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Patho Excel 2

The document outlines various medical topics related to pathology, including cell injury, inflammation, diseases of immunity, neoplasia, genetic disorders, and disorders of blood cells. It categorizes conditions based on severity and provides detailed descriptions of different diseases, their pathogenesis, and laboratory diagnostics. Additionally, it covers specific organ systems such as the heart, lungs, gastrointestinal tract, liver, pancreas, urinary system, and reproductive systems, highlighting key differences and classifications within each area.

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0% found this document useful (0 votes)
38 views24 pages

Patho Excel 2

The document outlines various medical topics related to pathology, including cell injury, inflammation, diseases of immunity, neoplasia, genetic disorders, and disorders of blood cells. It categorizes conditions based on severity and provides detailed descriptions of different diseases, their pathogenesis, and laboratory diagnostics. Additionally, it covers specific organ systems such as the heart, lungs, gastrointestinal tract, liver, pancreas, urinary system, and reproductive systems, highlighting key differences and classifications within each area.

Uploaded by

garima1022003
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as XLSX, PDF, TXT or read online on Scribd

Key

R- robbins

various types of patient consent

cell injury and cell death


2 stars
dbw:- reversible and irreversible call injury
free radical injury
dbw:- coagulative and liquefactive necrosis
dbw:- coagulative and caseous necrosis
dbw:- apoptosis and necrosis- fig 2.4-R
apoptosis
extrinsic and intrinsic pathway of apoptosis
1 star
cell injury
necrosis:- types
dbw caseous and gangrenous necrosis
fat necrosis
3/4th star
dbw dry and wet gangrene
1/2th star
dbw autolysis and necrosis

tissue repair
2 star
dbw dystrophic and metastatic calcification
factors affecting wound healing
dbw healing by 1 intention and 2 intention- fig 3.29- R
dbw granuloma and granulation tissue
complications of wound healing
steps in scar formation-R-pg-105,106,107- fig 3.28
1 star
dystrophic calcification

inflammation
3 stars
diff b/w acute and chronic inflammation
describe events of acute inflammation-cellular,vascular,chemotaxis+ components of acute inflammation,causes
complement system
2 stars
define inflammation and different stimuli
role of opsonins in phagocytosis/phagocytosis
chemical mediators of acute inflammation
cytokines
chronic inflammation
events in chronic inflammation
development of tubercular and foreign body granuloma
1 star
morphological types of acute inflammation+fate
IL1-TNF
granulomatous inflammation
diff b/w epithelial and epitheloid cells
diff b/w tumor giant cell and langhans giant cell
kinins- R-92
fever-R-102
diagrams-R-fig 3.1-72,3,4-77,table3.3,3.8-82,fig 3.17-95,3.20-98,

hemodynamic disorders,thrombosis and shock


3 stars
diff b/w transudate and exudate
congestive splenomegaly
thrombus
factors responsible for venous thrombus/ arterial thrombus
endothelial injury in the formation of thrombus
fate of thrombus
diff b/w red infarct and white infarct
septic shock

2 stars
causes and classification of edema
diff b/w renal and cardiac edema
sequences of events leading to cardiac and renal edema
diff b/w hyperemia and congestion
chronic venous congestion of lungs
diff b/w arterial and venous thrombus
types of emboli
pulmonary embolism
fat emboli
amniotic fluid embolism
different types of shock
stages of shock

1 star
diff b/w antemortem and postmortem clot
caisson's disease
renal infarct
fig-R-119,4.10-124,4.5-120,4.8-122

diseases of immunity
3 stars
type 1 hypersensitivity reaction
types of hypersensitivity reactions
type 2 hypersensitivity reaction
type 3 hypersensitivity reaction
type 4 hypersensitivity reaction
diff b/w acute and chronic rejection
graft vs host reaction
pathogenesis of AIDS+ oppurtunistic cancers in AIDS:- stages of HIV infection
pathogenesis of SLE
HIV:- lab d
diff b/w primary and secondary amyloidosis
morphology of SLE/classification of lupus nephritis

2 stars
diff b/w T and B cells
NK cells
transplant rejection
renal pathology in acute graft rejection
central and peripheral tolerance
mechanism of autoimmune disease
amyloid:- pathogenesis/types
primary amyloidosis
stains for amyloid
kidney in amyloidosis
indirect immuofluroscence in SLE

