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Contricted pupil

What is miosis?

 Miosis is defined as a pupil size of 2 mm (a little over 1/16th inch) or smaller.


 Miosis is a symptom of something else and not a disease in itself.
 It can provide an important clue to your doctor in finding the underlying
cause.
 The size of your pupil is controlled by 2 counteracting muscles — the iris
dilator and the iris sphincter.
Causes of miosis

Diseases or conditions that can cause miosis


 cluster headaches
 Horner’s syndrome
 intracranial hemorrhage and brain stem stroke
 iris inflammation (iridocyclitis, uveitis)
 Lyme disease
 neurosyphilis
 multiple sclerosis (MS)
 Aphakia
Drugs and chemicals that can cause miosis

 PCP (angel dust or phencyclidine)


 Heroin, morphine and other opioids
 tobacco products and other nicotine-containing substances
 pilocarpine eye drops used to treat glaucoma
 cholinergic drugs used to stimulate the parasympathetic nervous
system, including acetylcholine, carbachol, and methacholine
 second-generation or atypical antipsychotics, including
risperidone, haloperidol, and olanzapine
 phenothiazine-type antipsychotics used to treat schizophrenia,
including prochlorperazine (Compazine, Compro), chlorpromazine
(Promapar, Thorazine), and fluphenazine (Permitil, Prolixin)
 organophosphates, found in many insecticides, herbicides, and
nerve agents
Age related miosis
 Newborns
 Old individuals- due to weakness of dialator muscles

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