 1989 Harvey, P. D., Greenberg, B. R., & Serper, M. R.
(1989). The affective lability scales:
Development, reliability, and validity. Journal
of Clinical Psychology, 4:786–793. DOI:10.
1002/10974679(198909)45:5%3C786
ANGST Affective norms for German sentiment terms Schmidtke et al., 2014 Schmidtke, D.S., Schröder, T., Jacobs, A.M., &
Conrad, M. (2014). ANGST: Affective norms
for German sentiment terms, derived from
the affective norms for English words. Behav
Res Methods., 46:1108–1118. DOI: 10.
3758/s13428-013-0426-y
ASF-E Attributional Style Questionnaire Poppe et al., 2005 Poppe, P., Stiensmeier-Pelster, J., & Pelster, A.
(2005) Attributionsstilfragebogen für
Erwachsene. Göttingen: Hogrefe; 10.1111/
cei.12527
ATSS Attitudes Towards Self Scale Carver & Ganellen, 1983 Carver, C.S., & Ganellen, R.J. (1983).
Depression and components of self-
punitiveness: High standards, self-criticism,
and overgeneralization. Journal of Abnormal
Psychology, 92:330–337. DOI:10.
1037/0021-843X.92.3.330
BDI-II Beck Depression Inventory Second Ed. Beck et al., 1996 Beck, A.T., Steer, R.A., Brown, G.K. (1996):
Beck depression inventory manual, 2nd
edition.
BIF-R Revised Borderline Follow-up Interview Zanarini, 1994 Zanarini, M.C. (1994). The revised borderline
follow-up interview. Belmont, MA: McLean
Hospital.
BIS Background Information Schedule Zanarini et al., 2001 Zanarini, M.C., Frankenburg, F.R., Khera, G.S.,
& Bleichmar, J. (2001). Treatment histories
of borderline inpatients. Compr. Psychiatry,
42:144–150. DOI: 10.1053/comp.2001.
19749
BIS-11 Barratt Impulsiveness Scale Patton et al., 1995 Patton, J.H., Stanford, M.S., & Barratt, E.S.
(1995). Factor structure of the Barratt
impulsiveness scale. Journal of Clinical
Psychology, 51:768–764. DOI: 10.
1002/1097-4679(199511)51:6<678
BPD-SI Borderline Personality Disorder-Severity Giesen-Bloo et al., 2010 Giesen-Bloo, J.H., Wachters, L.M., Schouten,
Interview E., & Arntz, A. (2010). The borderline
personality disorder severity index-IV:
Psychometric evaluation and dimensional
structure. Personality and Individual
Differences, 49:136–141.
BSL-95 Borderline Symptom List Bohus et al., 2001

(Continues)
16 WRIGHT ET AL.

TABLE 4 (Continued)

Acronym Full name Authors


Bohus, M., Limberger, M.F., Frank, U.,
Sender, I., Gratwohl, T., & Stieglitz, R-D.
(2001). Entwicklung der borderline-
symptom-Liste1. PPmP—Psychother 
Psychosom  Medizinische Psychol.,
51:201–211. DOI: 10.1055/s-
2001-13281

