Introductory

Biochemistry
Bioch 200
Course Outline and Objectives
 Biochemistry 200
Introductory Biochemistry
Section A3

TR 12:30-1:50 am
Telus 150

Dr. Jonathan Parrish

Source: http://xkcd.com
How to contact
your instructor
Dr. Jonathan Parrish
Department of Biochemistry
Room 5-79 MSB
jparrish@ualberta.ca
780-492-2866

Office Hours:
Wednesday 10:00am-12:00noon
Other Contacts
Dr. A. Wright
Biochemistry 200 Course Coordinator
5-81A Medical Sciences Building
awright@ualberta.ca; 492-8065

Ms. Shannon Swan

Biochemistry Student Services
5-81 Medical Sciences Building
shannon.swan@ualberta.ca; 492-5006
 Prerequisites
CHEM 101: Introductory University Chemistry I
CHEM 164 or 261: Organic Chemistry I

Check your registration, contact Shannon Swan if you have

concerns regarding your registration status.

The add/withdraw deadline for Winter term is September 21!

Course Content
1. Introduction

2. Biomolecules

3. Nucleotides and Nucleic Acids

4. Protein Structure and Function

5. Enzymes

6. Biological Membranes

7. Introduction to Metabolism

8. Glucose Metabolism
BIOCH 200: Course Objectives
 A one-term overview of the scope of
biochemistry.
 An introduction to the subject’s extensive
terminology.
 Emphasis on relevance to other fields (medicine,
nutrition, athletic performance).
 A foundation for further study in diverse subjects
(medicine, pharmacy/pharmacology, kinesiology,
nutrition, agriculture).
Who takes Bioch 200?
Who wants to take Bioch 200?
Support Materials
 Textbook “Essential Biochemistry”
 by Charlotte W. Pratt & Kathleen Cornely

 Practice Questions
 Recommended from the textbook
 Problem Sets
 Posted on WebCT
 Exam Questions
 Posted on WebCT

 Learning Objectives
 Posted on WebCT and in PowerPoint lectures
iClickers
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participation will be evaluated.
iClicker Assessment
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 3% if participate 51-75%
 5% if participate >75%
 Register your iclicker
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 First Name:
Last Name:
Student ID: User ID for eClass
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 Register by September 14th 2010
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same directions as if it were new.
 If the barcode has faded please bring your iClicker to me after class or to
Shannon in Rm 5-81 MSB.
Brainspan Game System
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 Practice Exam Questions

 YOU MUST change your alias (Starts as

userid)
Exam Schedule: BIOCH 200
 Midterm I – October 7th
 20%

 Midterm II – November 10th

 20%

 Final Exam – December 22nd

 55% (Cumulative)
 Consolidated exam
 Check the University exam schedule when it is posted.
Introductory Biochemistry
eClass
www.ualberta.ca/ELEARNING/

www.ualberta.ca/help
Call the Help Desk at 492-9400
helpdesk@ualberta.ca
Regulations Pertaining to
Deferred Examinations
 Do not miss exams.
 Medical excuse required.
 See Dr. Wright for permission to write
deferred exams.
 All deferred midterm examinations will
occur on December 9th.
 Deferred exams are short answer, not
multiple choice.
How to do well in this course
 Attend class.
 Review learning objectives and make sure
you can meet them all.
 Do the practice questions.
 Read the text and do the recommended
exercises.
Study!
 http://www.youtube.com/watch?v=2ArIj236UHs
Fundamentals of
Biochemistry
1. Introduction
What is Biochemistry?
What is Biochemistry?

 The scientific discipline that seeks to explain life at

the molecular level.

 A means for determining how organisms “work”

using the tools and terminology of chemistry.

 A practical science with wide-ranging applications in

a range of life science subjects, in treatment of
diseases, and in industry.
Levels of Organization in Organisms
Fundamentals of
Biochemistry
1. Introduction
Biomolecules
Elements in Biological Systems
Biomolecules

simple molecules H2O, CO2, NH3, O2, N2

building blocks amino acids, carbohydrates, nucleotides, lipids

polymers proteins, polysaccharides, nucleic acids

supra-molecular assemblies ribosomes, chromatin, membranes, etc.

organelles

cells

tissues, organs
The Four Major Classes of Biomolecule

amino acids

carbohydrates

lipids
nucleotides
Representing Biomolecules
Functional Groups and Linkages
Table 1.1
Table 1.1
Biopolymers
Biopolymers
Functions of Biopolymers

Biopolymer Encode Metabolic Store Cellular

Information Reactions Energy Structures
Proteins No Yes Somewhat Yes

Nucleic Acids Yes No No No

Polysaccharides Somewhat No Yes Yes

 Introductory
Biochemistry
1. Introduction
Water
Water
Water
Van der Waal’s Interactions
Bond Strength in Biological Molecules
The Electronegativity of Atoms
Groups That Can Make H Bonds
Solubility in Water: Hydrophilic Interactions
The Hydrophobic Effect
The Hydrophobic Effect
Amphiphilic molecules experience hydrophilic
interactions and the hydrophobic effect.
Amphiphilic molecules experience hydrophilic
interactions and the hydrophobic effect.