PERIYAR UNIVERSITY, SALEM

.
FIRST DOCTORAL COMMITTEE MEETING
Date : 01- 03 - 2022

Research Scholar : Mr. A.RAJA, M.Sc., M.Phil.,

Dr.C.Chandrasekar, Dr. S.Prema Dr.J.K.Kanimozhi

Professor and Head i/c, Assistant Professor in Computer Assistant Professor
Department of Computer Applications, PG & Research Dept. of
1 Arulmigu Arthanareeswarar Arts and Computer Science
Science,
Periyar University, Science College, Sengunthar Arts & Science
Salem. Tiruchengode. College Tiruchengode.
 Title of the Research
“ CLONALG BASED ACCURATE
DETECTION OF ALZHEIMER’S
DISEASE THORUGH EEG SIGNAL ”
2
3 CONTENT
 Domain
 Aim & Objectives
 Proposed Architecture
 Introduction
 Problem Statement
 Proposed System
 Review of Literature
 Conclusion
 Reference
4 DOMAIN
Big Data

 Big Data is a term used to describe a collection of huge volume of data and yet growing exponentially
with time.

 Big Data suggestions the capacity of large scale patterns, correlations, and temporal trends, analysis
of outcomes.

 Big data provide high computational resources for real-time processing, captured in a timely manner.

 And accurate diagnosis has a great potential to interpret the strange mystery of the human brain.

 The development of Big Data analytics moves from report forecasting, description, decision
optimization predictive modeling.
 5 Contd..
 Machine learning focuses on the development of computer programs that can access data and use it
learn for themselves.

 Machine learning has played an essential role in big data systems due to its ability to efficiently
discover hidden information and valuable knowledge.

 Appreciations to the advanced technology of machine learning and medical imaging for the rapid
development of undergone computerized healthcare.

 Machine Learning is a data analysis of application belongs to build a model that desired predicted
output for available data by predictive and statistical features.
 6 AIM & OBJECTIVES
 Automated detection of Alzheimer’s Disease from the EEG data will reduce the time of diagnosis and
make possible to target the treatment for the Alzheimer’s Disease affected patients.
 The proposed method using EEG signal Alzheimer’s Disease are analyzed using advanced tools using
machine learning and deep learning algorithms.
 Prediction of Alzheimer’s with stages through the proposed Machine Learning algorithm will justify
specificity, sensitivity, and accuracy of this research.
 Advanced machine learning technique and statistical performance of the proposed algorithm
accurately detects the Alzheimer’s diseases of a person.
7 PROPOSED ARCHITECTURE
EEG Signal DWT

Pre-Processing Machine Learning

Feature Extracted

CSA (Clonal Selection

Brain Algorithm)

Disease Analyzing Using

EEG signal

Early Stages
Alzheimer’s Disease Alzheimer’s Disease

Stages Classification

Severe Stages
Affected Unaffected
 8 INTRODUCTION

 The Discrete Wavelet Transform(DWT) is used scaling function and implements the threshold of

feature extracted to determine the noisy data from the EEG signal. By applying DWT in connection

with Convolutional neural network (CNN) obtained novel and reliable classification with accuracy.

 The comparisons between the established classifiers were mainly based on the exploration of the

receiver operating characteristic (ROC) curves as well as a sum of scalar performance measures

concerning the classification.

 9 PROBLEM STATEMENT
 A clinical approach of EEG is primarily used for detecting one of the neurological disorders of Alzheimers

 Time-consuming affects the neurologist performance and maximum of the laborious process.

 The manual assessment puts a heavy burden on neurologists for analyzing EEG brain signals.

 Alzheimer’s Disease occur due to the functionality of neurological disorder in the brain which can affect
patient’s health.

 However the detection of current approaches is manually detected by domain experts but this mainly relies
on the limited features.

 which are inflexible while detecting a huge amount of EEG data and Alzheimer’s exaggerated patients.
10 PROPOSED SYSTEM
 Machine Learning (ML) techniques are used for predicting Alzheimer’s Disease from the given
dataset of Electroencephalograms (EEG) signals.

 However, there are two major concerns that are noisy removal form pre-processing of EEG signal and
feature extraction.

 To increase the computational speed of the preprocessing method for Alzheimer’s Disease
classification through a Discrete Wavelet Transform (DWT).

 The proposed method of Logistic Regression as well as CLONALG classifier was compared with the
classification relations of EEG signals to detect Alzheimer’s Disease.

