PENTOSE PHOSPHATE PATHWAY,GALACTOSE

METABOLISM &GLYCOLYSIS

ASSIGNMENT#02

Submitted To : Dr.Aqsa
Submitted By: Mahnoor Abbas
Roll No:19011560-082
Section :BIOTECH (B)

DEPARTMENT OF BIOCHEMISTRY AND BIOTECHNOLOGY

Contents
• 01.Galactose metabolism pathway
• 02.Glycolysis pathway
• 03.Pentose phosphate pathway
• 04.Linkage between them
 GLACTOSE
Glucose-1-phosphate
ATP
UTP Glactokinase
UDP-Glc-
Pyrophos. ADP
PPi

Galactose-1-phosphate
UDP-Glucose

UDP-Glc:Gal-1-P
UDP-Gal uridylyltransferase
epimerase

UDP-Galactose
Glucose-1-phosphate

phosphoglucomutas
e
01.GLACTOSE
METABOLISAM
Glucose-6-phosphate
 Glucose(GLU)

02.GLYCOLISIS ATP
Hexokinase
PATHWAY ADP

Glucose-6-phosphate(G6P)

Fructose-6-6phosphate(F6P)

Pyruvate(PVR) ATP
2ADP
ADP
2ATP Fructose-1,6-bisphosphate(F6P)

Phosphoenolpyruvate(PEP)

Dihydroxyacetone
Phosphate(DHAP)

2-phosphoglycerate(2-PG)

Glyceraldehyde-3-phosphate(GA3P)

3-phosphoglycerate(3-PG) 2ATP
2ADP

1,3-bisphosphoglycerate(1,3BPG)
 03.PENTOSE
PHOSPHATE PATHWAY
Glucose-6-phosphate
NADP+

Glucose-6-phosphate
dehydrogenase

NADPH

Glucono-1,5-lactone-6P

6-phosphogluconate
Glycolysis
NADP+

6-phosphogluconate
Dehydrogenase

Fructose-6- NADPH
phosphate
Ribulose-5-phosphate

Ribulose-5-phosphate Ribose-5-phosphate
3-Epimerase isomerase

Ribose-5-
Xylose-5- phosphate
phosphate
04.LINKAGE OF GLYCOLISIS PATHWAY
PATHWAYS Glucose
GLACTOSE
METABOLISM
G6PD PATHWAY
Ribose-5- Riulose-5-phosphate Glucose-6-phosphate
phosphate UTP
GPI Glucose-1-P
ADP PPi
Fructose-6-phosphate

TLKT/TKTL2 ATP
UDP-
Xylose-5-phosphate Glucose+
Glucose (Glucose)n
Glyseraldehyde-3-
phosphate
pi
Branching
(Glucose )
n+1
3-phosphoglycerate

PGAM1
PENTOSE PHOSPHATE
PAHTWAY
2-phosphoglycerate

Phospho-enol-pyruvate

PKM2
CYTOPLASM
pyruvate