TPN, Tetes Mata

TPN
KANDUNGAN TPN
• Dextrose
• Asam Amino
• Lipid
• Elektrolit
• vitamin
Pasien Anak BBLR neonates BB=2kg
• Lipid 20%: 1g/kgBB/hari.
• Aminosteril 6% 1g/kbBB/hari
• Dextrosa 12,5%= 190mL/hari
• Kalium = 2 meq/hari
• Ca gluconas= 1meq/hari
Contoh sediaan tetes mata
• Gentamycin 0,9% tetes mata (5mL)
• Cefazolin 3,3% tetes mata (15mL)
Compatibility
• Solubility
• Stability

Faktor yang mempengaruhi:

1. Suhu.
2. Wadah.
3. Waktu.
4. Pelarut.
• microgram (mcg)
• miligram (mg)
• Gram (g)
• Mililiter (mL)
• Liter (L)
• meq
1. NaCl 3%= 0,513 meq/mL
2. NaCl 0,9%= 0,154 meq/mL
3. NaCl 0,45 %= 0,077 meq/mLbb
4. Bicnat IV 8,4%= 1 meq/mL
5. Ca Gluc 10 % IV= 0,46 meq/mL
6. KCL IV= 1 meq/mL.
7. Bicnat capsul 500 mg= 6 meq------- kapsul no (0)
8. KcL kapsul 500 mg= 6,7 meq------------kapsul no (0)
9. NaCl kapsul 500 mg =8 meq------------kapsul no (1)
10. CaCo3 kapsul 500 mg= 10 meq-------------- kapsul no (0)
Dosis Pengenceran
• M1.V1=M2.Vtotal (V1+pengencer)
• M1.V1+ M2.V2=M3.V total

• M = Konsentrasi
• V =Volume
Kasus TPN
Inf D7,8%= D5 ¼ NS 115 mL + D40% 10 mL+ KcL 1 meq + Ca Gluc 2 meq
• M1v1+M2V2=M3.Vtot
• 5.115+40.10=M3.130(115+10+1+4)mL
• M3=7,5%
D9%= D5 ¼ NS 132 mL + D40% 4 mL +NaCL 3% 2mL + KCl 2 meq
• 5.132+40.4=M3.(132+4+2+2)
• M3=5,8%
Dextrose
Kasus 1:
Pasien neonatus BBLR BB= 2kg
• Advice TPN: D 12,5% 190 mL/24 jam, K= 2meq/24 jam, Lipid 10 mL/24
jam, ca = 2meq/24 jam
Kasus 2:
• Pasien PICU BB 15 kg
• Advice TPN : Dextrose 10% 12 tpm, Asam Amino 6% 50 mL/24 jam,
Lipid 20 mL/24 jam.