SL - Parasitology

Maharani Kartika

130110180136
 I : 10 YO, Male
Case Analysis
E : S. haematobium Infection
Rf : Swim at endemic area
CC : Pain during urination
x
Urinary Tract Infection Urinary Tract Obstruction
x x
HT SE

1. Accompanied by 1. Stool Exam : S.

fever, muscle aching, haematobium (+)
itchiness at his back
2. High-level of
2. An immigrant Eosinophil
from Sudan

3. He likes to swim

D : Urinary Tract S. haematobium Infection

 Agent of Infection : Schistosoma haematobium

1. History

2. Habitat

3. Morphology :

• Adult Worms

• Eggs
Life Cycle of
Agent
 Signs and Symptoms
Acute Chronic :

(Katayama Fever) :

1. Fever 1. Abdominal pain

2. Ascites
2. Abdominal pain (liver/spleen area)
3. Bloody diarrhea
3. Bloody diarrhea 4. Hematuria
5. Pain during urination
4. Cough
6. Shortness of breath & cough
5. Malaise 7. Weakness

6. Rash 8. Chest pain and palpitations

9. Seizures
7. Body Aches
 Lab Finding
1. Urine microscopy : S. haematobium eggs (+)

2. Bladder mucosa/rectal biopsy : S. haematobium eggs (+)

3. Serology : S. haematobium antigen and specific

antibody (+)

4. X-Ray : Bladder/urethral calcification

5. High-level of eosinophilia
Pathogenesis
 Prevention
• Eradication of the intermediate molluscan hosts by
using molluscicides.

• Prevention of environmental pollution with urine

and feces.

• Effective treatment of infected persons.

• Avoid swimming, bathing and washing in infected

water.
 Treatment
Praziquantel Metriphonate

(40 – 60 mg/kg, divided dose per day) (7.5 mg/kg weekly, for 3 weeks,
alternative drug of choice)

MOA : MOA :

Causing severe spasms and paralysis of Requires further study for specific

worm’s muscles  Vacuolization & MOA as an antihelminthic drugs

disintegration of schistosome tegument