BSL-23 Borderline Symptom List Short version Bohus et al., 2009 Bohus, M., Kleindienst, N., Limberger, M.F.,
Stieglitz, R-D., Domsalla M., Chapman A.L.,
et al. (2009). The short version of the
borderline symptom list (BSL-23):
Development and initial data on
psychometric properties. Psychopathology,
42:32–9. DOI: 10.1159/000173701
BSE Basic Self-Esteem Scale Forsman & Johnson, 1996 Forsman, L., & Johnson, M. (1996).
Dimensionality and validity of two scales
measuring different aspects of self-esteem.
Scandinavian Journal of Psychology, 37:1–
15. DOI: 10.1111/j.1467-9450.1996.
tb00635.x
CIDI Composite International Diagnostic Interview Wittchen, 1994 Wittchen, H.U. (1994). Reliability and validity
studies of the WHO-Composite
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CGI Clinical Global Impression Guy, 1976 Guy, W. (1976). “Clinical Global Impressions”.
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CGI-BPD Clinical Global Impression-Borderline Perez et al., 2007 Perez, V., Barrachina, J., Soler, J., Pascual, J.C.,
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CTQ Childhood Trauma Questionnaire Hernandez et al., 2013 Hernandez, A., Gallardo-Pujol, D., Pereda, N.,
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Factor structure, reliability. J Interpers
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Violence, 28(7):1498–518. DOI: 10.
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Steyer, R., Schwenkmezger, P., Notz, P. &
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PHLMS Philadelphia Mindfulness Scale Cardaciotto et al., 2008 Cardaciotto, L., Herbert, J. D., Forman, E. M.,
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mindfulness scale. Assessment, 15(2):204–
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PSQ Possible Selves Questionnaire Markus & Wurf, 1987 Markus, H., & Wurf, E. (1987). The dynamic
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SCID Structured Clinical Interview for DSM–IV Axis I First et al., 1997 First, M.B., Spitzer, R.L., & Williams, J.B. (1997).
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questionnaire. Washington, DC: American
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Self-Aspects Card Sort Task Shower et al., 1998 Showers, C., Abramson, L., & Hogan, M. (1998).
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Self-descriptive Card Sort Task Shower, 1992 Showers, C.J. (1992). Compartmentalization of
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SCID-II Structured Clinical Interview for DSM-III-R First et al., 1997 First, M.B., Gibbon, M., Spitzer, R.L., Williams,
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SCIM Self-concept and identity measure Kaufman et al., 2014 Kaufman, E.A., Cundiff, J.M., & Crowell, S.E.
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SCL-90 Symptom Checklist-90 Franke, 1995 Franke, G.H. (1995). Die Symptom-Checkliste
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SCS Self-Compassion Scale Neff, 2003 Neff, K. (2003). The development and
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SEQ Subjective Emotion Questionnaire Berlin & Rolls, 2004 Berlin, H.A., & Rolls, E.T. (2004). Time
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personality in selfharming borderline
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TAS-20 Toronto Alexithymia Scale Bagby et al., 1994 Bagby, M., Parker, J.D.A. & Taylor, G.J. (1994).
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TCI Temperament and Character Inventory Cloninger et al., 1994 Cloninger, C.R., Przybeck, T.R., Svrakic, D.M., &
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development and use. St-Louis, MO:
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TOSCA Test of Self-Conscious Affect Tangney et al., 2000 Tangney, J.P., Dearing, R.L., Wagner, P.E., &
Gramzow, R. (2000). The test of self-
conscious affect-3 (TOSCA-3). Fairfax:
George Mason University.
VKP Questionnaire for Personality traits (Vragenlijst Duijsens et al., 1996 Duijsens, I.J., Eurelings-Bontekoe, E.H.M., &
voor Kenmerken van de Persoonlijkheid Diekstra, R.F.W. (1996). The VKP, a self-
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Individual Differences, 20:171–182. DOI:
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WURST Wender Utah Rating Scale Ward et al., 1993 Ward, M.F., Wender, P.H., & Reimherr, F.W.
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ZAN-BPD Zanarini Rating Scale for Borderline Personality Zanarini et al., 2003 Zanarini, M.C., Vujanovic, A.A., Parachini, E.A.,
Disorder Boulanger, J.L., Frankenburg, F.R., & Hennen,
J. (2003). Zanarini rating scale for borderline
personality disorder (ZAN-BPD): A
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ZDQ Zung Depression Questionnaire Zung, 1965 Zung, W.W. (1965). A self-rating depression
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10.1001/archpsyc.1965.01720310065008