1 star
types of T cells
lepromin reaction
def of idiotype,allotype,isotype
diff b/w cytotoxic and helper t cells
diff b/w Th1 and Th2
role of HLA in disease
fig-6.14,6.15,6.16,6.21,6.41-R

neoplasia
3 stars
diff b/w benign and malignant tumors
diff b/w antioncogene and protooncogene
RB gene
P53 gene
mechanism of invasion and metastasis of malignant tumor
HPV carcinogenesis
EBV carcinogenesis
paraneoplastic syndromes

2 stars
diff b/w anaplasia and dysplasia
pathways of tumor spread
oncogenes
telomeres
chemical carcinogens and carcinogenesis
HTLV1 infection
cancer cachexia
FNAC
pap smear
flow cytometry
tumor markers

1 star
diff b/w metaplasia and dysplasia
diff b/w carcinoma and sarcoma
diff b/w hyperplasia and hypertrophy
cancer related genes
burkitt lymphoma genetic changes
oncogenic DNA and RNA virus
diff b/w DNA and RNA virus
methods to diagnose ca
histological method
alpha fetoproteins
carcinoembryonic antigen
carcinoma in situ

1/2 star
diff b/w hamartoma and neoplasia
gene amplification

genetic disorders
2 stars
fluroscence in situ hybridisation
down's syndrome
klinefelter syndrome
turner's syndrome
gaucher disease
mitochondrial inheritance

1 star
barr body
hermaphroditism
tay sachs
Neimann pick

1/2 star
glycogen storage disorder

infectious diseases,environmental and nutritional pathology


diff b/w tubercular and lepromatous leprosy
acute radiation syndrome/ radiation carcinogenesis
diff b/w kwashiorkar and marasmus
eye changes in vitamin A / vitamin A deficiency
predisposing factors for rickets and osteomalacia
bone changes in rickets / diff b/w scurvy and rickets
diet and cancer

diseases of infancy and childhood


neonatal respiratory distress syndrome
foetal hydrops
erythroblastosis foetalis
neuroblastoma
nephroblastoma/wilm's tumor

disorders of red blood cell


4 stars
sickle celled anemia- molecular changes and pathophysiology, factors affecting sickling,clinical features,lab d
thalassemia:- and features, diff b/w major,intermediate and minor
thalassemia:-pathogenesis
thalassemia:- lab d
thalassemia:- types
megaloblastic anemia:- causes,pathogenesis,lab d,pernicious anemia
iron deficiency anemia
blood transfusion reactions/acute transfusion reactions

3 stars
classify anemia according to etiology
lab d of hemolytic anemia
diff b/w extravascular vs intravascular hemolysis
pathology of hemolysis
pathology of hereditary spherocytosis
lab d of hereditary spherocytosis
G6PD
lab d of G6PD
paroxysomal nocturnal haemoglobinuria
autoimmune hemolytic anemia
sideroblastic anemia
anemia of chronic disease
aplastic anemia
blood component therapy

2 stars
classify anemia according to morphology
clinical signs and symptoms of anemia
causes of intravascular hemolysis
causes of extravascular hemolysis
coomb's test/antiglobulin test
causes of microcytic hypochromic anemia
causes of normochromic,normocytic anemia
red cell distribution width
erythrocyte sedimentation rate
diff b/w ABO and Rh blood grouping
bombay blood group
indications of bone marrow aspirate
polycythemia vera

1 star
hematopoiesis
classify hemolytic anemia acc to extrinsic and intrinsic causes
morphological abnormalities of RBCs in different types of anemia
haemoglobin
schilling test
vitamin B12
diff b/w megaloblast and normoblast
iron metabolism
diff b/w iron deficiency anemia and beta thalessemia
reticulocyte count
various systems of blood grouping
lab anticoagulants
complications of plasmodium falciparum malaria

bleeding disorders
3 stars
causes of thrombocytopenia
idiopathic thrombocytopenic purpura+ lab d
diff b/w acute and chronic thrombocytopenic purpura
von willebrand disease
haemophilia A
diff b/w heamophilia A and von willebrand disease
disseminated intravascular coagulation+ lab d
diff b/w bleeding in platelet and coagulative disorder

2 stars
bleeding time
clotting time
thrombin time
prothrombin time
partial thromboplastin time
functional defects of platelets

