Product name: KE-45-TS 1/9

Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

SAFETY DATA SHEET

1. Chemical and company identification

Name of chemical (Product KE-45-TS
name)
SUPPLIER
COMPANY NAME Shin-Etsu Chemical Co., Ltd.
Silicone Division
ADDRESS 4-1, Marunouchi 1-chome, Chiyoda-ku, Tokyo 100-0005, JAPAN
TELEPHONE NUMBER 03-6812-2400
FAX NUMBER 03-6812-2412
SDS PREPARER Quality Assurance Department （Gunma Complex）
TELEPHONE NUMBER 027-385-2172
EMERGENCY 027-385-2172（Holiday/Nighttime：027-385-2111)
E-MAIL msds_s@shinetsu.jp
Recommended use of the chemical and restrictions on use
Intended use RTV rubbers
RTV rubber for electrical, electronic and general industry (coating) ,
RTV rubber for electrical, electronic and general industry (gluing and sealing)
Restrictions on use Industrial use only.

2. Hazards identification
GHS classification
Physical hazards Flammable liquids Category 2
Health hazards Acute toxicity, inhalation Category 4
Skin corrosion/irritation Category 2
Serious eye damage/eye irritation Category 2
Sensitization, skin Category 1B
Carcinogenicity Category 1B
Reproductive toxicity Category 1A
Reproductive toxicity Effects on or via lactation
Specific target organ toxicity, single exposure Category 1 (central nervous system)
Specific target organ toxicity, single exposure Category 3 respiratory tract irritation
Specific target organ toxicity, single exposure Category 3 narcotic effects
Specific target organ toxicity, repeated Category 1 (central nervous system, kidney)
exposure
Environmental hazards Hazardous to the aquatic environment, acute Category 2
hazard
Hazardous to the aquatic environment, Category 3
long-term hazard
*Hazards not stated here are "Not classified", "Not applicable" or "Classification not possible".
GHS label elements
Symbols

Signal words Danger

Hazard statement
Highly flammable liquid and vapor. Harmful if inhaled. Causes skin irritation. Causes serious eye
irritation. May cause an allergic skin reaction. May cause cancer. May damage fertility or the
unborn child. May cause harm to breast-fed children. Causes damage to organs (central nervous
system). May cause respiratory irritation. May cause drowsiness or dizziness. Causes damage to
organs (central nervous system, kidney) through prolonged or repeated exposure. Toxic to
aquatic life. Harmful to aquatic life with long lasting effects.

SDS Japan (English)

Product name: KE-45-TS 2/9
Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

Precautionary statement
Prevention Obtain special instructions before use. Do not handle until all safety precautions have been read
and understood. Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Keep
container tightly closed. Ground/bond container and receiving equipment. Use explosion-proof
electrical/ventilating/lighting equipment. Use only non-sparking tools. Take precautionary
measures against static discharge. Do not breathe dust/fume/gas/mist/vapors/spray. Use only
outdoors or in a well-ventilated area. Wear protective gloves/protective clothing/eye
protection/face protection. Do not eat, drink or smoke when using this product. Avoid contact
during pregnancy/while nursing. Wash thoroughly after handling. Contaminated work clothing
should not be allowed out of the workplace. Avoid release to the environment.
Response In case of fire: Use appropriate extinguishing media for extinction. IF ON SKIN (or hair):
Remove/take off immediately all contaminated clothing. Rinse skin with plenty of soap and water.
If skin irritation or rash occurs: Get medical advice/attention. IF INHALED: Remove person to
fresh air and keep comfortable for breathing. Call a POISON CENTER or doctor/physician if you
feel unwell. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses,
if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention.
If exposed or concerned: Get medical advice/attention. Get medical advice/attention if you feel
unwell. Take off contaminated clothing and wash it before reuse.
Storage Store in a well-ventilated place. Keep container tightly closed. Keep cool. Store locked up.
Disposal Dispose of contents/container in accordance with local/regional/national/international regulations.
Other hazards This product reacts with water , moisture or humid air to evolve following compounds:
Methylethylketoxime
Emergency overview May be ignited by heat, sparks or flames. Harmful if inhaled. Causes damage to organs. May
cause drowsiness and dizziness. May cause cancer. Causes serious eye irritation. Causes skin
irritation. May cause irritation to the respiratory system. May cause an allergic skin reaction. May
cause reproductive effects. Dangerous for the environment if discharged into watercourses.

