Scientists at Yale University managed to preserve the function of multiple organs in pigs, such as the brain, heart, liver and kidneys, one hour after the animals had died. This research could help prolong the viability of vital human organs destined for transplants, thousands of which are discarded each year because they are not immediately preserved. The researchers induced cardiac arrest in pigs and left the carcasses at room temperature for an hour before infusing their blood with a solution called OrganEx, which contains various compounds. Using a machine, they circulated the mixture for six hours and observed signs of resuscitation in the dying organs. Further study is still needed to determine how well the organs can function.
Scientists at Yale University managed to preserve the function of multiple organs in pigs, such as the brain, heart, liver and kidneys, one hour after the animals had died. This research could help prolong the viability of vital human organs destined for transplants, thousands of which are discarded each year because they are not immediately preserved. The researchers induced cardiac arrest in pigs and left the carcasses at room temperature for an hour before infusing their blood with a solution called OrganEx, which contains various compounds. Using a machine, they circulated the mixture for six hours and observed signs of resuscitation in the dying organs. Further study is still needed to determine how well the organs can function.
Scientists at Yale University managed to preserve the function of multiple organs in pigs, such as the brain, heart, liver and kidneys, one hour after the animals had died. This research could help prolong the viability of vital human organs destined for transplants, thousands of which are discarded each year because they are not immediately preserved. The researchers induced cardiac arrest in pigs and left the carcasses at room temperature for an hour before infusing their blood with a solution called OrganEx, which contains various compounds. Using a machine, they circulated the mixture for six hours and observed signs of resuscitation in the dying organs. Further study is still needed to determine how well the organs can function.
In a world medical first, scientists at Yale University (United States) managed
to preserve the function of multiple organs in pigs, such as the brain, heart, liver and kidneys, one hour after the animals had died. This research could help prolong the viability of vital human organs destined for transplants, thousands of which are discarded each year because they are not immediately preserved. Organs usually need to be removed right after the heart stops pumping blood to make them viable. But a sapphire-blue solution called OrganEx, developed by neuroscientist Nenad Sestan and his team, allowed them to restore basic organ functions long after the tissues had last received fresh blood. The researchers induced cardiac arrest in pigs and left the carcasses at room temperature for an hour before infusing their blood with OrganEx, which contains amino acids, vitamins, metabolites, and 13 other compounds. Using a machine, they circulated the mixture for six hours and observed signs of resuscitation in the dying organs: heart cells began to beat, liver cells absorbed glucose from the blood, and DNA repair resumed. Still, Sestan urges caution. "We can say that the heart beats, but to what extent does it beat like a healthy heart: that will require further study." Next steps will include transplanting OrganEx-treated organs into live pigs to see how they work. BIBLIOGRAPHIC SOURCE Staff, N. G. (2022). Los 22 descubrimientos científicos más impactantes de 2022. Nacional Geographi.