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DISTRESS
SYNDROME
(ARDS)
Alka.S.Kandula
ROLL No: 6
RESPIRATORY DISTRESS SYNDROME
(ARDS)
Acute respiratory distress syndrome (ARDS) is a life-threatening lung
condition that prevents enough oxygen from getting into the blood.
Acute respiratory distress syndrome was first described in 1967 by
Ashbaugh and colleagues.
ARDS is also referred with variety of terms like:
• Stiff Lung
• Shock Lung
• Wet Lung
• Post traumatic lung
• Adult respiratory distress syndrome
• Adult hyaline membrane disease
• Capillary leak syndrome
• Congestive atelectasis
DEFINITION
Acute respiratory distress syndrome (ARDS) is
a sudden and progressive form of acute
respiratory failure in which the alveolar
capillary membrane becomes damaged and
more permeable to intravascular fluid resulting
in severe dyspnea , hypoxemia and diffuse
pulmonary infilrates.
ETIOLOGY AND RISK FACTORS
Direct Lung Injury
-Common causes
• Aspiration of gastric contents or other substances.
• Viral/bacterial pneumonia
-Less Common causes
• Chest trauma
• Embolism : fat , air , amniotic fluid
• Inhalation of toxic substances
• Near-drowning
• O2 toxicity
• Radiation pneumonitis
ETIOLOGY AND RISK FACTORS
Indirect Lung Injury
-Common causes
• Sepsis
• Sereve traumatic injury
-Less Common causes
• Acute pancreatitis
-Less Common causes
• Anaphylaxis
• Prolonged Cardiopulmonary bypass surgery
• Disseminated intravascular coaglation
• Multiple blood transfusion
• Narcotic drug overdose (example - heroine)
• Nonpulmonary systemic disease
• Severe head injury
• Shock
• Massive blood transfusion
STAGES OF ODEMA FORMATION IN
ARDS
SCHEMATIC REPRESENTATION OF
PATHOPHYSIOLOGY OF ARDS
CLINICAL MANIFESTATION
Early signs/symptoms
• Restlessness
• Dyspnea
• Lowbloodpressure
• Confusion
• Extreme tierdness
• Change in patient’s behvior
Mood swing
Disorientation
Change in LOC
• If tneumonia is causing ARDS then client may have
Cough
Fever
CLINICAL MANIFESTATION
Late signs/symptoms
• Severe difficulty in breathing i.e, laboured rapid , breathing.
• Shortness of breath.
• Tachycardia
• Cyanosis (blue skin, lips and nails)
• Think frothy sputum
• Metabolic acidosis
• Abnormal breath sounds, like crackles
PaCo2 with respiratory alkalosis
PaCo2
DIAGNOSTIC EVALUTION
On physical examination
Auscultation reveals abnormal breath sounds
The first tests done are :
Arterial blood gas analysis
Blood tests
Chest x-rays
Bronchoscopy
Sputum cultures and analysis
• Other tests are :
Chest CT scan
Echocardiogram
COMPLICATIONS
Common complications are:
Nosocomial pneumonia:
Barotrauma
Renal failure
other complications are:
O2 toxicity
Stress ulcers
Tracheal ulceration
Blood clots leading to deep vein thrombosis
Pulmonary embolism
MEDICAL MANAGEMENT
Persons with ARDS are hospitalized and require
treatment in an intensive care unit.
No specific therapy for ARDS exists.
Supportive measures:
Supplemental oxygen
Mechanical respirator
Positioning strategies
Turn the patient from supine to prone.
Another position is lateral rotation therapy
MEDICAL MANAGEMENT
MEDICATIONS:
Antibiotics
Anti-inflammatory drugs; such as corticosteroids
Diuretics
Drug to raise blood pressure
Anti-anxiety
Muscle relaxers
Inhaled drugs (Bronchodilators)
PATIENT LYING PRONE ON
VALLMAN PRONE POSITIONER
THANK YOU