3. Composition/information on ingredients
Substance or mixture Mixture
(Silicone solution)
Gazette notification
Components CAS Number ENCS no. ISHL no. Concentration (%)
Toluene 108-88-3 (3)-2 (3)-2 40 - 50
Methyloximesilane 22984-54-9 (2)-2039 (2)-2039 1-3
Alkoxysilane 919-30-2 (2)-2061 (2)-2061 0.1 - 0.3
Methylethylketoxime(Impurity) 96-29-7 (2)-546 (2)-546 0.1 - 1

Gazette notification
Decomposition CAS Number ENCS no. ISHL no. Concentration (%)
Methylethylketoxime 96-29-7 (2)-546 (2)-546
All components are listed on ENCS under CSCL.

4. First aid measures

If inhaled Remove victim to fresh air and keep at rest in a position comfortable for breathing. Oxygen or
artificial respiration if needed. Call a POISON CENTER or doctor/physician if you feel unwell.
If on skin Remove contaminated clothing immediately and wash skin with soap and water. For minor skin
contact, avoid spreading material on unaffected skin. If skin irritation or rash occurs: Get medical
advice/attention. Take off contaminated clothing and wash before reuse.
If in eyes Rinse immediately with plenty of water for at least 15 minutes. Remove contact lenses, if present
and easy to do. Continue rinsing. Get medical attention if irritation develops and persists.
If swallowed Rinse mouth. Get medical attention immediately.
Protection of first-aid Take off all contaminated clothing immediately. IF exposed or concerned: Get medical
responders advice/attention. Ensure that medical personnel are aware of the material(s) involved, and take
precautions to protect themselves. Wash contaminated clothing before reuse.
Notes to physician Treat symptomatically.

5. Fire-fighting measures
Extinguishing media
Extinguishing media to avoid
Specific hazards
Water fog. Foam. Dry chemical powder. Carbon dioxide (CO2).
Do not use a solid water stream as it may scatter and spread fire.
By heating and fire, harmful vapors/gases may be formed.
Nitrogen oxides. (corrosive)

SDS Japan (English)

