Scribd Logo
Upload

Welcome to Scribd!

  • Ácidos Carboxílicos - Parte - 2

    Uploaded by

    victor garcia vmg
    5 views8 pages
    The document discusses nucleophilic addition-elimination reactions of carboxylic acids. It explains that the reaction depends on whether the incoming nucleophile or the base in the reactant is a stronger or weaker base. If the incoming nucleophile is stronger, a new product will form. If it is weaker, the reactants will reform. If the two bases have similar basicities, a mixture of reactants and products results. It also notes that carboxylic acid derivatives can only be converted into less reactive derivatives.

    Original Description:

    Original Title

    ÁCIDOS CARBOXÍLICOS_PARTE_2.pptx

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    The document discusses nucleophilic addition-elimination reactions of carboxylic acids. It explains that the reaction depends on whether the incoming nucleophile or the base in the reactant is a stronger or weaker base. If the incoming nucleophile is stronger, a new product will form. If it is weaker, the reactants will reform. If the two bases have similar basicities, a mixture of reactants and products results. It also notes that carboxylic acid derivatives can only be converted into less reactive derivatives.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    5 views8 pages

    Ácidos Carboxílicos - Parte - 2

    Uploaded by

    victor garcia vmg
    The document discusses nucleophilic addition-elimination reactions of carboxylic acids. It explains that the reaction depends on whether the incoming nucleophile or the base in the reactant is a stronger or weaker base. If the incoming nucleophile is stronger, a new product will form. If it is weaker, the reactants will reform. If the two bases have similar basicities, a mixture of reactants and products results. It also notes that carboxylic acid derivatives can only be converted into less reactive derivatives.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 8

    ÁCIDOS CARBOXÍLICOS

    PARTE 2
    The Carbonyl Carbon is an Electrophile
    A Nucleophilic Addition–Elimination Reaction
    If the Incoming Nucleophile (Z) is a Stronger Base
    Than the Base in the Reactant (Y)

    The weakest base is eliminated from the tetrahedral intermediate.

    If the incoming nucleophile (Z) is a stronger base


    than the base in the reactant (Y),
    a new product will be formed.
    If the Incoming Nucleophile (Z) is a Weaker Base
    Than the Base in the Reactant (Y)

    The weakest base is eliminated from the tetrahedral intermediate.

    If the incoming nucleophile (Z) is a weaker base


    than the base in the reactant (Y),
    the reactants will be reformed.
    If the Two Groups Have Similar Basicities

    A mixture of reactants and products is obtained.


    The Relative Reactivities Depend on the Basicity of the
    Substituent Attached to the Leaving Group
    A Carboxylic Acid Derivative Can Be Converted
    Only into a Less Reactive Carboxylic Acid Derivative

    You might also like