NIM : 821423026 CLASS : S1-C FARMASI SUPPORTING LECTURER: Dr. Suleman Bouti, S.Pd, M.Hum
BACHELOR OF PHARMACY STUDY PROGRAM
PHARMACEUTICAL DEPARTMENT FACULTY OF SPORTS AND HEALTH GORONTALO STATE UNIVERSITY 2023 BAB I INTRODUCTION Mycoplasma pneumonia is a type of bacteria that causes upper respiratory tract diseases, especially pneumonia. This bacterium is unique because it does not have a cell wall, which makes it resistant to several types of antibiotics. Mycoplasma pneumonia infection can cause symptoms such as cough, fever, chest pain, and shortness of breath. It is important to identify and treat with appropriate antibiotics as it can cause serious complications if left untreated. Mycoplasma pneumonia is a common cause of atypical pneumonia, which is often referred to as "walking pneumonia" because the symptoms are mild so that a person is still able to carry out activities. The infection usually spreads through airborne droplets and can affect people of all ages, but is more common in teenagers and young adults. Diagnosis of mycoplasma pneumonia often involves a physical examination, clinical history, and laboratory tests such as serology or PCR. Treatment involves the use of antibiotics such as azithromycin or doxycycline. Although symptoms are often mild, keep in mind that this infection can cause complications such as lung inflammation, pericarditis, or problems with the nervous system. Prevention efforts include maintaining hand hygiene, avoiding contact with sick people, and adhering to respiratory hygiene measures. Awareness of mycoplasma pneumonia is important for proper management and prevention of the spread of infection. It is also important to remember that mycoplasma pneumonia often has a long incubation period, during which a person can be a carrier without showing symptoms. Therefore, early recognition and appropriate treatment are very important in reducing the risk of spreading this disease. In addition, because mycoplasma pneumonia is resistant to several types of commonly used antibiotics, such as beta-lactams, choosing the right antibiotic according to medical guidelines is key in treating this infection. When symptoms such as fever, cough, or difficulty breathing appear, immediately consult a medical professional for appropriate diagnosis and treatment. An in-depth understanding of mycoplasma pneumonia not only helps in treating individuals but also contributes to efforts to prevent the spread of this disease in society. Keep in mind that although mycoplasma pneumonia generally has a good prognosis, some individuals, especially those with already compromised health, can experience serious complications. These complications can include deeper lung infections, lung damage, or autoimmune reactions. It is also important to understand that a vaccine to prevent mycoplasma pneumonia is not yet commonly available, so preventive measures such as maintaining personal hygiene and avoiding high exposure to sick individuals remain crucial. Given the nature of this bacterium that can develop in unpredictable ways, research is ongoing to understand more about mycoplasma pneumonia and to develop more effective treatment and prevention strategies. Additionally, keep in mind that mycoplasma pneumonia can also occur seasonally, with spikes in cases occurring more frequently in the winter and early spring. Awareness of these patterns can help authorities and health professionals take proactive steps to manage and control the spread of infections. It is important to educate the public about the symptoms of mycoplasma pneumonia, as well as the promotion of healthy lifestyle behaviors and prevention of respiratory infections in general. Steps such as routine influenza vaccination can also help reduce the risk of complications when a person is exposed to mycoplasma pneumonia. BAB II DISCUSSION According to a journal article from Margaret R Hammerschlag, Current opinion in infectious diseases 14 (2), 181-186, 2001, Mycoplasma pneumoniae is a frequent cause of community-acquired respiratory infections in children and adults. Although the organism is felt to be the most frequent ‘atypical’pathogen responsible for community-acquired pneumonia in adults, the prevalence of M. pneumoniae varies greatly from study to study, depending on the population and the diagnostic methods used. Recent studies have found the prevalence of M. pneumoniae in adults with pneumonia to range from 1.9 to over 30%. M. pneumoniae is also a frequent cause of outbreaks of respiratory disease in institutional settings. However, the diagnosis of M. pneumoniae infection is hampered by the lack of standardized, rapid, specific methods. This problem was illustrated by the results of an investigation of an outbreak of M. pneumoniae infection in a federal training facility. Accurate diagnosis required a combination of polymerase chain reaction and serology, as IgM antibodies were not present early in the course of the infection in many patients. Several papers evaluating various serological and polymerase chain reaction assays were published during the period of this review. An assessment of the actual performance of these tests was also hampered by the lack of standardized comparative methods. M. pneumoniae is susceptible in vitro to macrolides, tetracyclines and quinolone antibiotics; however, data are limited on the microbiological efficacy of these agents. Several pneumonia treatment studies were published during this period, practically all of them based the diagnosis of M. pneumoniae infection on serology; different methods and criteria were used in each study, and thus the microbiological efficacy could not be assessed. The Infectious Disease Society of America recently stated in their revised Practice Guidelines for the Management of Community-Acquired Pneumonia in Adults that, as there were no diagnostic tests available that reliably and rapidly detect M. pneumoniae, therapy must usually be empirical. And supported by journal articles from Ken B Waites, Deborah F Talkington Clinical microbiology reviews 17 (4), 697-728, 2004, Mycoplasma pneumoniae is a unique bacterium that does not always receive the attention it merits considering the number of illnesses it causes and the degree of morbidity associated with it in both children and adults. Serious infections requiring hospitalization, while rare, occur in both adults and children and may involve multiple organ systems. The severity of disease appears to be related to the degree to which the host immune response reacts to the infection. Extrapulmonary complications involving all of the major organ systems can occur in association with M. pneumoniae infection as a result of direct invasion and/or autoimmune response. The extrapulmonary manifestations are sometimes of greater severity and clinical importance than the primary respiratory infection. Evidence for this organism's contributory role in chronic lung conditions such as asthma is accumulating. Effective management of M. pneumoniae infections can usually be achieved with macrolides, tetracyclines, or fluoroquinolones. As more is learned about the pathogenesis and immune response elicited by M. pneumoniae, improvement in methods for diagnosis and prevention of disease due to this organism may occur. BAB III CLOSING Mycoplasma pneumonia is a bacterium that causes upper respiratory tract disease. It is important to seek medical care if you experience symptoms such as cough, fever, and shortness of breath. Keep your hands clean and avoid contact with infected people to prevent the spread. Consult a healthcare professional for proper diagnosis and treatment. It is also important to remember that mycoplasma pneumonia can affect anyone, but is more common in children and young adults. Diagnosis is usually made through a physical examination, blood tests, and other tests. Treatment involves certain antibiotics, and it is recommended to follow the doctor's instructions and take the full amount of medication even if the symptoms have subsided. Additionally, adequate rest and hydration can aid recovery. If symptoms persist or worsen, contact a healthcare professional immediately. After recovery, it is necessary to maintain lung health by avoiding exposure to cigarette smoke and air pollution. Creating a clean and healthy environment around you can also help prevent the spread of infections. Talking to your doctor about pneumonia vaccination is also a wise step to protect yourself from more serious lung infections. Continue to monitor your health and immediately consult a medical professional if suspicious symptoms arise. REFERENSI https://scholar.google.com/scholar? hl=id&as_sdt=0%2C5&q=mycoplasma+pneumoniae+&btnG=#d=gs_qabs&t=17014981599 24&u=%23p%3DflkKASkIRfQJ https://scholar.google.com/scholar? hl=id&as_sdt=0%2C5&q=mycoplasma+pneumoniae+&btnG=#d=gs_qabs&t=17014982216 93&u=%23p%3DLSRDFBIOOvcJ
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