1 star
mechanism of hemostasis

disorders of white blood cells


3 stars
diff b/w lymphoblast and myeloblast
ALL,prognostic factors,FAB classification/cytochemistry
diff b/w ALL And AML
CLL
burkitt lymphoma
multiple myeloma:- enumerate all plasma cell neoplasms
hodgkin disease
AML,prognosis,FAB and WHO classification/cytochemistry
diff b/w CML and leukemoid reaction
diff b/w CML and CLL
lab D of CML
diff b/w hodgkin and non hodgkin lymphoma

2 stars
pancytopenia
etiopathogenesis and clinical features of leukemia
reed sternberg cells
philadelphia chromosomes
leukemoid reaction
causes of splenomegaly

1 star
classify leukemia
causes of lymphadenopathy
leucocyte alkaline phosphate
infectious mononucleosis
diff b/w CML and myeloproliferative disorder

heart and blood vessels


3 stars
atheromatous plaque
takayasu arteritis
polyarteritis nodosa
wegner's granulomatosis
buerger's disease
MI,complications,types of MI--> robbins
lab d of MI
infective endocarditis
acute rheumatic disease
diff b/w vegetations of LSE,NBTE,IE,RHD
diff b/w cardiomyopathy
diff b/w pericarditis
diff b/w heart failure

2 stars
diff b/w fatty streak and atheroma
types of vasculitis based on vessel size, type of inflammation
aneurysm of aorta
diff b/w types of angina
diff b/w acute and subacute endocarditis
diff b/w transmural and subendocardial infarct

1 star
AHA classification of atheromatous plaque
raynaud's phenomenon
diff b/w syphilitic and aortic aneurysm

lung
3 stars
emphysema
bronchial asthma
pneumonia:- pathogenesis, stages in lobar pneumonia,complications
diff b/w emphysema and bronchitis
diff b/w lobar and brochiopneumonia
TB lung
carcinoma lung:- classification and etiology:- pathogenesis,morphology and lab d
diff b/w squamous cell carcinoma and adenocarcinoma
diff b/w obstructive and restrictive lung disease

2 stars
atelectasis
diff b/w centriacinar and panacinar emphysema
primary atypical pneumonia
bronchiectasis
lung abscess
diff b/w primary and secondary TB
coal worker pneumoconiosis
silicosis
asbestosis
paraneoplastic syndromes
bronchial carcinoids
ARDS
Gohn complex/primary complex/ghon focus
diff b/w bronchiectasis and emphysema

1 star
definition of COPD
diff b/w TB and sarcoidosis
lab d of brochiogenic carcinoma:- classification and pathogenesis
indications of brochioalveolar lavage
causes of hemoptysis

gastrointerstinal tract
3 stars
role of H pylori in chronic gastritis
peptic ulcer
diff b/w benign and malignant ulcer
gastric carcinoma :- pathogenesis
crohn's disease
ulcerative colitis
types of polyps
colorectal cancer
diff b/w ulcerative colitis and crohn's disease
pathogenesis of ulcerative colitis

2 stars
barett oesophagus
carcinoma oesophagus
diff b/w duodenal ulcer and peptic ulcer
classify tumors of the stomach
diff b/w amoebic colitis and ulcerative colitis/amoebic colitis
diff b/w TB ulcer and typhoid ulcer
TB interstine
diff b/w tubular and villous adenoma
diff b/w leucoplakia and erythroplakia

1 star
pleomorphic adenoma
achalsia cardia
chronic gastritis:- definition,etiology,organism and virulence factors
zolingher ehlison syndrome
malabsorption syndrome
diff b/w celiac sprue and tropical sprue
ulceroinflammatory diseases of interstine
precancerous lesion of GIT
villous adenoma of small interstine and colon
carcinoid tumor of GIT
carcinoid syndrome
causes of melena
acute appendicitis
carcinoma appendix
ulcerative lesions of the small interstine

1/2 star
warthin tumor
meckel's divertaculum

liver and biliary duct


3 stars
prehepatic,hepatic and post hepatic jaundice
all types of hepatitis virus
lab d of hepatitis B and complications of hep B+ lab d of HCV
acute hepatitis and chronic hepatitis
diff b/w primary biliary cirrhosis and primary sclerosing cholangitis
gallbladder stone

2 stars
diff b/w alcoholic and biliary cirhhosis
hereditary hyperbilirubinemia
portal hypertension
diff b/w hepatitis A and B
hepatitis D
cirrhosis of liver
fatty liver
complications of alcoholic cirrhosis
diff b/w amoebic and pyogenic liver abscess
hepatocellular carcinoma