 The Neural network of the CLONALG algorithm is used to compare the result of classification with
any of the outcomes of an Alzheimer’s Disease or Alzheimer’s Disease that were accurately analyzed.
 DATA FLOW DIAGRAM
11
EEG DATASET

Initialize the parameter

DATA PREPROCESSING

Preprocessing of Data Feature Selection Removing Noisy Data

EEG SIGNAL

DWT

Testing Data Training Data

CLONALG Selection Algorithm

Diagnostic Alzheimer's Diseases with

Level
12 Literature Survey
Title Methods/Techniques Demerits
Systematic Review on Resting-State Notwithstanding over the last decade dementia cases estimated worldwide.
EEG for Alzheimer’s Disease Electroencephalography(EEG) has
Diagnosis and Progression Assessment emerged as a noninvasive alternative
technique for the study of AD
 
Alzheimer’s Disease And Dementia Deep Learning represents the true There is currently no cure for most
Detection From 3D Brain MRI Data types of dementia, but treatments,
bleeding edge of Machine Intelligence.
Using Deep Convolutional Neural advice, and support are available.
Networks Convolutional Neural Networks are
biologically inspired Multilayer
perceptron
13 Literature Survey -- contd.,
Title Methods/Techniques Demerits

Recent Progress in Alzheimer’s These advances have This exercise inspired us to write a
tremendously increased our multipart review reviewing the most
Disease Research, Part 1: understanding of this disease and significant contributions in the field in the
Pathology reinforced just how complex AD. last five years.
 

The ability of several statistical Six classification problems are addressed,

EEG Window Length and spectral features to detect AD including the discrimination from whole-
Evaluation for the Detection of from electroencephalographic brain dynamics and separately from
Alzheimer’s Disease over (EEG) recordings is evaluated. specific brain regions
Different Brain Regions in order to highlight any alterations of the
cortical regions.
.
14 Literature Survey -- contd.,
Title Methods/Techniques Demerits

Diagnosis of Alzheimer’s Alzheimer’s disease is chronic Fast Fourier series, is not standard in the
Disease using Machine condition that leads to field of extraction by a sign from an EEG
Learning degeneration of brain cells leading signal
at memory
enervation
.
 
A Clonal Selection Algorithm Big-OPT problem is to rebuild the A parallel
for the Electro recorded signals implementation of CLONALG is under
Encephalography Signals in the goal of removing the investigation in order to
Reconstruction artifacts as maximum as possible reduce the running time and tackle larger
scale instances.
15 CONCLUSION

 This research concluded with new methods based on the EEG signals for detecting a disease of
Alzheimer’s Disease.

 CLONALG algorithm are used to classify automatic detection of seizure and also the affected stages
are calculated through Electroencephalography with accurate performance.

 Obtaining a promising result with the high rates of accurate classification of the individual human
EEG Signal that obtaining capable results.

 The experimental result shows the best-fit method with minimum time efficiently.
16 References
Raymundo Cassani “Systematic Review on Resting-State EEG for Alzheimer’s
Disease Diagnosis and Progression Assessment” , Hindawi Disease Markers
Volume 2018, Article ID 5174815”

H.M. Tarek Ullah,” Alzheimer’s Disease And Dementia Detection From 3D Brain
MRI Data Using Deep Convolutional Neural Networks”, 2018 3rd International
Conference for Convergence in Technology (I2CT) The Gateway Hotel, XION
Complex, Wakad Road, Pune, India. Apr 06-08, 2018

Francis Theodor Hane ” Recent Progress in Alzheimer’s Disease Research, Part 1:

Pathology ”, Journal of Alzheimer's disease: JAD 57(1):1-27, 2017.

KaterinaD. Tzimourta . “EEG Window Length Evaluation for the Detection of

Alzheimer’s Disease over Different Brain Regions”. Brain Sci. 2019, 9, 81.
17
References
• LOUKDACHE and EL MAJDOULI “A Clonal Selection Algorithm for
the Electro Encephalography Signals Reconstruction” , 3rd International
Conference on Electrical and Information Technologies ICEIT’2017”
• Ronghui Ju, Chenhui Hu and Quanzheng Li, “Early Diagnosis of
Alzheimer’s Disease Based on Resting-State Brain Networks and Deep
Learning” , 1545-5963 (c) 2017 IEEE.
• Leandro N. de Castro and Fernando J. Von Zuben , “Learning and
Optimization Using the ClonalSelection Principle” , IEEE
TRANSACTIONS ON EVOLUTIONARY COMPUTATION, VOL. 6,
NO. 3, JUNE 2018.
18

THANK YOU