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Abstract
Keywords
Chinese medicine, herbal medicine, anxiety, depression, fan zao, xin fan, constitution, calm spirit, shen.
Introduction
Practitioners of traditional East Asian medicine are strengthen Spleen qi. With patterns of deficiency causing
often unfamiliar with or else underestimate the emotional distress, the spirit (shén) will become calm
impact that heat-clearing herbs and formulas can have on when it is properly nourished. Formulas that regulate the
the mind/spirit (shén). Although these medicinals are not qi treat depression by moving stagnation. However, if we
typically defined as ‘spirit calming’, there are numerous limit our herbal vocabulary when treating the spirit to only
historical references for their clinical use in this way. This these medicinals, we neglect to honour our traditional East
article presents the practical application of heat-clearing Asian medicine (TEAM) heritage and do ourselves and our
herbs and their formula families to quiet the mind and ease patients a disservice. Such a perspective - essentially seeing
suffering, in order to improve practitioners’ clinical the spirit as something separate from the body - might
precision and expand their repertoire of methods. be seen to reflect something of a Western reductionist
When diagnosing and treating psycho-emotional way of thinking. In fact, if the diagnosis is appropriate,
disorders such as anxiety and depression, practitioners heat-clearing herbs and formulas can deliver a genuinely
often rely on medicinals and formulas from two broad constitutional treatment that deals with emotional
categories: the ‘calm the spirit’ category and the ‘regulate qi’ suffering by treating the whole person - not merely treating
category. Formulas that calm the spirit are primarily tonics symptoms of emotional distress.
used to nourish Heart blood and yin, tonify Kidney yin and Similarly, the clinical importance of the six fǔ bowels is
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Using Herbs That Clear Heat to Calm the Spirit
often devalued. The five zang viscera are often considered the constitution of the patient, the nature of each herb and
more precious than than fǔ. However, the fǔ have a critical its formula family, and the disease pattern treated by it.
role in the generation and distribution of yin, blood and jīn
yè fluids throughout the body. Without the fǔ, we would Xīn fán, fán zào and anxiety
die of malnutrition. Fǔ heat patterns can also cause severe When investigating the effect of herbal medicine on
psycho-emotional disturbance, especially those centred psycho-emotional imbalance, it is important to be aware
on yánɡ mínɡ heat. Bitter heat-clearing herbs can balance of the traditional Chinese medical concept of fán 烦
and promote digestive qi, and simultaneously create space (vexation or irritability). According to the Practical
for quiet yin reflection. To illustrate this point, we can look Dictionary of Chinese Medicine,2 there are approximately 90
to the description of Dà Huáng in the Shén Nóng Bĕn Căo references to fán in the Shāng Hán Lùn. Thirteen variations
Jīng (Divine Husbandman’s Classic of Materia Medica): ‘… of fán are listed, including fán jīng bù ān (vexation and
scouring and flushing the intestines and stomach; pushing susceptibility to fright), fán yuan (vexation and low spirits)
out the old and making the new arrive … calming and and fán zào yì nù (vexation, agitation and irascibility). Xīn
harmonizing the five zang organs.’1 The clinical strategies fán 心烦 (heart vexation) refers to a feeling of unrest
of clearing, draining or purging stagnant heat to reset the or irritability focused in the heart or chest region. Xīn
body and mind and facilitate ‘renewal’ have been tried and fán is often observed in patterns of excess or deficiency
tested by numerous physicians throughout history. heat. With increasing heat, xīn fán can progress to a
pattern that involves actual physical agitation of the limbs
Constitution called fán zào 烦躁 (vexation and agitation). The former is
a subjective symptom, while the latter is an objective sign.
References to the spirit-calming effects of medicinals Although they are different, they are often considered as
stretch back as far as one, as they usually occur
the Shén Nóng Bĕn Căo in tandem and share the
Jīng. When using herbs
to calm the spirit, it is
Xīn fán can progress to a pattern that same disease mechanisms.