Product name: KE-45-TS
Company name: Shin-Etsu Chemical Co., Ltd.
Special fire fighting
procedures
Protection of fire-fighters
6. Accidental release measures
Personal precautions,
protective equipment and
emergency measures
Environmental precautions
Methods or materials for
containment and cleaning up
7. Handling and storage
Handling
Technical measures (e.g.
Local and general
ventilation)
Safe handling advice
Contact avoidance
measures
Hygiene measures
Storage
Safe storage conditions
Safe packaging materials
8. Exposure controls/personal protection
Occupational exposure limits
Japan. OELs - ISHL. (Workplace Environment Assessment Standards)
Components
TOLUENE (CAS 108-88-3)
Japan. OELs - JSOH (Japan Society of Occupational Health: Recommendation of Occupational Exposure Limits)
Components
Toluene (CAS 108-88-3)
US. ACGIH Threshold Limit Values
Components
Toluene (CAS 108-88-3)
Vendor guide
Decomposition
Methylethylketoxime (CAS
96-29-7)
3/9
Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022
In case of fire and/or explosion do not breathe fumes. Move containers from fire area if you can do
so without risk. Water runoff can cause environmental damage.
Firefighters must use standard protective equipment including flame retardant coat, helmet,
gloves, rubber boots, and self-contained breathing apparatus.
Keep unnecessary personnel away. Local authorities should be advised if significant spillages
cannot be contained. Do not touch or walk through spilled material. Ventilate closed spaces before
entering them. Wear appropriate personal protective equipment.
Prevent further leakage or spillage if safe to do so. Avoid release to the environment.
ELIMINATE all ignition sources (no smoking, flares, sparks or flames in immediate area). Keep
combustibles (wood, paper, oil, etc.) away from spilled material.
Large Spills: Stop the flow of material, if this is without risk. Dike the spilled material, where this is
possible. Cover with plastic sheet to prevent spreading. Prevent entry into waterways, sewer,
basements or confined areas.
Small Spills: Clean surface thoroughly to remove residual contamination.
Never return spills in original containers for re-use.
Vapors may form explosive mixtures with air. All equipment used when handling the product must
be grounded. Use non-sparking tools and explosion-proof equipment.
Provide adequate ventilation.
Obtain special instructions before use. Do not handle until all safety precautions have been read
and understood. Do not smoke. Take precautionary measures against static discharges. Wear
appropriate personal protective equipment. When using, do not eat, drink or smoke. Wash hands
thoroughly after handling. Avoid release to the environment. Do not empty into drains.
Use care in handling/storage. Do not breathe mist or vapor. Pregnant or breastfeeding women
must not handle this product. Avoid contact with skin. Avoid contact with eyes. Avoid prolonged
exposure.
Refer to section 10: stability and reactivity.
Wash hands before breaks and immediately after handling the product. Contaminated work
clothing should not be allowed out of the workplace. Handle in accordance with good industrial
hygiene and safety practice.
Store locked up. Keep away from heat, sparks and open flame. Store in a well-ventilated place.
Keep out of the reach of children. Store in a cool, dry place out of direct sunlight.
Keep in original container.
Type Value
TLV 20 ppm
Type Value
TWA 188 mg/m3
50 ppm
Type Value
TWA 20 ppm
Type Value
STEL 10 ppm
TWA 3 ppm
SDS Japan (English)
Product name: KE-45-TS 4/9
Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

Biological limit values

Japan. BELs - JSOH (Japan Society of Occupational Health: Recommendation of Occupational Exposure Limits Based
on Biological Monitoring)
Components Value Determinant Specimen Sampling Time
Toluene (CAS 108-88-3) 0.6 mg/l Toluene Blood *
0.06 mg/l Toluene Urine *
* - For sampling details, please see the source document.
ACGIH Biological Exposure Indices
Components Value Determinant Specimen Sampling Time
Toluene (CAS 108-88-3) 0.3 mg/g o-Cresol, with Creatinine in *
hydrolysis urine
0.03 mg/l Toluene Urine *
0.02 mg/l Toluene Blood *
* - For sampling details, please see the source document.
Exposure guidelines
Japan JSOH OELs: Skin designation
Toluene (CAS 108-88-3) Can be absorbed through the skin.
Engineering measures Explosion-proof general and local exhaust ventilation. Provide eyewash station.
Pay attention to ventilation such as local exhaust, mechanical and/or door open for at least 24
hours after application.
Personal protective equipment
Respiratory protection When workers are facing concentrations above the exposure limit they must use appropriate
certified respirators.
Hand protection Wear protective gloves.
Eye protection Wear safety glasses with side shields (or goggles).
Skin and body protection Wear suitable protective clothing.

9. Physical and chemical properties

Appearance
Form Liquid.
Color Translucent.
Odor Solvent odor
Melting point/Freezing point No data
Boiling point, initial boiling 230 °F (110 °C) [Toluene]
point, and boiling range
Flammability Highly flammable liquid
Flammability limit - lower (%) 1.4 % v/v [Toluene]
Flammability limit - upper (%) 6.7 % v/v [Toluene]
Flash point 41 °F (5 °C) Closed Cup
Auto-ignition temperature Not available.
Decomposition temperature Not available.
pH Not measurable (Refer to water solubility)
Viscosity 750 mPa·s ( 25 °C )
Solubility (Water) Not soluble
Partition coefficient Not applicable
(n-octanol/water)
Vapor pressure 3.7 kPa ( 25 °C ) [Toluene]
Vapor density 3.1 (air=1) [Toluene]
Evaporation rate > 1 (Butyl Acetate=1)
Specific gravity 0.96 ( 25 °C )
Molecular weight Not applicable
Particle size Not available.

