DEFINISI, ETIOLOGI, No.

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KLASIFIKASI CKD
 DEFINISI
oChronic kidney disease (CKD) didefinisakan dengan adanya
keadaan dimana ginjal mengalami kerusakan atau estimasi laju
filtrasi glomerulus(estimated Glomerular Filtration rate(eGFR))
kurang dari 60 ml/menit/1,73 m2, dimana keadaan ini bertahan
selama 3 bulan atau lebih.
oCKD ini adalah keadaan dimana fungsi ginjal hilang secara
progresif yang pada akhirnya mengakibatkan dibutuhkannya
terapi renal replacement (Dialysis, atau Transplantasi)
 ETIOLOGI
The most common primary diseases causing CKD and ultimately end-stage renal disease (ESRD) are
as follows
 Diabetes mellitus type 2 (30% to 50%)
 Diabetes mellitus type 1 (3.9%)
 Hypertension (27.2%)
 Primary glomerulonephritis (8.2%)
 Chronic Tubulointerstitial nephritis (3.6%)
 Hereditary or cystic diseases (3.1%)
 Secondary glomerulonephritis or vasculitis (2.1%)
 Plasma cell dyscrasias or neoplasm (2.1)
 Sickle Cell Nephropathy (SCN) which accounts for less than 1% of ESRD patients in the United
States
 ETIOLOGI
 CKD may result from disease processes in any of all these categories: prerenal (decreased renal
perfusion pressure), intrinsic renal (pathology of the vessels, glomeruli, or tubules-interstitium), or
postrenal (obstructive).
 Prerenal Disease
 Intrinsic Renal Vascular Disease
 Intrinsic Glomerular Disease (Nephritic or Nephrotic)
 Intrinsic Tubular and Interstitial Disease
 Postrenal (Obstructive Nephropathy)
KLASIFIKASI
REFERENSI
https://kdigo.org/wp-content/uploads/2017/02/KDIGO_2012_CKD_GL.pdf
https://www.ncbi.nlm.nih.gov/books/NBK535404/#article-28357.r3
https://www.kidney.org/professionals/explore-your-knowledge/how-to-classify-ckd