Professional Documents
Culture Documents
Smriti Poudel
Lecturer
1
Normal Breast
Breast profile
A ducts
B lobules
C dilated section of duct to hold milk
D nipple
E fat
F pectoralis major muscle
G chest wall/rib cage
Enlargement
A normal duct cells
B basement membrane (duct wall)
C lumen (center of duct)
2 © Mary K. Bryson
Illustration
Breast Cancer (BC)
Introduction:
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Contd…
4
Etiology and Risk Factors
• Etiology not known
Risk Factors
6
Ovarian and Hormonal Function (Contd.)
– Oophorectomy before a woman reaches menopause
lowers her risk of breast cancer by approximately
two thirds.
• Family History:
9
Risk Factors (Contd.)
10
Breast Cancer Risk Factors
that cannot be changed
Age
GENDER - All Reproductive
women are History
Family/Personal
at risk
History
Menstrual
Race History
Radiation
Genetic
Factors 11
Breast Cancer Risk Factors
that can be controlled
Obesity
All Not having
women
women are
are Family planning
Exercise children
at
at risk
risk
Breastfeeding
Breastfeeding
Birth Control
Birth Control
Hormone
Hormone Pills
Alcohol Replacement
Replacement
Therapy
Therapy 12
Protective Factors
• Regular, vigorous exercise
• Breastfeeding
13
Types of Breast Cancer
• Carcinoma in Situ (Noninvasive): ductal and lobular
• Invasive Carcinoma
– Infiltrating ductal carcinoma
– Infiltrating lobular carcinoma
• Medullary Carcinoma
• Mucinous Cancer
• Tubular Ductal Cancer
• Inflammatory Cancer
• Paget’s Disease: disease of the breast is a rare form of
breast cancer. Paget's disease of the breast starts on the
nipple and extends to the dark circle of skin (areola)
around the nipple. 14
Carcinoma in situ
• This disease is characterized by the proliferation of
malignant cells within the ducts and lobules,
without invasion into the surrounding tissue;
therefore, it is a noninvasive form of cancer and is
considered stage 0 breast cancer.
15
Ductal Carcinoma in situ (DCIS)
Ductal
cancer
cells
Normal
ductal
cell
16
Illustration © Mary K. Bryson
DCIS
17
Lobular Carcinoma in Situ
• LCIS is characterized by proliferation of cells
within the breast lobules.
18
• Historically, treatment was bilateral total
mastectomy, but LCIS is a marker of increased
risk for the development of an invasive cancer
(rather than an actual malignancy).
19
INVASIVE CARCINOMA
Infiltrating Ductal Carcinoma
• Infiltrating ductal carcinomas are the most common
histologic type of breast cancer and account for 75% of all
breast cancers.
21
• Infiltrating ductal and infiltrating lobular
carcinomas usually spread to bone, lung, liver,
or brain, whereas lobular carcinomas may
metastasize to meningeal surfaces or other
unusual sites.
22
Medullary Carcinoma
• Medullary carcinoma constitutes about 6% of
breast cancers and grows in a capsule inside a
duct.
23
Mucinous Cancer
• Mucinous cancer accounts for about 3% of
breast cancers.
24
Tubular Ductal Cancer
• Tubular ductal cancer accounts for only 2% of
cancers.
25
Invasive Ductal Carcinoma (IDC –
80% of breast cancer)
27
Invasive Lobular Carcinoma (ILC)
Lobular cancer
cells breaking
through the
wall
28
Illustration © Mary K. Bryson
Cancer Can also Invade Lymph or
Blood Vessels
Cancer cells
invade
lymph duct
Cancer cells
invade
blood vessel
29
Illustration © Mary K. Bryson
Inflammatory Carcinoma
• Inflammatory carcinoma is a rare type of breast
cancer (1% to 2%) with symptoms different from
those of other breast cancers.
30
• Often, edema and nipple retraction occur.
31
Staging of BC
Stage I:
Tumors are less
than 2 cm in
diameter and
confined to
breast.
