Fat synthesis (storage) Amino acid synthesis Glycoconjugate Pentose phosphate pathway 2. Four pathways where G6P is the common molecule Glycolysis Gluconeogenesis Glycogenesis Pentose phosphate pathway 3. Citrate (6C) Isocitrate (6C) 4. Isocitrate (6C) ∝-ketogluturate (5C) 5. ∝-ketoglutarate (5C) Succinyl CoA (4C) 6. Succinyl CoA (4C) Succinate (4C) 7. Succinate (4C) Fumarate (4C) 8. Fumarate (4C) Malate (4C) 9. Malate (4C) Oxaloacetate (4C) 10. Oxaloacetate (4C) Citrate (6C) 11. Link reaction: enzyme Pyruvate dehydrogenase 12. Pentose Phosphate Pathway (PPP): products - NADPH - Pentose Phosphate - ATP 13. PPP: two main enzymes (in the nonoxidative - Transketolase reactions) - Transaldolase 14. NADPH: function Reducing agent to prevent oxidative species damage 15. Pentose phosphate: example Ribose 5' phosphate 16. Pentose phosphate: function Precursor for nucleotides 17. Intermediate for glucose entering PPP G6P 18. Outline synthesis of amino acids and fats from Glucose --> citrate (in mitochondria) --> transported out --> cleaved to form glucose acetyl group + oxaloacetate 19. Glucoconjugates (3) UDP-glucose UDP-glucuronate UDP-galactose 20. UDP-glucose: function Glycogen synthesis 21. Give examples of things that UDP- Glycoproteins glucuronate/galactose is used to make Proteoglycans Glycolipids Glucuronides (glucuronate)