Colchicine drug
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?Colchicine
Colchicine is a drug used to treat inflammation and relieve pain.
It is commonly used to relieve the symptoms of gout, as it
affects the body's response to uric acid. One of the symptoms of
gout that colchicine helps relieve is swelling of the extremities
.or severe pain in the extremities
The drug is also used to treat Familial Mediterranean Fever, but
the mechanism of action is still unknown and under scientific
research. Familial Mediterranean Fever is a hereditary
inflammatory condition that causes bouts of fever, pain, and
.swelling in the stomach, lungs, and joints
It should be noted that colchicine is not a pain reliever and
cannot be used to treat pain resulting from conditions other
than gout or Familial Mediterranean Fever. It is classified as an
anti-gout drug and works by stopping the natural processes that
.cause swelling and other symptoms of gout and fever
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How to use Colchicine
:When using the medicine, the following is recommended
You should continue taking Colchicine even if the patient's
.symptoms improve
If you forget to take a dose, you should take it as soon as you
remember, but if it is time for the next dose, avoid doubling
.the dose
The medicine may reduce the body's immunity, so you should
.try to stay away from causes of infection
The medicine reduces the number of platelets responsible for
blood clotting, so injuries and wounds should be avoided due
.to the difficulty of wound healing
The treatment is dispensed according to the doctor's
.instructions and under his supervision
Laboratory blood tests should be followed up, and periodic
.tests of kidney and liver functions should be done
The medicine may cause some side effects that require a
:doctor's visit, including
.Nausea-1
.Diarrhea-2
.Vomiting-3
.Muscle pain or weakness-4
.Numbness or tingling in the fingers or toes -5
.Bruising or abnormal bleeding-6
Sore throat, fever, chills and other signs of infection. 8- -7
.General weakness or fatigue. 10- Paleness
The drug is used with caution and under the supervision of a
:doctor in the following cases
Pregnancy, there are not enough studies on the safety of use,
.and a doctor should be consulted
Breastfeeding, it is not recommended to use colchicine during
breastfeeding, because there are not enough studies on the
.safety of use
.Children under 18 years of age
Elderly people, they are more sensitive to the side effects of
this drug, especially muscle weakness, pain and numbness,
.tingling and numbness in the fingers
Blood diseases, including: low white blood cell count, low
platelets, and aplastic anemia, as colchicine increases the risk
.of blood disorders, and thus may worsen the condition
Digestive system diseases, the risk of damage to the tissues of
the digestive system caused by colchicine may be higher in
patients suffering from alcoholism or gastrointestinal diseases.
The doctor will adjust the doses in the event of the mentioned
.conditions
If you want to perform a dental procedure, it is recommended
to postpone the use of colchicine, or delay the medical
procedure to avoid any complications, as colchicine causes
.blood disorders
As mentioned earlier, the drug is not used as a pain reliever
.for other conditions, as colchicine is not a pain reliever
Also, it should be noted that colchicine may reduce sperm
production, which may affect males' ability to reproduce, and
it is advisable to consult a doctor before using the drug
:Colchicine is contraindicated in the following cases
.Hypersensitivity to any component of the drug
Kidney and liver diseases, as colchicine is metabolized in the
liver and kidneys together, and therefore, when suffering from
kidney or liver disorders, the metabolism of the drug will
decrease, and thus its levels in the blood will increase, which
.may increase its serious side effects
Concomitant use of colchicine with drugs that inhibit CYP3A4
or P-glycoprotein in patients with kidney or liver diseases