In clinical practice, we
important to be aware of involves actual physical agitation might encounter a patient
the constitutional aspect
of herb prescribing. Just
of the limbs called fán zào 烦躁 who is unable to settle
down, feels nervous and
as one might diagnose a (vexation and agitation). tense, and tends to be
person in terms of the five reactive. They experience
phases as having a wood an inability to concentrate
or fire constitution, the Shāng Hán Lùn (Treatise on Cold and are forgetful. Western diagnoses that fall under the
Damage) offers a path to constitutional treatment rooted category of fán zào include anxiety, attention deficit
in medicinals and formulas. Using this system, a herb hyperactivity disorder (ADHD), bipolar disorder, even
reflects a type of person and their way of being in the post-traumatic stress disorder (PTSD) can fall under
world, as well as a predisposition towards developing this umbrella term. Fán zào can also be associated with
certain diseases. No one has championed these theories neurological diseases such as Parkinson’s disease and
more than Dr. Huang Huang of Nanjing. Huang’s system hyperthyroidism. Finally, drug and alcohol withdrawal
presents constitutional patterns that are reflected in the can result in fán zào.3
character of specific herbs, their associated formulas and It is easy to overlook the importance of fán in the clinic.
the diseases treated by them. Therefore, we might say After years of clinical practice, I felt dissatisfied with the
that the behaviour of a person with a Chái Hú (Bupleuri results I was achieving treating anxiety, depression and
Radix) constitution reflects a Chái Hú imbalance and insomnia using the formulas I had been taught as a student.
predisposes them to develop Chái Hú diseases. Moreover, In those days, Chinese herbal education did not focus
they will be treated with Chái Hú formulas. Understanding much on the classics, as is common now. When I began
the patterns and formulas presented in the Shāng Hán to study the herbs, formulas and pattern presentations of
Lùn and Jīn Guì Yào Lüè (Essentials from the Golden the Shang Han Lun, which introduced me to the concept
Cabinet) in this way creates clarity, simplifying the most of fán, I had a decisive paradigm shift that clarified
complex cases to their fundamental component: the qi my understanding of how to diagnose and treat these
dynamic. In this way, for the right person at the right time, disorders. Since then, I have effectively applied these
heat-clearing medicinals can be profoundly spiritually concepts to many of my treatment strategies to alleviate
nourishing. The key to clinical success is to understand anxiety.
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Using Herbs That Clear Heat to Calm the Spirit
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Journal of Chinese Medicine | Issue123 | June 2020
Using Herbs That Clear Heat to Calm the Spirit
The pulse that indicates that Huáng Lián should be used the mind is Huáng Lián Ē Jiāo Tāng (Coptis and Ass Hide
is typically slippery and rapid. The tongue is red with a Gelatin Decoction):
firm or tough appearance. There may be red prickles and
a thick yellow, dry coating. If the tongue is not coated, or Huáng Lián 黄连 Coptidis Rhizoma 12g
the tongue body pale, then either Huáng Lián should only
be used cautiously in a harmonising formula, or not at all. Huáng Qín 黄芩 Scutellariae Radix 6g
In comparison, in a Shí Gāo presentation the face will be Bái Sháo 白芍 Paeoniae Radix Alba 6g
red. The Huáng Lián complexion may be pale, but the lips,
tongue and throat are red. Ē Jiāo 阿胶 Asini Corii Colla 9g
Two key Huáng Lián formulas treat patterns of heat above Jī Zǐ Huáng 鸡子黄 Vitellus Galli 2 yolks
and cold below. Bàn Xià Xiè Xīn Tāng (Pinellia Decoction to
Drain the Epigastrium) being the most important example: Huáng Lián Ē Jiāo Tāng (Coptis and Ass Hide Gelatin Decoction)7
Huáng lián 黄连 Coptidis Rhizoma 3g This formula treats xū fán (deficiency vexation). This
pattern can be diagnosed by palpating the epigastrium,
Huáng qín 黄芩 Scutellariae Radix 6g inferior to the sternum. The patient will feel discomfort on
Rén shēn 人参 Ginseng Radix 6g palpation, although the practitioner will not feel resistance.
In contrast, when the epigastrium of the Bàn Xià Xiè Xīn
Bàn xià 半夏 Pinelliae Rhizoma 9g Tang patient is palpated, it will feel painful to the patient and
Gān jiāng 干姜 Zingiberis Rhizoma 6g the practitioner will also feel resistance. Symptoms of xū fán
include irritability and anxiety, with a sensation of fullness
Zhì gān căo 炙甘草 Glycyrrhizae Radix praeparata 2g in the chest that prevents the patient from lying down. Their
Dà zăo Z大枣 Jujubae Fructus 4pc complexion is often pale (reflecting blood deficiency) with
red or dark lips (reflecting heat). The formula employs
Bàn Xià Xiè Xīn Tāng (Pinellia Decoction to Drain the Epigastrium) a sophisticated pairing of Huáng Lián and Ē Jiāo. Huáng
Lián drains Heart fire to eliminate vexation but is drying. Ē
A related formula is Huáng Lián Tāng (Coptis Decoction): Jiāo enriches Kidney water, yet it is cloying. When water is
nourished, it can ascend to the Heart. When fire is directed
Huáng Lián 黄连 Coptidis Rhizoma 6g downwards, the Kidneys are warmed. Thus, the formula
treats the pattern of Heart and Kidneys not communicating.
Gān Jiāng 干姜 Zingiberis Rhizoma 6g The final formula discussed here that uses Huáng Lián
Guì Zhī 桂枝 Cinnamomi Ramulus 6g to calm the spirit is Huáng Lián Wēn Dǎn Tāng (Warm Gall
Bladder Decoction with Coptis):
Bàn Xià 半夏 Pinelliae Rhizoma 9g
Zhì Gān 炙甘草 Glycyrrhizae Radix praeparata 6g Bàn Xià 半夏 Pinelliae Rhizoma 6g
Căo
Fú Líng 茯苓 Poria 6g
Dà Zăo 大枣 Jujubae Fructus 4pc
Chén Pí 陈皮 Citri reticulatae Pericarpium 9g
Huáng Lián Tāng (Coptis Decoction)
Zhú Rú 竹茹 Bambusae Caulis in taeniam 6g
These formulas use a similarly sophisticated combination Zhǐ Shí 枳实 Aurantii Fructus immaturus 6g
of warm and cold ingredients to correct the ascending Gān Căo 炙甘草 Glycyrrhizae Radix 3g
and descending of the qi mechanism, so that yin and yang
are harmonised. By clearing heat from the Heart, Huáng Dà Zăo 大枣 Jujubae Fructus 3 pcs
Lián allows the spirit to become calm, settled and focused. Shēng 生姜 Zingiberis Rhizoma recens 5 slices
The Shén Nóng Bĕn Căo Jīng states, ‘Consumed over a long Jiāng
time, it staves off forgetfulness.’6 For this reason, Huang
Huáng Lián Wēn Dăn Tāng (Warm Gall Bladder Decoction with Coptis)
Huang suggests that Huáng Lián can be used to improve
memory.
One of the best examples of the use of Huáng Lián to calm The actions of this formula are to clear phlegm-heat,
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Using Herbs That Clear Heat to Calm the Spirit
harmonise the Stomach, quell nausea and vomiting, with attention deficit hyperactivity disorder (ADHD). Dr.
clear the Gall Bladder and regulate qi. The indications Hsu writes that Shí Gāo and its representative formula, Bái
include dizziness, nausea, dream-disturbed sleep, glomus, Hŭ Tāng (White Tiger Decoction), can be used for delusions.8
restlessness, being easily startled, irritability and bitter taste There are three key aspects to a Shí Gāo presentation:
in the mouth. The tongue is red with a thick yellow coat, • The complexion of the patient is red or ruddy; they may
and the pulse is slippery or wiry. look haggard.
Although Bàn Xià is discussed in textbooks as being • Because heat has injured the fluids, the tongue is dry with
primarily used to treat phlegm and alleviate nausea, a thin coating. The pulse will be flooding and big.
its use is actually much broader than this and includes • The patient looks robust, tends to be sweaty and their
anxiety. This is evidenced by the actions and indications voice may be loud.
of Wēn Dǎn Tāng (Warm Gall Bladder Decoction). When
combined with Huáng To further expand on
Lián, it is especially useful the Shí Gāo tongue, even
for treating anxiety and ... the patient not only experiences though there is great heat,
irritability. When I studied vexation and agitation but also - the tongue does not have
at the Xi Yuan Hospital in a coating because there is
Beijing, Wēn Dǎn Tāng was because this is a syndrome of not substantial material
the most commonly used great heat - incoherent speech accumulation in the body.