32
Staging of BC
Stage II:
Tumors are less
than 5 cm, or
tumors are smaller
with mobile
axillary lymph
node involvement.
33
Stage IIIa:
Tumors are greater
than 5 cm, or
tumors are
accompanied by
enlarged axillary
lymph nodes fixed
to one another or to
adjacent tissue.
34
Stage IIIb:
More advancd
lesions with
satellite nodules,
fixation to the skin
or chest wall,
ulceration, edema,
or with supra-
clavicular or
intraclavicular
nodal involvement.
35
Stage IV:
All tumors with
distant
metastases.
36
Signs and Symptoms
Most common:
lump or
thickening in
breast. Often
painless
Change in color
Change in size or appearance
or
37
contours of of areola
breast
Signs and Symptoms
• A spontaneous clear or bloody discharge from nipple, often
associated with a breast lump
40
Mammography
• Two views are taken of each breast:
– a craniocaudal view
– a mediolateral oblique view
A baseline mammogram
should be obtained after
the age of 35 years
and by the age of 40.
41
Management
• Surgery
• Chemotherapy
• Radiation therapy
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43
Modified Radical Mastectomy
• Modified radical mastectomy is removal of the
entire breast tissue, along with axillary lymph
nodes.
44
45
Breast-Conserving Surgery
• Breast-conserving surgery consists of:
– lumpectomy,
– wide excision,
– partial or segmental mastectomy, or quadrantectomy
(resection of the involved breast quadrant)
– removal of the axillary nodes (axillary lymph node
dissection)for tumors with an invasive component,
followed by a course of radiation therapy to treat
residual, microscopic disease.
46
Contraindications
Breast-conservation treatment includes both
surgery and radiation.
• First or second trimester of pregnancy
• Prior radiation to the breast or chest region
• History of collagen vascular disease
• Large tumor-to-breast ratio
47
ROLE OF RADIOTHERAPY IN BREAST
CANCER
Breast conservation
Adjuvant radiotherapy
Palliative radiotherapy
48
ADJUVANT RADIOTHERAPY
Indications of Radiation therapy
Patients with 4 or more positive lymph nodes
Presence of extracapsular extension, positive or close
margins
T3 tumors with positive lymph nodes, medial quadrant
tumors
Any T4 tumors and pectoral fascia involvement
49
RADIATION THERAPY
• With breast-conserving surgery, a course of external-
beam radiation therapy usually follows excision of the
tumor mass to decrease the chance of local recurrence
and to eradicate any residual microscopic cancer cells.
51
Contd….
52
Hormonal Therapy
• Hormonal therapy may include surgery to
remove endocrine glands (eg, ovaries,
pituitary, or adrenal glands) with the goal of
suppressing hormone secretion.
53
Contd….
54
Prosthesis
• Women should be encouraged to wear the
prosthesis because it provides a sense of
psychological restoration and wholeness.
55
Contd….
56
POTENTIAL COMPLICATIONS
57
Lymphedema
58
Nursing Process
• Health history:
– Client response to diagnosis.
– Coping mechanism which is helpful to her
– Psychological and emotional support: does she
have and use?
– Partner, family members or friends to make
decision
– Most important areas of information she needs
– Client’s discomfort
59
Nursing Diagnosis
Preoperative
• Deficient knowledge about breast cancer and
treatment options
• Anxiety related to cancer diagnosis
• Fear related to specific treatments, body image
changes, or possible death
• Risk for ineffective coping (individual or family) related
to the diagnosis of breast cancer and related treatment
options
• Decisional conflict related to treatment options
60
Postoperative
• Acute pain related to surgical procedure
• Impaired skin integrity due to surgical incision
• Risk for infection related to surgical incision and
presence of surgical drain
• Disturbed body image related to loss or
alteration of the breast related to the surgical
procedure
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Contd….
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Contd…..
63
Goal
• Increased knowledge about the disease and its
treatment;
• Reduction of preoperative and postoperative fears,
anxiety, and emotional stress;
• Improvement of decision-making ability; pain
management;
• Maintenance of skin integrity;
• Improved self-concept;
• Improved sexual function; and
• The absence of complications.
64
Preoperative Nursing Interventions
1. EXPLAINING BREAST CANCER AND TREATMENT
OPTIONS
65
Contd….
66
REDUCING FEAR AND ANXIETY AND IMPROVING COPING
ABILITY
• Patients who have lost close relatives to breast cancer (or any
cancer) may have difficulty coping with the possible diagnosis of
breast cancer because memories of loss and death can emerge
during their own crisis.
• Fears and concerns are common and are discussed with the patient.
67
Contd….
• Discussion with a plastic surgeon about the various
options for reconstructive surgery can be a valuable
source of information and support.
68
PROMOTING DECISION-MAKING ABILITY
69
Postoperative Nursing Interventions
70
Contd….
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Contd…
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MAINTAINING SKIN INTEGRITY AND PREVENTING
INFECTION
• In the immediate postoperative period, the patient will
have a snug but not tight dressing or a surgical bra
packed with gauze over the surgical site and one or
more drainage tubes in place.
74
Contd…
75
Contd…
76
Contd….
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Contd….
78
PROMOTING POSITIVE BODY IMAGE
79
Contd…..
• Ideally, she will see the incision for the first time when
she is with the nurse or another health care provider
who is available for support.
80
PROMOTING POSITIVE ADJUSTMENT AND
COPING
• Ongoing assessment of the patient’s concerns.
82
PROMOTING PARTICIPATION IN CARE
83
Exercise: Wall hand climbing
1. Stand facing the wall with feet
apart and toes as close to the
wall as possible.
2. With elbows slightly bent, place
the palms of the hand on the
wall at shoulder level.
3. By flexing the fingers, work the
hands up the wall until arms are
fully extended.
4. Then reverse the process,
working the hands down to the
starting point.
84
Exercise: Rod or broomstick lifting
1. Grasp a rod with both hands,
held about feet apart.
2. Keeping the arms straight,
raise the rod over the head.
3. Bend elbows to lower the rod
behind the head.
4. Reverse maneuver, raising
the rod above the head, then
return to the starting position.
85
Exercise: Rope turning
88
IMPROVING SEXUAL FUNCTION
• Most breast surgery patients are physically allowed to
engage in sexual activity once discharged from the
hospital.
89
Contd….
90
Contd….
91
MONITORING AND MANAGING
POTENTIAL COMPLICATIONS
1. Lymphedema
• Lymphedema can occur any time after an axillary
lymph node dissection.
95
Management consists of:
• Arm elevation with the elbow above the shoulder
and the hand higher than the elbow, along with
specific exercises, such as hand pumps.
96
Hematoma Formation
97
Infection
• Infection follows breast surgery in about 1 in 100
patients.
98
Continuing Care
• Assess for incision and drainage system, physical and
psychological status, adequacy of pain management,
and adherence to the exercise plan.
99
Contd….
100
Contd….
101
RECONSTRUCTIVE SURGERY
• Women may undergo reconstruction immediately (at
the time of mastectomy) or delay it (6 months to 1
year after surgery)
102
Contraindications
• Metastasis, or
103
Contd….
104
REDUCTION MAMMOPLASTY
• Reduction mammoplasty is usually performed on
women who have breast hypertrophy (excessively
large breasts).
105
106
AUGMENTATION MAMMOPLASTY
107
Contd…..
111
RECONSTRUCTIVE PROCEDURES
AFTER MASTECTOMY
112
Tissue Expanders With Permanent Implants
• One method of reconstruction is the tissue expander
with permanent implant.
117
Tissue Transfer Procedures
• Another method of reconstruction is using the
patient’s own tissue and transferring it to the
mastectomy site.
118
Contd…..
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124
Nipple–Areola Reconstruction
• After the breast mound has been created and the site has
healed, some women choose to have a nipple–areola
reconstruction.
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THANK YOU
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