Clinical clase

Divina Luz Mtz P.

ANEMIA APLÁSTICA
1. Background
A 32-year-old woman, who underwent mitral
valve surgery a year ago, consulted the doctor
for presenting progressive asthenia for 3
months, which has worsened in the last days.
Describes the appearance of spontaneous
bruising in the lower extremities.
There is no epistaxis, gingivorrhagia or
hematuria.
In recent months it has been treated with
several drugs: paracetamol, chlorothiazide,
indomethacin and digoxin.
2. Physical examination
• Good general condition Intense
mucocutaneous pallor. Head, mouth, pharynx
and neck
3. Laboratory
Hemogram
• Red blood cells: 2,400,000 / μ L
• Hematocrit: 20%
• Hemoglobin: 6.8 g / Dl
• VCM: 83.3 f
• Ictérico:<5 U
• Leukocytes: 2,100 / μ L
• Platelets: 25,000 / Μ l
4. Diagnosis
Anemia aplástica
5. Treatment
Transfusion of red blood cells and platelets.
Treatment with oral cyclosporine A begins.
6. Evolution
The bone marrow responds with an increase of
all the hematological series; the dose of the
immunosuppressant is decreased