formula in the psychiatry- If the tongue is coated
neurology department. or mania. and the abdomen is firm
A person with a Wēn upon palpation, then the
Dǎn Tāng presentation was often simply diagnosed as focus moves towards a Dà Huáng presentation, as this
being ‘neurotic’. This was not the pejorative declaration is indicated to treat yánɡ mínɡ patterns ‘with form’ (i.e.
that is understood in the West, but merely a statement material accumulation). Shí Gāo formulas are inappropriate
that the disease has affected the patient’s nervous system. if the pulse is thready, wiry or deep, there is no thirst and
The formula’s actions hinge on the application of bitter, the patient is not sweaty.
descending herbs that clear heat from the Gall Bladder. Shí Gāo is included in several formulas that treat
It may seem that there are no spirit-calming herbs in the wheezing due to Lung heat, most notably Má Xìng Shí Gān
formula. However, the formula deals with the core pathology Tāng (Ephedra, Apricot Kernel, Gypsum and Licorice
of phlegm-heat as it impacts the mind. The Bàn Xià person is Decoction) and Dà Qīng Lóng Tāng (Major Green Dragon
wide-eyed, anxious, easily startled, fearful and nervous. Bàn Decoction). The Shén Nóng Bĕn Căo Jīng states that it treats
Xià presentations might be part of post-traumatic stress counterflow qi below the Heart, fright and panting, dry
disorder. According to Dr. Huang, when using Bàn Xià for mouth and tongue, hardness and pain in the abdomen,
psycho-spiritual disorders we should use large doses, up to and eliminates evil ghosts. In terms of specific illnesses, this
30 grams daily. Smaller, more standard doses are used to paints a vivid picture of both asthma as well as the shortness
harmonise the Stomach and quell nausea. of breath associated with extreme anxiety, amongst others.
An excellent formula example of the use of Shí Gāo to
Shí Gāo treat the spirit can be found by studying Zhú Yè Shí Gāo
Shí Gāo is the primary medicinal for treating yánɡ mínɡ Tāng (Lophatherum and Gypsum Decoction):
disorders. Symptoms include what is colloquially referred
to as the ‘the big four’: big fever, big sweat, big thirst and Dàn Zhú Yè 淡竹叶 Lophatheri Herba 12g
big pulse. The person feels subjectively hot and prefers cold
food and drinks - essentially mirroring the experience of a Shí Gāo 石膏 Gypsum Fibrosum 30g
heatwave in the summer. Encountering a Shí Gāo type is to Bàn Xià 半夏 Pinelliae Rhizoma 10g
meet a loud, boisterous, short-tempered, red-faced person.
When the Stomach fǔ is affected, there may be symptoms of Mài Mén Dōng 麦门冬 Ophiopogonis Radix 18g
Stomach fire, such as reflux and thirst. When the channel is Rén Shēn 人参 Ginseng Radix 6g
affected, we might see frontal headache, toothache, bleeding
gums and inflammation. Furthermore, the patient not only Gān Căo 甘草 Glycyrrhizae Radix 6g
experiences vexation and agitation but also - because this is a Gēng Mǐ 粳米 Oryzae sativae Semen 15g
syndrome of great heat - there may be incoherent speech or
mania. Milder Shí Gāo presentations are encountered in those Zhú Yè Shí Gāo Tāng (Lophatherum and Gypsum Decoction)
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Using Herbs That Clear Heat to Calm the Spirit
Indications for this formula include insomnia, nervous type is that of a robust, muscular person who enjoys alcohol.
exhaustion, oppression of the chest, parched lips, Since Gé Gēn releases the muscle layer, it treats muscular
restlessness, stifling sensation, a dry, red tongue with a tension, especially in the neck and shoulders. There may
thin coating, and a rapid-empty pulse. The formula treats also be thirst, diarrhoea and acne.