10. Stability and reactivity

Reactivity No hazardous reaction known under normal conditions of use, storage and transport.

SDS Japan (English)

Product name: KE-45-TS 5/9
Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

Chemical stability Stable at normal conditions.

Possibility of hazardous
reactions
Conditions to avoid
Incompatible materials
Hazardous decomposition
products
Hazardous polymerization does not occur.
None specific.
Water, moisture. Strong oxidizing agents.
This product reacts with water, moisture or humid air to evolve following compounds:
Methylethylketoxime.
Thermal breakdown of this product during fire or very high heat condition may evolve the following
hazardous decomposition product:
Carbon oxides and traces of incompletely burned carbon compounds. Silicon dioxide. Nitrogen
oxides. Formaldehyde .

11. Toxicological information

Acute toxicity
Components Species Test Results
Alkoxysilane (CAS 919-30-2)
Acute
Dermal
LD50 Rabbit 4290 mg/kg
Oral
LD50 Rat 1570 - 3650 mg/kg
1780 mg/kg
Toluene (CAS 108-88-3)
Acute
Dermal
LD50 Rabbit 12124 mg/kg
14.1 ml/kg
Inhalation
LC50 Mouse 400 ppm, 24 Hours
Oral
LD50 Rat 5000 mg/kg
2.6 g/kg
Decomposition Species Test Results
Methylethylketoxime (CAS 96-29-7)
Acute
Dermal
LD50 Rabbit > 1000 mg/kg (Male and female)
Inhalation
Vapor
LC50 Rat > 4.83 mg/l, 4 hours (Male and female)
Oral
LD50 Rat > 900 mg/kg (Male and female)
2326 mg/kg (Male)
Skin corrosion/irritation Causes skin irritation. [Toluene] [Methylethylketoxime]
SKIN-RABBIT : 5mg/24Hr SEVERE [Alkoxysilane]
Serious eye damage/eye Causes eye irritation. [Toluene]
irritation Causes serious eye irritation. [Methyloximesilane]
EYE-RABBIT : 0.75mg/24Hr SEVERE [Alkoxysilane]
Causes serious eye damage. [Methylethylketoxime]
Respiratory or skin sensitization
Respiratory sensitization Not available.
Skin sensitization May cause an allergic skin reaction. [Methyloximesilane] [Alkoxysilane ]
[Methylethylketoxime]
Germ cell mutagenicity Negative(Ames Test) [Alkoxysilane]
Carcinogenicity May cause cancer. [Methylethylketoxime]

SDS Japan (English)

