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Marius Janušauskas

The Lithuanian University of Health


Sciences
Faculty of medicine
Medicine

Dopamine detox
M21/10
Table of contents
• Whats is dopamine?
• Things that drive human action
• Reward system
• Pathways
• Mechanism
• Overstimulation
• Simplified
• “Dopamine detox” is flawed
• How does dopamine detox work?
• History
• What is dopamine detox for
• Types of dopamine detox
• Pros and cons
What is dopamine?
• “Happy hormone” (spikes
then we feel something
pleasurable)
• Neurotransmitter,
chemical messenger
• Affects behavioral and
physical functions:
• Learning
• Motivation
• Sleep
• Mood
• Attention
• Primary driver of brain’s
reward system
• Key role in developing
addictive habits
Things that drive human actions

Necessities – Rewards
food, sleep,
avoidance of
pain
To elicit – sukelti
Circuitry – grandinė
Reward system: pathways
• Neurons that comprise the reward system communicate using dopamine
• The most important dopamine pathway - mesolympic
• Ventral tegmental area (VTA) (middle brain) -> nucleus accumbens
• Repetition of the rewarding behavior

Pathway - kelias
Reward system: mechanism
Reward system: overstimulation
• More dopamine ≠ more happiness
• Very stimulating activities interfere with neuron communication process
• Repeated exposure numbs the dopamine receptors
Reward system: simplified
Reward threshold
4

0
Addicted person In between Person on dopamine
detox

To influx - užplūsti
Mundane - kasdieniškas
“Dopamine detox” is flawed
• A true “dopamine detox” is impossible
• Low dopamine levels would have severe consequences
• Dopamine is not the problem

Degenerative - degeneracinis
How does dopamine detox work?
• 6 behaviors that dopamine detox targets:
• Emotional eating
• Excessive internet usage and gaming
• Gambling and shopping
• Porn
• Thrill and novelty seeking
• Recreational drugs
• Avoiding dopamine triggers
• Should be boring
• Desired result
History
• Dr. Cameron Sepah is the creator of dopamine detox
• Based on cognitive behavioral therapy (CBT)
• His goals
Who is dopamine detox for?
Types of dopamine detox
Pros and cons
• Increased ability to focus • It is very simplistic
• Developed greater self-discipline • Misleading
• Greater life satisfaction • May induce unrealistic expectations
• • Not scientifically proven
Improved emotion regulation
• Addicted people wouldn’t benefit much
Which part of the brain
dopamine is produced?
What’s the goal of dopamine
detox?
What are a few of compulsive
behaviors that dopamine detox
targets?
Sources
• Motivation: Why You Do the Things You Do (brainfacts.org)
• Addiction: Decreased reward sensitivity and increased expectation se
nsitivity conspire to overwhelm the brain's control circuit - PMC (nih.g
ov)
• Dopamine Fasting Probably Doesn't Work, Try This Instead (psychcent
ral.com)
• Science: You Now Have a Shorter Attention Span Than a Goldfish | Ti
me
• The Role of Dopamine as a Neurotransmitter in the Human Brain - Enz
o Life Sciences
• Neurotransmitter Clearance – Foundations of Neuroscience (msu.edu)
• Brain Reward System - Simply Psychology

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