the sequelae of fever with insomnia and irritability. The An excellent example of a Gé Gēn formula that can treat
patient looks thin, dry and anxious, and may be suffering the spirit can be found in the formula Gé Gēn Qín Lián Tāng
from chronic illness. It can also be used to treat the side (Kudzu, Scutellaria and Coptis Decoction):
effects of chemotherapy. The chief herb is Dàn Zhú Yè,
which enters the Heart channel to clear vexation. Shí Gé Gēn 葛根 Puerariae Radix 24g
Gāo’s sweet and acrid properties vent the heat and re-order
the qi dynamic. Bàn Xià clears heat from the Gall Bladder, Huáng Lián 黄连 Coptidis Rhizoma 9g
relieves anxiety and harmonises the Stomach. Mài Mén Huáng Qín 黄芩 Scutellariae Radix 9g
Dōng generates fluids, nourishes the yin, and calms the
spirit. Rén Shēn and Gān Căo tonify the qi and generate Zhì Gān Căo 炙甘草 Glycyrrhizae Radix praeparata 6g
fluids, while Gēng Mǐ protects the stomach. This formula
Gé Gēn Qín Lián Tāng (Kudzu, Scutellaria and Coptis Decoction)
uses 30 grams of Shí Gāo, which is a lower dose than one
would use when treating a yánɡ mínɡ fever, suggesting that
this formula does not address full heat. In contrast, Bái Hŭ This formula releases the exterior and clears yánɡ
Tāng White Tiger Decoction can use up to 90 grams. By mínɡ interior heat to treat foul-smelling or explosive
using a smaller dose of Shí Gāo combined with Mài Mén diarrhoea, burning sensation of the anus after defecation,
Dōng, the actions are redirected towards nourishing yin irritability with a feverish sensation in the chest and
fluids and clearing lingering heat. When I use this formula, epigastrium and thirst, with a yellow tongue coating
I tend reduce the dose further, usually to 15-18 grams. Of and a rapid pulse. It is thus often used to treat hot-type
course, lingering emotions can also generate heat that, acute gastroenteritis and ulcerative colitis. In addition to
given the right constitution, might be treated with this these traditional applications, the formula is an effective
formula. method for treating
vexation and agitation,
Gé Gēn Gé Gēn can be understood in headache, muscle spasms,
Gé Gēn is one of the more dizziness and anxiety with
compelling herbs to terms of its opening, mobilising and heat. Because Gé Gēn also
learn, both as a Chinese softening actions. lowers blood pressure
medicinal as well as for its and improves cerebral
biochemistry. There is a circulation, the formula
large body of research showing that the major bioactive might be used to address the cognitive and behavioural
ingredients in Gé Gēn are the isoflavones puerarin, changes caused by hardening of the arteries and related
daidzein and genistein. The herb is cardioprotective, cerebral-vascular disorders. In clinical practice, I have used
antihypertensive, antipyretic, neuroprotective, this formula for the agitation and outbursts that occur in
antispasmodic, and more.9 Gé Gēn is sweet, acrid and people with Alzheimer’s disease. For this situation, we
cool. It enters the Spleen and Stomach channels. Its chief can modify the formula with medicinals to invigorate the
actions are to raise the clear yang qi of the Stomach, blood, such as Chì Sháo (Paeoniae Rubra Radix), Mŭ Dān
release the muscles and generate fluids to alleviate thirst. Pí (Moutan Cortex) and Táo Rén (Persicae Semen).
Furthermore, Gé Gēn can lower blood pressure and treat
headaches and dizziness.10 Zhī Zǐ
A key to understanding a Gé Gēn constitution lies in Zhī Zĭ is bitter and cold. It enters the Heart, Lungs,
its ability to treat alcohol toxicity. If we extrapolate on Stomach, Liver and Triple Burner. It clears heat from all
this idea of intoxication, we can expand it to include three burners, draining it through urination. Additionally,
symptoms of dizziness, confusion and clouded thinking. it clears damp-heat jaundice and is used to treat damp-
Therefore, Gé Gēn can be used when people experience heat lìn syndrome. It cools the blood and relieves toxicity
a lack of grounding or clarity. Gé Gēn allows clear yang to and thus can be used when heat causes blood to move
reach the head and is one of the best medicinals for clearing recklessly. Zhī Zĭ neither clears exterior heat, nor does
the mind. Gé Gēn can be understood in terms of its opening, it clear hard, clumped heat. Zhī Zĭ particularly treats
mobilising and softening actions. The typical Gé Gēn body constrained heat - often causing stifling oppression in the
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Using Herbs That Clear Heat to Calm the Spirit
chest - by draining it through urination. Zhāng Zhòng-jǐng When other signs and symptoms match, I often modify this
says that Zhī Zĭ ‘resolves anguish and vexation in the heart formula to treat children with difficulty sleeping.
and depressed heat bind’.11 When Zhāng uses the term A widely used formula that uses Zhī Zĭ to calm the spirit
'anguish', he means a feeling of harassment to the point is Jiā Wèi Xiāo Yáo Săn (Modified Rambling Powder)
where the patient cannot calm down, along with shallow
and rapid breathing. Chái Hú 柴胡 Bupleuri Radix 9g
In addition to obvious signs of heat such as red eyes,
being easily angered and a bitter taste in the mouth, Dāng Guī 当归 Angelicae sinensis Radix 9g
there are other important signs and symptoms of a Zhī Bái Sháo 白芍 Paeonia Radix alba 9g
Zĭ presentation. When palpating the abdomen, there is
often pain and discomfort under the sternum. Look for Bái Zhú 白术 Atractylodis 9g
macrocephalae Rhizoma
tightness, rigidity and a lack of yielding below the heart,
as well as a subjective sensation of fullness in the chest and Fú Líng 茯苓 Poria 9g
epigastrium. A hallmark sign of a Zhī Zĭ pattern is revealed
Zhì Gān 炙甘 Glycyrrhizae Radix 3g
if the practitioner quickly and firmly palpates just below Căo 草 praeparata
the sternum; if this elicits pain or discomfort that startles
the patient, then this strongly suggests a Zhī Zĭ pattern Bò Hé 薄荷 Menthae haplocalycis 6g
Herba
presentation.
Shēng Jiāng 生姜 Zingiberis Rhizoma 3-5 slices
recens
Zhī Zǐ 栀子 Gardeniae Fructus 9g
Mŭ Dān Pí 牡丹 Moutan Cortex 6g
Dàn Dòu Chǐ 淡豆豉 Sojae Semen praeparatum 9g 皮
Zhī Zǐ Chǐ Tāng (Gardenia and Prepared Soybean Decoction) Zhī Zǐ 栀子 Gardeniae Fructus 6g
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Journal of Chinese Medicine | Issue123 | June 2020
Using Herbs That Clear Heat to Calm the Spirit
agitation. He uses it to treat insomnia and irritability. He reflective space within the patient, allowing them to grow
likes to combine it with Zhī Zĭ for this purpose.14 Huang and flourish.
created the formula the formula Bā Wèi Chū Fán Tāng
(Eight Flavor to Eliminate Vexation Decoction), which
uses it in this way to great effect:15 Cara O. Frank, L.O.M., Dipl. O.M., is an acupuncturist,
herbalist and educator who has been in practice since 1983.
Hòu Pò 厚朴 Magnoliae Officinalis Cortex 10g She is also the founder of China Herb Company, created
in 1991 to meet the need for high quality custom Chinese
Bàn Xià 半夏 Pinelliae Rhizoma 10g herbal formulas. She has also founded and directed Chinese
Fú Líng 茯苓 Poria 10g herb departments at two acupuncture schools. Cara is the
author of TCM Case Studies: Eye, Ear, Nose and Throat
Zǐ Sū 紫苏梗 Perillae Caulis 10g Disorders. She lives and practises in Philadelphia, where
Gěng
she runs Six Fishes Healing Arts, with two locations and a
Lián Qiào 连翘 Forsythiae Fructus 15g special focus on Chinese herbal medicine. She is the creator
of many Chinese herbal products, including her signature
Huáng 黄芩 Scutellariae Radix 10g
Qín ‘Little Fishes’ formulas for children.
Using herbs that clear heat to calm the spirit and settle the
mind has significantly improved my therapeutic results,
whether the chief complaint is anxiety or depression, or
associated symptoms such as an inability to concentrate
or insomnia. With conscientious treatment, immediate
and lasting results can be achieved. When the heat that has
caused the spirit to be unsettled clears, the mind is left
calm and focused. The patient feels centred, cooled and
present. Thus, treatment can cultivate a clear, still and
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