TFP and MBT directly target the self-concept. TFP (Clarkin 8 | BD


et al., 2006) aims to increase identity diffusion through different strat-
egies, tactics and techniques (such as interpretation and transference In psychotherapy, it is important to promote the integration of the ill-
analysis), MBT (Bateman & Fonagy, 2004) aims to increase the ness identity in a more general self-concept (Inder et al., 2011). Clini-
patient's ability to infer one's own and others' mental states, and ST cians should check and modify goal-attainment beliefs, particularly of
aims to increase an adaptive self-concept (healthy adult mode) those who exhibit features of sense of hyper-positive self, as they
through mode work (Young, 1999). tend to desire high mood states and could engage in behaviours that
Given that negative beliefs concerning the self are core features might ultimately lead to a manic episode (Lee et al., 2010; for a review
of BPD, it is important to conduct a thorough analysis of these beliefs of the psychological aspects of mania, see Mansell & Pedley, 2008).
during therapy and to address them using several different techniques According to Lam et al. (2005), these patients' tendency to identify
that lead to generalized and long-lasting changes. Clinical interven- with hypomanic traits as self-descriptors should be dealt with using
tions that aim to increase self-esteem (Jacob et al., 2010) and agency psychological techniques such as cognitive restructuring.
(constructed through life stories), or decrease dependency on others Psychosocial factors, such as social support as opposed to social
(Lind et al., 2018, 2019) could be beneficial for BPD patients. stigma, seem to be more relevant for the course of bipolar depression
WRIGHT ET AL. 23

TABLE 5 Studies on bipolar disorder: measure names and references

Acronym Full name Authors References


ASRM The Altman Self-Rating Mania Scale Altman et al., 1997 Altman, E.G., Hedeker, D., Peterson, J.L.,
Davis, J.M. (1997). The Altman self-rating
mania scale. Biol Psychiatry, 42:948–55.
DOI: 10.1016/S0006-3223(96)00548-3
ASRSv1.1 Adult ADHD self-report scale Adler et al., 2006 Adler, L.A., Spencer, T., Faraone, S.V., Kessler,
R.C., Howes, M.J., Biederman, J., Secnik, K.
(2006). Validity of pilot adult ADHD self-
report scale (ASRS) to rate adult ADHD
symptoms. Ann. Clin. Psychiatry, 18:145–
148. DOI: 10.1080/10401230600801077
BDI Beck Depression Inventory Beck, 1961 Beck, A.T. (1961). An inventory for measuring
depression. Arch Gen Psychiatry, 4:561–71.
DOI: 10.1001/archpsyc.1961.
01710120031004
BDFQ Bipolar Disorder Functioning Questionnaire Aydemir et al., 2007 Aydemir, Ö., Eren, _I., Savaş, H., Og
uzhanog
lu,
N.K., Koçal, N., Özgüven, H.D., et al. (2007).
Development of a questionnaire to assess
inter-episode functioning in bipolar
disorder: Bipolar disorder functioning
questionnaire. Turk Psikiyatri Derg,
18:344–52.
BELP Berliner Lebensqualitätsprofil Priebe et al., 1995 Priebe, S., Gruyters, T., Heinze, M., Hoffmann,
C., & Jakel, A. (1995). Subjective evaluation
criteria in psychiatric care-methods of
assessment for research and general
practice. Psychiat Prax, 22:140–144.
BRMRS Bech–Rafaelsen Mania Scale Bech et al., 1978 Bech, P., Bolwig, T.G., Kramp, P., Rafaelsen,
O.J. (1979). The Bech-Rafaelsen mania
scale and the Hamilton depression scale:
Evaluation of homogeneity and inter-
observer reliability. Acta Psychiatri.Scand.
59:420–430. DOI: 10.1111/j.1600-0447.
1979.tb04484.x
CIDI Composite International Diagnostic Interview Wittchen, 1994 Wittchen, H.U. (1994). Reliability and validity
studies of the WHO-composite
international diagnostic interview (CIDI): A
critical review. Journal of Psychiatric
Research, 28(1):57–84. DOI: 10.
1016/0022-3956(94)90036-1
CGI Clinical Global Impression Scale Guy, 1976 Guy, W. (Ed.) (1976). ECDEU assessment
manual for psychopharmacology. Rockville,
MD: US Department of Health, Education,
and Welfare Public Health Service Alcohol,
Drug Abuse, and Mental Health
Administration.
CGI-BP Clinical Global Impressions Scale-Bipolar Spearing et al., 1997 Spearing, M.K., Post, R.M., Leverich, G.S.,
Illness Brandt, D., Nolen, W. (1997). Modification
of the clinical global impressions (CGI) scale
for use in bipolar illness (BP): The CGI-BP.
Psychiatry Res. 73(3):159–71. DOI: 10.
1016/s0165-1781(97)00123-6
CGI-SP Clinical Global Impressions Scale-Bipolar Ill- Haro et al., 2003 Haro, J.M., Kamath, S.A., Ochoa, S., Novick,
ness adopted for schizophrenia D., Rele, K., Fargas, A., Rodríguez, M.J.,
Rele, R., Orta, J., Kharbeng, A., Araya, S.,
Gervin, M., Alonso, J., Mavreas, V.,
Lavrentzou, E., Liontos, N., Gregor, K.,
Jones P.B., & SOHO Study Group (2003).
The clinical global impression-schizophrenia
scale: A simple instrument to measure the
diversity of symptoms present in