Product name: KE-45-TS
Company name: Shin-Etsu Chemical Co., Ltd.
ACGIH Carcinogens
Toluene (CAS 108-88-3)
IARC Monographs. Overall Evaluation of Carcinogenicity
Toluene (CAS 108-88-3)
Reproductive toxicity
Specific target organ toxicity -
single exposure
Specific target organ toxicity -
repeated exposure
Aspiration hazard
Other information
12. Ecological information
Ecotoxicological data
Components
Alkoxysilane (CAS 919-30-2)
Aquatic
Fish
Toluene (CAS 108-88-3)
Aquatic
Crustacea
Fish
Decomposition
Methylethylketoxime (CAS 96-29-7)
Aquatic
Fish
Ecotoxicity
Persistence and degradability
Bioaccumulation
Mobility in soil
Hazardous to the ozone layer
6/9
Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022
A4 Not classifiable as a human carcinogen.
3 Not classifiable as to carcinogenicity to humans.
May damage fertility or the unborn child. May cause harm to breastfed babies.
[Toluene]
May cause damage to the following organs.
Central nervous system. Respiratory tract irritation. Narcotic effects. [Toluene]
Upper respiratory tract. Narcotic effects. [Methylethylketoxime]
May cause damage to the following organs through prolonged or repeated exposure:
Central nervous system. Kidneys. [Toluene]
Hematopoietic system. [Methyloximesilane]
Blood. Hematopoietic system. [Methylethylketoxime]
May be fatal if swallowed and enters airways. [Toluene]
Additional Information
Methyl Ethyl Ketoxime (MEKO). Material will generate MEKO on exposure to humid air gradually.
Male rodents exposed to MEKO vapor at high concentration throughout their lifetime developed
liver cancer. But relevance to humans is uncertain now. Please read the detail information to
MEKO below
Skin Irritation ;Causes mild irritation. Can be absorbed through the skin.
Eyes Irritation ;Causes severe irritation.
Acute Oral Tox. ;LD50(rat)= >900mg/kg.
Acute Dermal Tox. ;LD50(rabbit)= >1000mg/kg.
Acute Inhalation Tox.;LC50(rat) > 4.83mg/l/4Hr
Inhalation Tox. ;Shows narcotic action at high concentration. May produce blood effects
Skin Sensitization ;Positive(guinea pig)
Neurotoxicity ;High dose can produce transient and reversible change in neurobehavioral
function.
Carcinogenicity ;Liver carcinomas were observed in a lifetime inhalation study (ca.2 years)
in which mice and rats were exposed.
Mutagenicity ;Not considered mutagenic based on several in vitro and vivo studies.
Other Chronic Study ;Degenerative effects on the olfactory epithelium of nasal passages
occured in a concentration related manner in males and females of mice and rats at MEKO
concentration of 15, 75 and 375ppm. The significant change in hematological parameters were
observed at 404ppm concentration.
Workplace Environmental Exposure Level; Vendor guide ; 3ppm(TWA), 10ppm(STEL),
AIHA WEEL ; 10ppm(TWA)
Species Test Results
LC50 Oryzias latipes > 1000 mg/l, 48 hr
EC50 Water flea (Daphnia magna) 5.46 - 9.83 mg/l, 48 hours
LC50 Coho salmon,silver salmon 5.5 mg/l, 96 hours
(Oncorhynchus kisutch)
Species Test Results
LC50 Fathead minnow (Pimephales promelas) 777 - 914 mg/l, 96 hours
Toxic to aquatic life. Harmful to aquatic life with long lasting effects. [Toluene]
Harmful to aquatic life. [Methylethylketoxime]
Causes easily hydrolysis in water or atmosphere. [Alkoxysilane]
No data available.
No data available.
No data available.
SDS Japan (English)
Product name: KE-45-TS
Company name: Shin-Etsu Chemical Co., Ltd.
13. Disposal considerations
Local disposal regulations
14. Transport information
International regulations
IATA
UN number
UN proper shipping name
Transport hazard class(es)
Class
Subsidiary risk
Packing group
Environmental hazards
ERG Code
Special precautions for user
Other information
Passenger and cargo
aircraft
Cargo aircraft only
IMDG
UN number
UN proper shipping name
Transport hazard class(es)
Class
Subsidiary risk
Packing group
Environmental hazards
Marine pollutant
EmS
Special precautions for user
Transport in bulk according to
Annex II of MARPOL 73/78 and
the IBC Code
IATA; IMDG
National regulations
Emergency Response Guide
Number
15. Regulatory information
Industrial Safety and Health Act
Specified substances regulation
Class 1 designated chemical substances
Not regulated.
7/9
Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022
Not hardening substance : Incinerate. Incinerator should be appropriately equipped for silica and
other fine powder which the product will generate in incineration. Workers should wear
appropriate personal protective equipment(s) such as respirator.
Hardening substance : Bury or incinerate. Incinerator should be appropriately equipped for silica
and other fine powder which the product will generate in incineration. Workers should wear
appropriate personal protective equipment(s) such as respirator.
Contract with a disposal operator licensed by the Law on Disposal and Cleaning. Do not allow this
material to drain into sewers/water supplies. Dispose of contents/container in accordance with
local/regional/national/international regulations.
UN1866
Resin solution flammable
3
-
II
No.
3L
Read safety instructions, SDS and emergency procedures before handling.
Allowed with restrictions.
Allowed with restrictions.
UN1866
RESIN SOLUTION flammable
3
-
II
No.
F-E, S̲-E̲
Read safety instructions, SDS and emergency procedures before handling.
This product is not intended to be transported in bulk.
Follow regulation in section 15 for domestic transportation.
128
SDS Japan (English)
Product name: KE-45-TS 8/9
Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

