ANALISIS SEDIAAN OBAT

Bina Lohita Sari

Prodi Farmasi FMIPA UNPAK
2019
 OKSIDASI

• Oxidation at carbon centre:

• at aromatic ring, olefinic centre, and
aliphatic groups. Important drugs
undergoing metabolism by this reaction
include acetanilide (analgesic),
phenylbutazone (analgesic), valproic
acid (antiepileptic), carbamazepine
(antiepileptic), and minoxidil
(antihypertensive)
TRANSISI ELEKTRONIK
Oxidation at carbon-heteroatom systems: This involves reaction on C–N, C–S
and C–O systems. The oxidation reactions on C–N systems comprise of N-
dealkylation, oxidative deamination, formation of N-oxide, or N-hydroxylation
REDUKSI
HIDROLISIS
 FASA II

glucuronic acid, glutathione, sulphate, glycine

 LATIHAN SOAL

Analisis Tetrahidrocannabinol (THC)