Venous thromboembolism encompasses deep vein thrombosis and pulmonary embolism, which can cause death or disability. It is caused by Virchow's triad of endothelial injury, stasis, and hypercoagulability. Major risk factors include trauma, immobilization, and hypercoagulable states. Symptoms vary but include pain or swelling in the legs. Diagnosis involves clinical assessment, imaging tests, and D-dimer levels. Prevention focuses on early mobilization and mechanical devices, while treatment involves anticoagulation drugs.
Venous thromboembolism encompasses deep vein thrombosis and pulmonary embolism, which can cause death or disability. It is caused by Virchow's triad of endothelial injury, stasis, and hypercoagulability. Major risk factors include trauma, immobilization, and hypercoagulable states. Symptoms vary but include pain or swelling in the legs. Diagnosis involves clinical assessment, imaging tests, and D-dimer levels. Prevention focuses on early mobilization and mechanical devices, while treatment involves anticoagulation drugs.
Venous thromboembolism encompasses deep vein thrombosis and pulmonary embolism, which can cause death or disability. It is caused by Virchow's triad of endothelial injury, stasis, and hypercoagulability. Major risk factors include trauma, immobilization, and hypercoagulable states. Symptoms vary but include pain or swelling in the legs. Diagnosis involves clinical assessment, imaging tests, and D-dimer levels. Prevention focuses on early mobilization and mechanical devices, while treatment involves anticoagulation drugs.
(DVT) and Pulmonary Embolism (PE), and causes cardiovascular death and disability • VIRCHOW’S TRIAD – Endothelial injury – Stasis – Hypercoagulability PATHOPHYSIOLOGY RISK FACTORS • Trauma has been identified as one of the strongest risk factors leading to thromboembolism – Head injury – Spinal cord injury – Lower-extremity fracture – Pelvic fracture – Major surgical procedure • Patients who are subject to hypercoagulable state – Immobile – Ventilator-dependent COMMON SYMPTOMS CLINICAL LIKELIHOOD ASSESSMENT CLINICAL LIKELIHOOD ASSESSMENT DIAGNOSIS DIAGNOSIS CHEMICAL PROPHYLAXIS NON-PHARMACOLOGIC PROPHYLAXIS • 1st line prevention: – Promoting mobilization to the extent permitted by the injury raises cardiac output augments venous flow through muscle compression • Mechanical Devices: – Graduated compressive stockings – Pneumatic pumps TREATMENT DVT •LMWH, fondaparinux, Unfractionated, intravenous heparin