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HOSTS (Vibrio
ages, environmental
(All(Poor
AGENT
Environment both
Cholera)
sexes)
factors
ETIOLOGICAL
FACTORS/AGENT
1. The Organism is a slightly curved rod
(comma-shaped), Gram negative and motile
with a polar flagellum.
2. The organism survives well at ordinary
temperatures ranging from 22-40°C.
3. They survive longer in refrigerated foods.
4. An enterotoxin, cholerapen, is elaborated
by a organism as it grows in the intestinal
tract.
CHOLERA
PATHOGNOMONIC SIGN
Rice water stools
INCUBATION PERIOD
The incubation period ranges from a few hours
to 5 days, usually one to three days.
PERIOD OF COMMUNICABILITY
The organisms are communicable during the
stool-positive stage, usually a few days after
recovery, however, occasionally may the
carrier have the organism for several months.
MODE OF TRANSMISSION
i) STAGE OF EVACUATION
The onset is abrupt with profuse
painless, watery diarrhoea followed
by vomiting. The patient may pass
as many as 40 stools in a day.
CLINICAL FEATURES
ii) STAGE OF COLLAPSE
• Sunken Eyes.
• Hollow checks.
• Scaphoid abdomen.
• Washer-man hand and feet.
• loss of elasticity of skin.
• Sub-normal temperature.
• Absent pulse.
• Low BP.
• Shallow and quick Respiration.
• Oliguria
CLINICAL FEATURES
iii) STAGE OF RECOVERY
If death does not occur the patient shows
signs of clinical improvement.
→ BP begins to raise, temperature returns to
normal and urine secretion is re established.
If anuria persists the patient may die renal
failure, severe cholera occurs in 5 to 10% of
cases.
LABORATORY DIAGNOSIS
i) Collection Stool
ii) Collection vomitus
iii) Water
iv) food samples
v) Transportation
vi) Direct examination
vii) Culture method.
CONTROL OF CHOLERA
2. NOTIFICATION
Educate the vulnerable group regarding the disease.
5. REHYDRATION THERAPY
Mortality rate have been brought down to less than by effective rehydration
therapy.
6. ADJUNCTS TO THERAPY
Antibiotics should be given as soon as vomiting has stopped which is usually
after 3-4 hours of oral rehydration
Eg. fluroquinolones, tetracycline, ampicillin.
CONTROL OF CHOLERA
7. SANITATION MEASURES
i) Water control
ii) Excreta disposal
iii) Food sanitation
iv) Disinfection.
NURSING MANAGEMENT