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de los carbohidratos
El estudio de los carbohidratos debe
considerar
1. Central pathways of carbohydrate metabolism
Entner-Doudoroff o Cetogluconato
3. Structural rearrangements
1. EMP
2. Entner-Doudoroff
3. Pentosa fosfato
4. Fosfogluconato
5. Ciclo oxidativo de pentosa fosfato ?
Diferencias entre la glucólisis y la via de la
pentosa fosfato
Glycolysis generates NADH, which can be reoxidized by linkage to the
electron transport system, or under anaerobic conditions it can be used to
reduce an oxidized substrate, such as pyruvate, to lactate.
Diferencias entre la glucólisis y la via de la
pentosa fosfato
The pentose phosphate pathway generates NADPH, which is used primarily
for reducing power in biosynthetic reaction (e.g., the conversion of α-
ketoglutarate to glutamate or the incorporation of acetate into fatty acids)
and is not linked to the terminal respiratory system.
Operation of the TCA
cycle under
anaerobic
conditions.
GLUCONEOGENESIS
Growth of microorganisms on poor carbon sources,
(L-malate, succinate, acetate, or glycerol),
5. Phosphofructokinase (pfkA).
Phosphorylation of F-6-P to FBP using ATP.
16. Fructose-1,6-bisphosphatase. Removes
Pi from F-1,6-bisP to form F-6-P.
The third bypass reaction required for gluconeogenesis
involves dephosphorylation
of G-6-P