INVESTIGATION OF THYROID GLAND DISEASE

PURPOSE OF TSH TEST

A thyrotropin hormone blood test (TSH) is used

to check if there is a problem with the thyroid
gland. TSH is generated when the hypothalamus
releases a substance called thyroberuline or
thyrotropin releasing hormone (TRH). Tiroliberin
will then trigger the pituitary gland to release
TSH. Normal levels of TSH are 0.25 - 5 μlU / mL
(microliter unit per milliliter). Low levels of TSHs
show hyperthyroidism, high levels of TSH
indicate hypothyroidism.
  Tracking the underactive
causes of the thyroid gland
(hypothyroidism). TSH levels
can help determine whether
hypothyroidism is caused by a
troubled thyroid gland or
because of other causes (eg
problems with the pituitary
BENEFITS gland or hypothalamus)
 Magnetic thyroid gland is
OF TSH TEST less active in the newborn
(congenital hypothyroidism)
 And some other reasons;
Diagnosing disorders of
thyroid function and
determining thyroid status
(hypothyroid, eutyroid, or
hyperthyroid)
 CLASSIFICATION OF TSH TEST
 Test to check thyroid function
1. T4 (serum thyroxine)
2. FT4
3. FT3
4. T3 (Tri-iodotironone serum)
 CLASSIFICATION OF TSH TEST

Tests to show the cause of impaired thyroid

function
1. Antibodies of Tiroglobulin (anti Tg)
2. Thyroid stimulating antibody
3. Microsomal antibodies
INTERPRESTATION OF TSH TEST

 High TSH Test Results

1. High TSH levels can be caused by underactive
thyroid gland (hypothyroidism). Hashimoto
thyroiditis is the most common cause of primary
hypothyroidism.
2. Tumors in the pituitary gland that produce too
much TSH.
3. Supplements consumed are not enough to cure
the underactive thyroid gland.
 Low TSH Test Results
1. Low levels of TSH can be caused by
overactive thyroid gland
(hyperthyroidism).
2. Damage to the pituitary gland that
prevents the gland to produce TSH (a
condition called secondary
hypothyroidism).
3. Too many doses to cure the
underactive thyroid gland.
4. Pregnancy in the first trimester.