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    LMM

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    aira khan
    This document discusses drug treatments for cognitive impairment and dementia. It notes that while the drug galantamine may improve behavioral symptoms in severe dementia, the efficacy of this class of drugs in severe cases is unclear. Memantine, which has a different mode of action, is well tolerated but evidence of its efficacy is limited to moderate to severe dementia. Both cholinesterase inhibitors and memantine are less effective for vascular dementia than other forms, and their efficacy for behavioral disturbances is not established though some small improvements were seen in manufacturer trials and analyses.

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    LMM

    Uploaded by

    aira khan
    4 views1 page
    This document discusses drug treatments for cognitive impairment and dementia. It notes that while the drug galantamine may improve behavioral symptoms in severe dementia, the efficacy of this class of drugs in severe cases is unclear. Memantine, which has a different mode of action, is well tolerated but evidence of its efficacy is limited to moderate to severe dementia. Both cholinesterase inhibitors and memantine are less effective for vascular dementia than other forms, and their efficacy for behavioral disturbances is not established though some small improvements were seen in manufacturer trials and analyses.

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    This document discusses drug treatments for cognitive impairment and dementia. It notes that while the drug galantamine may improve behavioral symptoms in severe dementia, the efficacy of this class of drugs in severe cases is unclear. Memantine, which has a different mode of action, is well tolerated but evidence of its efficacy is limited to moderate to severe dementia. Both cholinesterase inhibitors and memantine are less effective for vascular dementia than other forms, and their efficacy for behavioral disturbances is not established though some small improvements were seen in manufacturer trials and analyses.

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    Download as PPTX, PDF, TXT or read online from Scribd
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    4 views1 page

    LMM

    Uploaded by

    aira khan
    This document discusses drug treatments for cognitive impairment and dementia. It notes that while the drug galantamine may improve behavioral symptoms in severe dementia, the efficacy of this class of drugs in severe cases is unclear. Memantine, which has a different mode of action, is well tolerated but evidence of its efficacy is limited to moderate to severe dementia. Both cholinesterase inhibitors and memantine are less effective for vascular dementia than other forms, and their efficacy for behavioral disturbances is not established though some small improvements were seen in manufacturer trials and analyses.

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    LMM

    Moreover, the efficacy of this class of drugs in severe dementia is unclear, although behavioral symptom
    improvement was identified for galantamine (Institute for Quality and Efficiency in Healthcare, 2014). A fourth
    drug for the treatment of cognitive impairment, memantine, has a different mode of action and is well
    tolerated, but evidence for its efficacy is limited to people with moderate to severe dementia. Cholinesterase
    inhibitors (ChEIs) and memantine are less efficacious in vascular dementia than other forms. ChEIs and
    memantine’s efficacy in the treatment of behavioral disturbances is not established; manufacturer-sponsored
    licensing trials and post hoc analyses indicate small improvements.

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