Bioinformatics (BIO213)

Session 2

Slide content: Various textbooks, Internet sources

1
Deoxyribonucleic acid (DNA) and Ribonucleic acid (RNA)

• DNA Double helix structure,

• Base-pairing: Nitrogen bases, bonds, etc …
microbenotes.com
2
 Transcription

• DNA Directed RNA polymerases are of 4 types: RNA Pol I, II, III and IV
• What are control elements?
3
Transcription vs Replication

4
Splicing

5
Gehring and Roignant, 2020, Trends in Genetics
Translation

6
Translation

7
Translation

8
Codons and Amino acid

9
Levels of protein structure

10
Dihedral angles and Ramachandran plot
The relative probabilities of amino
acids in common secondary structures

G N Ramachandran 11
Visualization of aspects of protein structure

12
Mind map of key factors in central dogma of
biology

13
Thank You

14