1 star
liver function tests
mechanism of ascites in cirrhosis
chronic active hepatitis
hepatitis C
hepatitis E
piecemeal necrosis
mallory bodies
hemachromatosis
alpha 1 antitrypsin
indian childhood cirrhosis
nutmeg liver

pancreas
2 stars
acute pancreatitis
chronic pancreatitis
difference b/w type 1 and type 2 DM
pathogenesis of type 1 DM

1 star
classify diabetes mellitus
lab d of diabetes mellitus
glucose tolerance test
complications of DM
advanced glycation end products
ketoacidosis

urinary system
3 stars
diff b/w acute and chronic renal failure:- lab d
diff b/w nephritic and nephrotic syndrome:- causes/causes of swelling in the body
IgA nephropathy:- minimal change glomerulonephritis/post streptococcal GN, membranous nephropathy
diabetic nephropathy:- kimmelstein wilson syndrome
urolithiasis
renal cell carcinoma
wilm's tumor

2 stars
pathogenesis of chronic kidney disease
diff b/w adult and childhood polycystic kidney disease
pathogensis of glomerulonephritis
rapidly progressive glomerulonephritis
diff b/w chronic glomerulonephritis and chronic pyelonephritis
diff b/w acute and chronic pyelonephritis
diff b/w ischemic and nephrotoxic ATN
diff b/w benign and malignant nephrosclerosis
diff b/w acute and chronic glomerulonephritis

1 star
renal function tests
diff b/w membranous nephropathy and minimal change disease
complications of chronic glomerulonephritis
urinary casts
diff b/w renal cell carcinoma and wilm's tumor
causes of hematuria
,polyuria,enlarged kidney,contracted kidney,proteinuria,glycosuria
tumors of urinary bladder
transitional cell carcinoma
bence jones proteinuria

male genital system


2 stars
benign prostatic hypertrophy
morphology and diagnosis of prostate cancer:- etiopathogenesis,precursor lesions
classify testicular tumors,etiology,clinical features
seminoma
diff b/w seminoma and non seminoma testis
lab d of prostatic cancer
prostate specific antigen

1.5 stars
embryonal carcinoma
yolk sac tumor of males
teratoma of testes
choriocarcinoma

one star
testicular atrophy
morphology and precursor lesions of penile carcinoma

female genital tract


2 stars
diff b/w complete and partial mole
dysgerminoma
teratoma
choriocarcinoma
krukenberg tumor
pathogenesis of cervical carcinoma/carcinoma cervix
endometrial hyperplasia
cervical intraepithelial neoplasm / carcinoma cervix
endometriosis
endometrial carcinoma:- pathogenesis
leiomyoma uterus
classify ovarian tumors
diff b/w serous and mucinous ovarian tumor
diff b/w mature and immature teratoma
diff b/w choriocarcinoma and H mole

1 star
adenomyosis
hormone producing tumors of ovary
teratoma ovary
yolk sac tumor of ovary

breast
3 stars
fibroadenoma breast
etiopathogenesis of breast carcinoma:- R-table 23.2, fig 23.14
phyllodes tumor
classification of breast carcinoma,microscopic features of invasive duct carcinoma
invasive carcinoma of breast
prognostic factors for carcinoma breast,

2 stars
benign epithelial lesions of breast
fibrocystic changes of breast
proliferative breast disease without atypia
proliferative breast disease with atypia
medullary carcinoma breast
non invasive carcinoma of breast
paget's disease of breast

endocrine system
hashimoto's thyroiditis
cushing syndrome
multinodular goitre
medullary carcinoma thyroid
papillary carcinoma thyroid
pheochromocytoma

skin
basal cell carcinoma

bones and joints


osteosarcoma
ewing sarcoma
rheumatoid arthritis
giant cell tumor of bone
pathogenesis of acute ostemyelitis

central nervous system and eye


meningioma
retinoblastoma
astrocytoma
diff b/w tubercular meningitis and pyogenic meningitis
glioblastoma multiforme

Created by
Gargi Aditi Mishra

(The maker of the word document is not responsible for any material contained within,
any failure to pass should not be attributed to the maker’s fault at all’ this document was
created during moments when the maker was feeling abnormally great about medical
school, which anyone attending it would agree is not normal or sane’)
previous yeMAMC sentLH sentup UC sentup 23

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