Specified substances regulation

Class 2 designated chemical substances
Not regulated.
Class 3 designated chemical substances
Not regulated.
Organic solvent regulation
Class 1 organic solvents
Not regulated.
Class 2 organic solvents
TOLUENE
Class 3 organic solvents
Not regulated.
Notifiable substances
TOLUENE 40 - 50 %
γ-AMINOPROPYLTRIETHOXYSILANE(From April 1, 2025.) 0.10 - 0.30 %
Labeling substances
TOLUENE
Poisonous and Deleterious Substances Control Act
Specified poisonous substances
Not regulated.
Poisonous substances
Not regulated.
Deleterious substances
Not regulated.
Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc.
Class I specified chemical substances
Not regulated.
Class II specified chemical substances
Not regulated.
Monitoring chemical substances
Not regulated.
Priority Assessment Chemical Substances (PACs)
TOLUENE
Law concerning Pollutant Release and Transfer Register
Law concerning Pollutant Release and Transfer Register (Until March 31, 2023)
Specified class 1 substances (substance name, ordinance number and content)
Not applicable
Class 1 substances (substance name, ordinance number and content)
TOLUENE Ordinance No. 300 48 %
Class 2 substances (substance name, ordinance number and content)
Not applicable
Law concerning Pollutant Release and Transfer Register (After April 1, 2023)
Specified class 1 substances (Control number, substance name and content)
Not applicable
Class 1 substances (Control number, substance name and content)
【300】TOLUENE 48 % (Toluene)
Class 2 substances (Control number, substance name and content)
Not applicable
Fire Service Act Class 4 Group 1 oils (Non-water soluble) Hazard rank II
Ship Safety Law, Dangerous Flammable liquid materials
Goods Marine Transport and
Storage Rule
Air Law, Enforcement Rule Flammable liquid materials
Explosives Control Act Not applicable.
High Pressure Gas Safety Act Not applicable.
Act on Prevention of Marine Not applicable.
Pollution and Maritime
Disaster

SDS Japan (English)

Product name: KE-45-TS 9/9
Company name: Shin-Etsu Chemical Co., Ltd. Reference #: 0949S0 / 07 Version #: 05 Revision date: 10-13-2022

16. Other information

Bibliography HSDB® - Hazardous Substances Data Bank
IARC Monographs. Overall Evaluation of Carcinogenicity
National Toxicology Program (NTP) Report on Carcinogens
ACGIH Documentation of the Threshold Limit Values and Biological Exposure Indices
Japan Society for Occupational Health, Recommendation of Occupational Exposure Limits
JIS Z 7252:2019 Classification of chemicals based on “Globally Harmonized System of
Classification and Labelling of Chemicals (GHS)”
JIS Z 7253:2019 Hazard communication of chemicals based on GHS - Labelling and Safety Data
Sheet (SDS)
Japan Chemical Industry Association (JCIA) GHS Guideline, June 2019
This safety data sheet was prepared in accordance with JIS Z 7253:2019. This information is offered in good faith as typical values
and not as a product specification. No warranty, expressed or implied, is hereby made. The recommended industrial hygiene and safe
handling procedures are believed to be generally applicable. However, each user should review these recommendations in the
specific context of the intended use and determine whether they are appropriate.
This product has been designed, manufactured and developed solely for general industrial use only. This product is not designed for,
intended for use as, or suitable for, medical, surgical or other particular purposes. Users have the sole responsibility and obligation to
determine the suitability of this product for any application, to make preliminary tests, and to confirm the safety of this product for their
use. Users must never use this product for the purpose of implantation into the human body and/or injection into humans.
Version number 05
Revision date 10-13-2022

SDS Japan (English)