ISBB LONG TEST
Ans: Fc
Ans: MHC
Opsonins are:
Ans: NK cell
Ans: Autoimmune disorders (Type 3
Hypersensitivity)
- Involves in complement activition
Ans: IgA
IgA2 crosses over in the lumen from the tissues.
Ans: Svedberg
Ans: Fc
- Thru Fc antigens are connected with
effector cells “serves as a bridge”
Ans: All are possible answers
Ans: IgM antibodies predominate
Ans: Predominant in a secondary (anamnestic)
response
IgM: primary
IgG: secondary
Ans: Antibody response is often below the level of
detection in early stages.
Ans: No change in the level of specific antibody
No chagne
Ans: CD4+, CD8+, CD3+
Ans: CD2
Ans: CD10; CD20
Ans:
Ans: Vitronectin
Ans: She has an autoimmune disease with Ag-Ab
activity
Ans: Allograft
Ans: HLA-B8
Ans: Class II molecules have presented bacterial
antigen CD4+ T cells
Ans: CSF-VDRL
Ans: Reheated to 56C for 10 minutes
Ans: Streptolysin O
Ans: Antistreptolysin O inhibits the reagent
streptolysin O, resulting in no hemolysis
*Keyword: INHIBITION TEST
Ans: none of the above
Ans: Serologic techniques
Ans: Acute Hepatitis B
*If IgG is present also, then it can be considered as
CHRONIC.
Ans: HBV is A DNA virus, whereas the other are
RNA viruses
Ans: Release result: Negative for HIV
Ans: Past Infection/Infection resolved
Ans: Figure 1
Ans: P. falciparum
Ans: All are advantages of antigen detection
methods
Ans: High titer of DNa Ab
Ans: Gamma globulin-coated particles
Ans: SLE
- Homogeneous, even pattern
Ans: ALP
Ans: NK cells
Ans: CA 15-3 and CA 549
Ans: Type 2
Ans: T cells and macrophages
Ans: Delta checks
Ans: Light Scattering
Ans: Precision
Ans: CD3 & CD4
Ans: R’r’
Ans: An A2 person may form anti-A1; an A1
person will not form anti-A1
Lectin: Dolichos biflorus
Ans; Group A persons
ABO Discrepancy: Type 2 (weak reacting antigens)
Ans: Wash the cells with warm saline, autoadsorb
the serum at 4C
Ans: D–/D–
Ans: Often implicated in delayed HTR
- “notorious blood group that is associated
with delayed HTR”, because of its low
immunogenicity.
Ans: Anti-K
- Antibodies implicated in HDN must be an
IgG and well-expressed upon birth.
Kell: less common, less severe
ABO: most common
Rh: most severe
Ans: Anti-N
Kidd, Kell, Duffy - IgG (rhessus)
LIPMAN - IgM
Ans: Bga, Bgb, Bg’
Ans: Dosage
Homozygous has Higher density, hence it is also
has higher agglutination reaction.
Ans: All are possible
Ans: HBIG
HBIG: 12 months
Rubella: 4 weeks
Influenza and YF: 2 weeks
Ans: Diastolic pressure of 110 mmHg
Ans: a triathlete with a pulse of 45
Ans: Check and reposition the needle if necessary;
if blood flow does not resume, withdraw the needle
Ans: Recombinant HPV
Vaccines developed by recombinant technology
carry NO DEFERRAL PERIOD.
Ans: 3.0 x 10^11, ph must be >6.2
Single donor platelet: plateletpheresis
Random donor platelet: pooled platelet
Ans: <5 x 10^6
Posibly done:
Pretrans
Bedside
Post trans (during storage)
Ans: Must be issued within 24 hours
Ans: Frozen RBC
Ans: Platelet require constant agitation at 20C -
24C
Ans: light spin followed by a hard spin
Ans: Buffy coat removal
Ans: FFp must be prepared within 24 hrs of
collection
Ans: plasma pH
Ans: Idiopathic thrombocytopenic purpura (cause
by antiplatelet antibody)
*FFP other choice
Ans: 4 hours
When individual cryo units are pooled in an OPEN
SYSTEM, expiration time is 4 HOURS
Ans: units of group O, Rh-negative RBC
Ans: functional platelet abnormalities
Ans: Patient is deficient in IgA and develops IgA
antibodies via sensitization from transfusion or
pregnancy
- Washed RBC is transfused to remove IgA
among protein in the plasma of donor
- Little to none plasma blood component is
used
Ans; Febrile nonhemolytic
- Increased temperature
- DAT negative
*Allergic: symptoms related to anaphylactic
reactions
*Delayed hemolytic: DAT positive
Ans: Anti-k
- Public antigen: commonly seen in most
people.(anti-k, antiKpb, anti-jsb)
Ans: perform saline replacement technique
Elution: for isolation
Ans: 7 days
Ans: –
Ans: Duffy
Enzyme treatment: removal of antigen
Ans: All of the above
Neutralization: removal of antibody
Anti i: breast milk
Anti-xg: women
Anti lewis: secretors
Ans: Anti-Lub
*Other are IgM
Ans: Run enzyme panel
Ans: Ab attaches to RBCs at 4C and causes
hemolysis at 37C
Ans: Anti-e
Ans: rosette test will be positive
Ans: % of fetal cells present x 50
Ans: mother has not been previously immunized to
the D antigen
Ans: Transfusion of antigen-positive cells to the
mother
Ans: Discard the unit
Ans: 85%
Ans: Known D-negative cells
Ans: Presensitized O negative cells “check cells”
Additional Notes:
