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D.Safaa D.Elsherbiny
Objectives
• List the trigeminal nerve nuclei and their
location
• Follow up the course of trigeminal nerve
from its point of central connections to
exit and down to its target areas.
• Describe the sensory and motor
components of the trigeminal nerve.
Trigeminal nerve
Type: mixed nerve formed of a large sensory root and a small motor root. The
largest cranial nerve
:Origin
Sensory root: arise from the trigeminal ganglion ( Gasserian , semilunar .1
.ganglion)
:a. The peripheral branches form the 3 divisions of the trigeminal nerve
.ophthalmic, maxillary and mandibular
b. The central branches form the sensory root of the trigeminal nerve.
.Motor root: from the motor nucleus in the pons. It joins the mandibular nerve .2
Fibers:
1. General somatic
afferent:
Carrying general
sensations from face.
2. Special visceral
efferent:
Supplying muscles
developed from the
1st pharyngeal
arch, (8
muscles).
Nuclei:
4 nuclei (motor and 3 sensory)
1. One motor nucleus: in the
lateral part of the pontine
tegmentum (mid pons).
2. Three sensory nuclei:
a. Mesencephalic nucleus: in
the midbrain, for proprioception
from the face.
b. Main sensory nucleus: in the
pons, for discriminative touch
from the face.
c. Spinal trigeminal nucleus: in
the medulla, for pain and
temperature sensations from the
face.
Trigeminal Nerve
Emerges from the middle
of the ventral surface of
the pons
Divisions:
1. Ophthalmic.
2. Maxillary.
3. Mandibular.
Axons of cells of
motor nucleus join
only the mandibular
division.
Pure Sensory
Pure Sensory
C2,3
Great
.auricular N
Mixed Nerve
Site:
Occupies a depression
in the middle cranial
fossa.
Importance: Contains
cell bodies:
1. Whose dendrites carry
sensations from the
face.
2. Whose axons form the
sensory root of
trigeminal nerve.
Ophthalmic nerve
(Pure Sensory)
Type: purely sensory nerve.
Origin: It arises from the trigeminal
ganglion.
Course:
It passes in the lateral wall of the
cavernous sinus and divides into 3
branches that enter the orbit through
the “superior orbital fissure”.
Branches:
1. Frontal: supplies skin of face &
scalp.
2. Lacrimal: supplies skin of face &
lacrimal gland.
3. Nasociliary: supplies skin of face,
nasal cavity & eyeball.
Maxillary nerve
(Pure Sensory)
Type: purely sensory nerve.
Origin: It arises from the trigeminal ganglion.
Course:
It passes in the lateral wall of the cavernous sinus → passes through foramen
rotundum → enters the pterygopalatine fossa → passes through the inferior
orbital fissue to continue as the infraorbital nerve → passes through the
infraorbital groove, infraorbital canal and the infraorbital foramen.
Maxillary nerve
Supplies the:
1. Upper teeth, gums &
maxillary air sinus:
(posterior, middle &
anterior superior
alveolar nerves).
2. Face:
(zygomaticofacial ,zygomatic
otemporal & infraorbital
nerves).
Branches
Maxillary nerve block (Dentists)
Mandibular nerve
(Mixed)
Type: mixed nerve.
Origin: It arises by two roots,
motor and sensory:
1. Motor root (small):
from the motor nucleus of the
trigeminal nerve in the pons.
2. Sensory root (large):
from the trigeminal ganglion.
Course:
The 2 roots pass through foramen
ovale → unite below foramen
ovale to form a short mandibular
nerve trunk → divides into
anterior and posterior divisions.
Mandibular nerve
• SENSORY BRANCHES:
1. Lingual:
General sensations from anterior 2/3
the of tongue.
2. Buccal: Face(cheek on upper jaw)
3. Auriculotemporal:
auricle, temple, parotid gland & TMJ.
4. Inferior alveolar:
Lower teeth, gums & face.
• MOTOR BRANCHES:
1.Four muscles of mastication:
Masseter, Temporalis, Medial And
Lateral Pterygoid.
2. Other 4:
Anterior belly of Digastric, Mylohyoid,
Tensor Palati and Tensor Tympani.
Clinical Anatomy
Paralysis of lateral
pterygoid muscles
causes the jaw to
deviate towards the
paralysed side on
opening the mouth as
a result of action of
normal muscle.
Trigeminal Neuralgia
• Compression, degeneration or
inflammation of the 5th cranial nerve
may result in a condition called
trigeminal neuralgia or tic douloureux.
• This condition is characterized by
recurring episodes of intense stabbing ,
excoriating pain radiating from the
angle of the jaw along a branches of
the trigeminal nerve.
• Usually involves maxillary &
mandibular nerves, rarely in the
ophthalmic division.
Trigeminal block
A trigeminal nerve block is
an injection of medication
e.g carbamazepine, that
helps relieve facial pain.
It’s used to treat:
1-Trigeminal neuralgia
2- Herpes zoster infection
(or “shingles”) affecting
the face
3- Other atypical facial
pain syndromes
Inferior alveolar block (Dentists)