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24 WRIGHT ET AL.

TABLE 5 (Continued)

Acronym Full name Authors References


schizophrenia. Acta Psychiatr Scand Suppl.
416:16–23. DOI: 10.1034/j.1600-0447.
107.s416.5.x
C-MSPSS Chinese version Multidimensional Scale of Chou, 2000 Chou, K-L. (2000). Assessing Chinese
Perceived Social Support adolescents' social support: The
multidimensional scale of perceived social
support. Personal Individ Differ, 28:299–
307. DOI: 10.1016/S0191-8869(99)
00098-7
CTQ Childhood Trauma Questionnaire Bernestein et al., 2003 Bernstein, D.P., Stein, J.A., & Newcomb, M.D.
(2003). Development and validation of a
brief screening version of the childhood
trauma questionnaire. Child Abuse Negl.
169–190. DOI: 10.
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WRIGHT ET AL. 31

than mania (Johnson et al., 2000). In fact, for people who have accom- maladaptive schemas, metacognitive processes, insight, autobiograph-
plished important life goals, such as forming and continuing important ical memory (in general, not identity related) and trauma, which are
personal relationships and maintaining employment, the damaging intimately related to the analysed constructs.
effects of stigma are smaller (Sajatovic et al., 2008). Self-stigma can be
targeted and reduced by psychoeducation (Çuhadar & Çam, 2014). ACKNOWLEDG MENTS
This research did not receive funding.

9 | C O N CL U S I O N S CONFLIC T OF INT ER E ST
The authors have no conflicts of interest to declare.
There is evidence in the literature of qualitative differences in self-
concept, identity and self-esteem between the two disorders. DATA AVAILABILITY STAT EMEN T
Future studies could examine factors such as environmental stim- Data sharing is not applicable to this article as no new data were cre-
uli or internal representations that might play a role in precipitating ated or analysed in this study.
changes in these constructs. Some authors have already attempted to
do so in a laboratory setting (e.g. Pavlova et al., 2011); it would also OR CID
be informative to use more ecological measures, for example, a modi- Livia Wright https://orcid.org/0000-0002-8286-0818
fied experience sampling method. Evidently, qualitative studies are Lisa Lari https://orcid.org/0000-0001-8928-3040
conducted on small numbers, and this limits their generalizability, but Stefania Iazzetta https://orcid.org/0000-0001-6922-6487
they are nonetheless a source of precious information for clinicians. Andrea Gragnani https://orcid.org/0000-0001-9129-8794
Comparative studies are greatly needed, as the great heterogene-
ity of methods, measures and theories in existing studies of the same RE FE RE NCE S
concept (see Tables 2 and 3, appendix) limits their comparability. We Alloy, L. B., Abramson, L. Y., Walshaw, P. D., Gerstein, R. K., Keyser, J. D.,
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10 | LIMITATIONS
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