demand and supply Describe the Cardiovascular changes during exercise Myocardial Oxygen Demand
Directly related to amount of tension developed by
ventricles During exercise the cardiac output is increased 4 to 5 times in normal individual whereas increases 6 to 7 times in trained athlete It is determined by: Heart rate Preload Afterload Contractility Heart Rate
High Heart Rate:
More oxygen consumed at the tissue level Less oxygen rich blood delivered at the tissue level (less time for ventricular filling) Preload
Degree of Ventricular stretch at end Diastole
Determined by the volume of blood in the ventricle at end diastole With increased Preload in ventricular wall stress
in myocardial oxygen consumption
Afterload
The load against which the heart must
contract to eject blood into the aorta When afterload is high in ventricular wall stress in myocardial oxygen consumption Contractility
Strength of myocardial muscle fiber shortening
during systole Influenced by preload Greater muscle fiber stretch Greater recoil
When contractility is high
in wall stress in myocardial oxygen consumption Myocardial Oxygen Supply
Coronary Artery Anatomy
Diastolic Pressure Diastolic Time Oxygen Extraction Hemoglobin
PaO2 Coronary Artery Anatomy Diastolic Pressure and Time
The myocardium receives its blood during diastole
Diastolic pressure Blood Flow
Diastolic pressure Blood Flow
Diastolic time determines the time of coronary
blood filling Diastolic time Blood Flow Diastolic time Blood Flow Fast heart rate means less time for coronary blood filling Oxygen Extraction
Oxygen is transported through blood in two
ways Combined with hemoglobin Dissolved in blood Cardiovascular changes during exercise References
Guyton and Hall textbook of medical physiology,
12th edition Linda S. Costanzo, Physiology, 5th edition THANK YOU